anti-Human MUSK antibody for Enzyme Immunoassay

Recommended MUSK Antibody (supplied by: Log in to see )

Antigen
Muscle, Skeletal, Receptor Tyrosine Kinase (MUSK) Antibodies
  • unp
  • fj98e12
  • zgc:63467
  • wu:fj98e12
  • si:dz46m7.2
  • si:dz57f23.3
  • si:busm1-57f23.3
  • musk-A
  • MuSK
  • MUSK
  • Mdk4
  • Mlk
  • Nsk1
  • Nsk2
  • Nsk3
  • muscle
  • muscle, skeletal, receptor tyrosine kinase
  • MUSK
  • musk
  • musk-A
  • Musk
Epitope
C-Term
25
18
14
11
7
6
6
6
6
4
3
2
1
1
1
1
1
Reactivity
Human
118
52
41
2
2
2
1
1
1
1
Host
Rabbit
98
29
3
Clonality
Polyclonal
Conjugate
This MUSK antibody is un-conjugated
6
6
5
4
4
4
1
1
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
96
71
61
28
22
13
13
5
5
3
3
1
1
1
Supplier
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Catalog No. ABIN359903
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN359904 EIA WB Rabbit Ig Log in to see Polyclonal 1
1 ABIN5552247 EIA IHC (p) WB Rabbit Ig Fraction N-Term Log in to see Polyclonal
1 ABIN1108329 EIA IF IHC (p) Mouse IgG1 Log in to see 10A4

General

Antigen Muscle, Skeletal, Receptor Tyrosine Kinase (MUSK) Antibodies
Epitope C-Term
(25), (18), (14), (11), (7), (6), (6), (6), (6), (4), (3), (2), (1), (1), (1), (1), (1)
Reactivity Human
(118), (52), (41), (2), (2), (2), (1), (1), (1), (1)
Host Rabbit
(98), (29), (3)
Clonality
Polyclonal
Conjugate This MUSK antibody is un-conjugated
(6), (6), (5), (4), (4), (4), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(96), (71), (61), (28), (22), (13), (13), (5), (5), (3), (3), (1), (1), (1)
Pubmed 1 reference available
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Product Details anti-MUSK Antibody

Target Details MUSK Application Details Handling ProductDetails: References for anti-MUSK antibody (ABIN359903) Images
Specificity This antibody reacts to MUSK.
Purification Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human MUSK.
Isotype Ig

Target Details MUSK

Product Details anti-MUSK Antibody Application Details Handling ProductDetails: References for anti-MUSK antibody (ABIN359903) Images back to top
Antigen
Alternative Name MUSK (MUSK Antibody Abstract)
Background Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.The tyrosine kinase (TK) group is mainly involved in the regulation of cell-cell interactions such as differentiation, adhesion, motility and death. There are currently about 90 TK genes sequenced, 58 are of receptor protein TK (e.g. EGFR, EPH, FGFR, PDGFR, TRK, and VEGFR families), and 32 of cytosolic TK (e.g. ABL, FAK, JAK, and SRC families).Synonyms: Muscle, Muscle-specific kinase receptor, skeletal receptor tyrosine-protein kinase
Gene ID 4593, 9606
UniProt O15146
Research Area Extracellular Matrix, Tyrosine Kinases, Kinases/Phosphatases
Pathways RTK Signaling, Regulation of Muscle Cell Differentiation, Synaptic Membrane, Regulation of Cell Size, Skeletal Muscle Fiber Development

Application Details

Product Details anti-MUSK Antibody Target Details MUSK Handling ProductDetails: References for anti-MUSK antibody (ABIN359903) Images back to top
Application Notes ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-MUSK Antibody Target Details MUSK Application Details ProductDetails: References for anti-MUSK antibody (ABIN359903) Images back to top
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

ProductDetails: References for anti-MUSK antibody (ABIN359903)

Product Details anti-MUSK Antibody Target Details MUSK Application Details Handling Images back to top
Background publications

Cantrell: "Phosphoinositide 3-kinase signalling pathways." in: Journal of cell science, Vol. 114, Issue Pt 8, pp. 1439-45, 2001

Images

Product Details anti-MUSK Antibody Target Details MUSK Application Details Handling ProductDetails: References for anti-MUSK antibody (ABIN359903) back to top
Supplier Images
 image for anti-Muscle, Skeletal, Receptor Tyrosine Kinase (MUSK) (C-Term) antibody (ABIN359903) anti-Muscle, Skeletal, Receptor Tyrosine Kinase (MUSK) (C-Term) antibody
 image for anti-Muscle, Skeletal, Receptor Tyrosine Kinase (MUSK) (C-Term) antibody (ABIN359903) anti-Muscle, Skeletal, Receptor Tyrosine Kinase (MUSK) (C-Term) antibody (Image 2)