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anti-Rat (Rattus) Phospholipase C gamma 2 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended Phospholipase C gamma 2 Antibody (supplied by: Log in to see )

Antigen
Phospholipase C gamma 2 (PLCG2) Antibodies
  • APLAID
  • FCAS3
  • Plcg-2
  • PLCgamma2
Epitope
pTyr1217
40
32
21
21
13
5
5
4
4
3
2
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
258
120
116
6
Host
Rabbit
193
65
Clonality
Polyclonal
Conjugate
This Phospholipase C gamma 2 antibody is un-conjugated
7
7
6
6
6
4
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
181
85
80
57
38
34
33
14
12
3
2
1
1
Supplier
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Catalog No. ABIN319283
$ 357.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008982679 ABIN319401 IF IHC (p) Rabbit Tyr1217 Log in to see Polyclonal 4
0.0008982679 ABIN272070 IHC (p) WB Rabbit Log in to see Polyclonal
0.0008982679 ABIN271905 EIA IHC (p) WB Rabbit Log in to see Polyclonal
0.0008982679 ABIN700375 IF (p) IHC (p) WB Rabbit IgG AA 660-710 Log in to see Polyclonal 1
0.0008982679 ABIN373801 IHC (p) Rabbit AA 1213-1232 Log in to see Polyclonal
0.0008982679 ABIN744848 IF (p) IHC (p) WB Rabbit IgG pTyr759 Log in to see Polyclonal 1
0.0008982679 ABIN127211 IHC (p) IP WB Rabbit C-Term Log in to see Polyclonal
0.0008982679 ABIN700377 IHC (p) WB Biotin Rabbit IgG AA 660-710 Log in to see Polyclonal
0.0008982679 ABIN700384 IHC (p) WB HRP Rabbit IgG AA 660-710 Log in to see Polyclonal
0.0008982679 ABIN1738145 IHC (p) ELISA WB Rabbit IgG Internal Region Log in to see Polyclonal
0.0008982679 ABIN744857 IHC (p) WB HRP Rabbit IgG pTyr759 Log in to see Polyclonal
0.0008982679 ABIN744835 IHC (p) WB Biotin Rabbit IgG pTyr1217 Log in to see Polyclonal
0.0008982679 ABIN744842 IHC (p) WB HRP Rabbit IgG pTyr1217 Log in to see Polyclonal
0.0008982679 ABIN744850 IHC (p) WB Biotin Rabbit IgG pTyr759 Log in to see Polyclonal
0.0008982679 ABIN407912 IHC (p) IHC WB Rabbit IgG Log in to see Polyclonal
0.0008982679 ABIN744833 IF (p) IHC (p) WB Rabbit IgG pTyr1217 Log in to see Polyclonal
0.0008982679 ABIN711176 IF (p) IHC (p) WB Rabbit IgG pTyr753 Log in to see Polyclonal
0.0008982679 ABIN408076 IHC (p) IHC WB Rabbit IgG Log in to see Polyclonal

Top referenced anti-Phospholipase C gamma 2 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Similar anti-Phospholipase C gamma 2 Antibodies

Application / Reactivity Human Mouse (Murine) Rat (Rattus)
Western Blotting (WB) 182 Antibodies 66 Antibodies 64 Antibodies
Proximity Ligation Assay (PLA) 2 Antibodies
Intracellular Staining (ICS) 3 Antibodies 3 Antibodies 3 Antibodies
Immunoprecipitation (IP) 15 Antibodies 5 Antibodies 5 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 35 Antibodies 19 Antibodies 19 Antibodies
Immunohistochemistry (IHC) 81 Antibodies 46 Antibodies 44 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 1 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 34 Antibodies 34 Antibodies 34 Antibodies

General

Antigen Phospholipase C gamma 2 (PLCG2) Antibodies
Epitope pTyr1217
(40), (32), (21), (21), (13), (5), (5), (4), (4), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(258), (120), (116), (6)
Host Rabbit
(193), (65)
Clonality
Polyclonal
Conjugate This Phospholipase C gamma 2 antibody is un-conjugated
(7), (7), (6), (6), (6), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3)
Application Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(181), (85), (80), (57), (38), (34), (33), (14), (12), (3), (2), (1), (1)
Pubmed 3 references available
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Product Details anti-Phospholipase C gamma 2 Antibody

Target Details Phospholipase C gamma 2 Application Details Handling References for anti-Phospholipase C gamma 2 Antibody (ABIN319283) Images
Specificity This antibody detects endogenous levels of PLC-gamma 2 only when phosphorylated at Tyrosine 1217.
Purification Immunoaffinity Chromatography: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from Human PLC-gamma 2 around the phosphorylation site of Tyrosine 1217 (F-L-Yp-D-T).

Target Details Phospholipase C gamma 2

Product Details anti-Phospholipase C gamma 2 Antibody Application Details Handling References for anti-Phospholipase C gamma 2 Antibody (ABIN319283) Images back to top
Antigen
Alternative Name PLCG2 (PLCG2 Antibody Abstract)
Background Enzymes of the phospholipase C family catalyze the hydrolysis of phospholipids to yield diacylglycerols and water soluble phosphorylated derivatives of the lipid head groups. A number of these enzymes have specificity for phosphoinositides. Of the phosphoinositide specific phospholipase C enzymes, C beta is regulated by heterotrimeric G protein coupled receptors, while the closely related C gamma 1 and C gamma 2 enzymes are controlled by receptor tyrosine kinases. The C gamma 1 and C gamma 2 enzymes are composed of phospholipase domains that flank regions of homology to noncatalytic domains of the SRC oncogene product, SH2 and SH3.Synonyms: 1-phosphatidylinositol-4, 5-bisphosphate phosphodiesterase gamma-2, PLC-IV, PLC-gamma-2, Phosphoinositide phospholipase C-gamma-2, Phospholipase C-IV, Phospholipase C-gamma-2
Gene ID 5336
NCBI Accession NP_002652
UniProt P16885
Pathways RTK Signaling, WNT Signaling, Fc-epsilon Receptor Signaling Pathway

Application Details

Product Details anti-Phospholipase C gamma 2 Antibody Target Details Phospholipase C gamma 2 Handling References for anti-Phospholipase C gamma 2 Antibody (ABIN319283) Images back to top
Application Notes Immunohistochemistry (1/50-1/100).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-Phospholipase C gamma 2 Antibody Target Details Phospholipase C gamma 2 Application Details References for anti-Phospholipase C gamma 2 Antibody (ABIN319283) Images back to top
Concentration 1.0 mg/mL
Buffer PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide and 50 % Glycerol.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Store the antibody (in aliquots) at-20 °C.

References for anti-Phospholipase C gamma 2 Antibody (ABIN319283)

Product Details anti-Phospholipase C gamma 2 Antibody Target Details Phospholipase C gamma 2 Application Details Handling Images back to top
Background publications

Yue, Ku, Liu, Simon, Sanborn: "Molecular mechanism of the inhibition of phospholipase C beta 3 by protein kinase C." in: The Journal of biological chemistry, Vol. 275, Issue 39, pp. 30220-5, 2000

Yue, Dodge, Weber, Sanborn: "Phosphorylation of serine 1105 by protein kinase A inhibits phospholipase Cbeta3 stimulation by Galphaq." in: The Journal of biological chemistry, Vol. 273, Issue 29, pp. 18023-7, 1998

Mattaj: "A binding consensus: RNA-protein interactions in splicing, snRNPs, and sex." in: Cell, Vol. 57, Issue 1, pp. 1-3, 1989

Images

Product Details anti-Phospholipase C gamma 2 Antibody Target Details Phospholipase C gamma 2 Application Details Handling References for anti-Phospholipase C gamma 2 Antibody (ABIN319283) back to top
Supplier Images
 image for anti-Phospholipase C gamma 2 antibody (PLCG2) (pTyr1217) (ABIN319283) anti-Phospholipase C gamma 2 (PLCG2) (pTyr1217) antibody