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anti-Rat (Rattus) MERTK antibody for Immunofluorescence (Paraffin-embedded Sections)

Recommended MERTK Antibody (supplied by: Log in to see )

Antigen
C-Mer Proto-Oncogene Tyrosine Kinase (MERTK) Antibodies
  • C-EYK
  • c-mer
  • DKFZp469D2215
  • Eyk
  • Mer
  • MER
  • MERTK
  • nmf12
  • Nyk
  • rdy
  • RP38
  • si:ch1073-268l12.2
Epitope
AA 530-580
36
35
12
5
4
3
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
159
45
32
5
1
1
Host
Rabbit
109
27
26
5
Clonality
Polyclonal
Conjugate
This MERTK antibody is un-conjugated
11
8
7
7
6
6
2
2
2
1
1
1
1
1
1
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
109
96
54
15
14
13
11
10
10
8
3
2
Supplier
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Catalog No. ABIN669966
$ 269.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008846439 ABIN885865 IF (p) Alexa Fluor 488 Rabbit IgG AA 530-580 Log in to see Polyclonal
0.0008846439 ABIN885866 IF (p) Alexa Fluor 350 Rabbit IgG AA 530-580 Log in to see Polyclonal
0.0008846439 ABIN885863 IF (p) Alexa Fluor 647 Rabbit IgG AA 530-580 Log in to see Polyclonal
0.0008846439 ABIN885862 IF (p) Alexa Fluor 555 Rabbit IgG AA 530-580 Log in to see Polyclonal
0.0008846439 ABIN669969 IF (p) Cy3 Rabbit IgG AA 530-580 Log in to see Polyclonal
0.0008846439 ABIN669970 IF (p) Cy5 Rabbit IgG AA 530-580 Log in to see Polyclonal
0.0008846439 ABIN669972 IF (p) Cy7 Rabbit IgG AA 530-580 Log in to see Polyclonal
0.0008846439 ABIN669973 IF (p) FITC Rabbit IgG AA 530-580 Log in to see Polyclonal
0.0008846439 ABIN669971 IF (p) Cy5.5 Rabbit IgG AA 530-580 Log in to see Polyclonal
0.0008846439 ABIN2804148 IF (p) Alexa Fluor 594 Rabbit IgG AA 530-580 Log in to see Polyclonal

Similar anti-MERTK Antibodies

Application / Reactivity Rat (Rattus) Mouse (Murine)
Confocal Microscopy (CM) 8 Antibodies 8 Antibodies
ELISA 13 Antibodies 15 Antibodies
Flow Cytometry (FACS) 2 Antibodies 2 Antibodies
Immunocytochemistry (ICC) 9 Antibodies 9 Antibodies
Immunofluorescence (IF) 9 Antibodies 9 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies 11 Antibodies
Immunohistochemistry (IHC) 12 Antibodies 17 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 2 Antibodies 2 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 3 Antibodies
Immunoprecipitation (IP) 9 Antibodies
Western Blotting (WB) 20 Antibodies
Enzyme Immunoassay (EIA) 1 Antibodies

General

Antigen C-Mer Proto-Oncogene Tyrosine Kinase (MERTK) Antibodies
Epitope AA 530-580
(36), (35), (12), (5), (4), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(159), (45), (32), (5), (1), (1)
Host Rabbit
(109), (27), (26), (5)
Clonality
Polyclonal
Conjugate This MERTK antibody is un-conjugated
(11), (8), (7), (7), (6), (6), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(109), (96), (54), (15), (14), (13), (11), (10), (10), (8), (3), (2)
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Product Details anti-MERTK Antibody

Target Details MERTK Application Details Handling Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from human of human MERTK
Isotype IgG

Target Details MERTK

Product Details anti-MERTK Antibody Application Details Handling Images back to top
Antigen
Alternative Name MERTK (MERTK Antibody Abstract)
Background

Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to several ligands including LGALS3, TUB, TULP1 or GAS6. Regulates many physiological processes including cell survival, migration, differentiation, and phagocytosis of apoptotic cells (efferocytosis). Ligand binding at the cell surface induces autophosphorylation of MERTK on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with GRB2 or PLCG2 and induces phosphorylation of MAPK1, MAPK2, FAK/PTK2 or RAC1. MERTK signaling plays a role in various processes such as macrophage clearance of apoptotic cells, platelet aggregation, cytoskeleton reorganization and engulfment. Functions in the retinal pigment epithelium (RPE) as a regulator of rod outer segments fragments phagocytosis. Plays also an important role in inhibition of Toll-like receptors (TLRs)-mediated innate immune response by activating STAT1, which selectively induces production of suppressors of cytokine signaling SOCS1 and SOCS3.

Subcellular location: Cytoplasm


Synonyms: MER, RP38, c-Eyk, c-mer, Tyro12, Tyrosine-protein kinase Mer, Proto-oncogene c-Mer, Receptor tyrosine kinase MerTK, MERTK
Gene ID 10461
UniProt Q12866
Research Area Neurology, Tyrosine Kinases
Pathways RTK Signaling

Application Details

Product Details anti-MERTK Antibody Target Details MERTK Handling Images back to top
Application Notes WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
Restrictions For Research Use only

Handling

Product Details anti-MERTK Antibody Target Details MERTK Application Details Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

Images

Product Details anti-MERTK Antibody Target Details MERTK Application Details Handling back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-MERTK antibody (C-Mer Proto-Oncogene Tyrosine Kinase) (AA 530-580) (ABIN669966) Formalin-fixed and paraffin embedded mouse spleen labeled with Rabbit Anti C-Mer/MERT...