anti-Human RYK antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended RYK Antibody (supplied by: Log in to see )

Antigen
RYK Receptor-Like Tyrosine Kinase (RYK) Antibodies
  • RYK
  • jtk5
  • ryk1
  • jtk5a
  • d3s3195
  • wu:fb37b12
  • wu:fi05b06
  • zgc:158381
  • MGC114645
  • D3S3195
  • JTK5
  • JTK5A
  • RYK1
  • AW536699
  • ERK-3
  • Vik
  • RYK receptor-like tyrosine kinase
  • ryk receptor-like tyrosine kinase
  • receptor-like tyrosine kinase
  • RYK
  • ryk
  • Ryk
Epitope
C-Term
14
14
11
11
10
9
8
8
4
4
3
3
3
2
2
1
1
1
1
1
1
1
1
1
Reactivity
Human
99
38
21
3
2
2
1
1
1
1
Host
Rabbit
67
23
11
5
Clonality
Polyclonal
Conjugate
This RYK antibody is un-conjugated
9
9
8
8
8
8
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
97
69
32
8
4
3
2
2
2
1
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Catalog No. ABIN359938
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN359937 EIA IHC (p) WB Rabbit Ig AA 150-200 Log in to see Polyclonal 5
1 ABIN392051 IHC (p) WB Rabbit Ig AA 561-591, C-Term Log in to see Polyclonal 1
1 ABIN392050 IHC (p) WB Rabbit Ig AA 160-190 Log in to see Polyclonal 2
1 ABIN5534651 IHC (p) WB Rabbit Ig Fraction AA 160-190 Log in to see Polyclonal
1 ABIN5534652 IHC (p) WB Rabbit Ig Fraction AA 561-591, C-Term Log in to see Polyclonal
1 ABIN4351516 ICC IF IHC IHC (p) Rabbit Log in to see Polyclonal
1 ABIN1841194 IHC (p) WB Rabbit AA 561-591 Log in to see Polyclonal
1 ABIN1841193 IHC (p) WB Rabbit AA 160-190 Log in to see Polyclonal

General

Antigen RYK Receptor-Like Tyrosine Kinase (RYK) Antibodies
Epitope C-Term
(14), (14), (11), (11), (10), (9), (8), (8), (4), (4), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(99), (38), (21), (3), (2), (2), (1), (1), (1), (1)
Host Rabbit
(67), (23), (11), (5)
Clonality
Polyclonal
Conjugate This RYK antibody is un-conjugated
(9), (9), (8), (8), (8), (8)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(97), (69), (32), (8), (4), (3), (2), (2), (2), (1)
Pubmed 1 reference available
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Product Details anti-RYK Antibody

Target Details RYK Application Details Handling ProductDetails: References for anti-RYK antibody (ABIN359938) Images
Specificity This antibody reacts to RYK.
Purification Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human RYK.
Isotype Ig

Target Details RYK

Product Details anti-RYK Antibody Application Details Handling ProductDetails: References for anti-RYK antibody (ABIN359938) Images back to top
Antigen
Alternative Name Tyrosine-Protein Kinase RYK (RYK Antibody Abstract)
Background RYK is an atypical member of the family of growth factor receptor protein tyrosine kinases, differing from other members at a number of conserved residues in the activation and nucleotide binding domains. This gene product belongs to a subfamily whose members do not appear to be regulated by phosphorylation in the activation segment. It has been suggested that mediation of biological activity by recruitment of a signaling-competent auxiliary protein may occur through an as yet uncharacterized mechanism. A nine nucleotide insertion in some transcripts results in the SLG variant. It is not established whether this is a product of alternative splicing or a second gene, since evidence for a second gene or pseudogene on chromosome 17 exists.Synonyms: JTK5A
Gene ID 6259, 9606
UniProt P34925
Research Area Kinases/Phosphatases
Pathways RTK Signaling, WNT Signaling, Regulation of Cell Size

Application Details

Product Details anti-RYK Antibody Target Details RYK Handling ProductDetails: References for anti-RYK antibody (ABIN359938) Images back to top
Application Notes ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-RYK Antibody Target Details RYK Application Details ProductDetails: References for anti-RYK antibody (ABIN359938) Images back to top
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

ProductDetails: References for anti-RYK antibody (ABIN359938)

Product Details anti-RYK Antibody Target Details RYK Application Details Handling Images back to top
Background publications

Keeble, Halford, Seaman, Kee, Macheda, Anderson, Stacker, Cooper: "The Wnt receptor Ryk is required for Wnt5a-mediated axon guidance on the contralateral side of the corpus callosum." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 26, Issue 21, pp. 5840-8, 2006

Images

Product Details anti-RYK Antibody Target Details RYK Application Details Handling ProductDetails: References for anti-RYK antibody (ABIN359938) back to top
Supplier Images
 image for anti-RYK Receptor-Like Tyrosine Kinase (RYK) (C-Term) antibody (ABIN359938) anti-RYK Receptor-Like Tyrosine Kinase (RYK) (C-Term) antibody
 image for anti-RYK Receptor-Like Tyrosine Kinase (RYK) (C-Term) antibody (ABIN359938) anti-RYK Receptor-Like Tyrosine Kinase (RYK) (C-Term) antibody (Image 2)