anti-Mouse (Murine) SHC1 antibody for Immunocytochemistry

Recommended SHC1 Antibody (supplied by: Log in to see )

Antigen
SHC (Src Homology 2 Domain Containing) Transforming Protein 1 (SHC1) Antibodies
  • SHC1
  • SHC
  • SHCA
  • P66shc
  • si:dkey-246i14.4
  • wu:fc10h03
  • shc
  • p66shc
  • Shc
  • ShcA
  • p66
  • SHC (Src homology 2 domain containing) transforming protein 1
  • Shc1p
  • squalene--hopene cyclase
  • src homology 2 domain-containing transforming protein C1
  • SHC1
  • shc1
  • LOC100229782
  • Shc1
Epitope
AA 385-495
41
39
19
17
15
15
14
10
10
9
7
7
5
4
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine)
226
180
140
10
6
5
2
2
1
1
1
1
1
Host
Mouse
209
29
Clonality
Monoclonal
Conjugate
This SHC1 antibody is un-conjugated
7
7
6
5
5
5
5
5
5
5
5
5
5
5
1
1
1
Application
ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC), Western Blotting (WB)
165
81
66
59
44
36
14
7
6
4
4
3
1
1
Options
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Catalog No. ABIN5542463
$ 451.61
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN2854911 ICC IF IHC (p) WB Rabbit IgG N-Term Log in to see Polyclonal
1 ABIN4353343 ICC IF IHC IHC (p) WB Rabbit IgG N-Term Log in to see Polyclonal
1 ABIN4881246 ELISA FACS ICC WB Mouse IgG1 AA 385-495 Log in to see 2F7C7
1 ABIN3032555 ICC IHC (fro) IHC (p) WB Rabbit IgG C-Term Log in to see Polyclonal

Similar anti-SHC1 Antibodies

Application / Reactivity Mouse (Murine) Human
ELISA 31 Antibodies 38 Antibodies
Enzyme Immunoassay (EIA) 3 Antibodies 4 Antibodies
Flow Cytometry (FACS) 2 Antibodies 5 Antibodies
Immunocytochemistry (ICC) 5 Antibodies 8 Antibodies
Immunofluorescence (IF) 31 Antibodies
Immunofluorescence (fixed cells) (IF/ICC) 2 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 66 Antibodies
Immunohistochemistry (IHC) 48 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 5 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 26 Antibodies
Immunoprecipitation (IP) 11 Antibodies
Western Blotting (WB) 111 Antibodies
Immunochromatography (IC) 1 Antibodies

General

Antigen SHC (Src Homology 2 Domain Containing) Transforming Protein 1 (SHC1) Antibodies
Epitope AA 385-495
(41), (39), (19), (17), (15), (15), (14), (10), (10), (9), (7), (7), (5), (4), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine)
(226), (180), (140), (10), (6), (5), (2), (2), (1), (1), (1), (1), (1)
Host Mouse
(209), (29)
Clonality (Clone)
Monoclonal   ( )
Conjugate This SHC1 antibody is un-conjugated
(7), (7), (6), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (1), (1), (1)
Application ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC), Western Blotting (WB)
(165), (81), (66), (59), (44), (36), (14), (7), (6), (4), (4), (3), (1), (1)
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Product Details anti-SHC1 Antibody

Target Details SHC1 Application Details Handling Images
Immunogen Purified recombinant fragment of human SHC1 (AA 385-495) expressed in E. Coli.
Clone 2F7C7
Isotype IgG1

Target Details SHC1

Product Details anti-SHC1 Antibody Application Details Handling Images back to top
Antigen
Alternative Name SHC1 (SHC1 Antibody Abstract)
Background This gene encodes three main isoforms that differ in activities and subcellular location. While all three are adapter proteins in signal transduction pathways, the longest (p66Shc) may be involved in regulating life span and the effects of reactive oxygen species. The other two isoforms, p52Shc and p46Shc, link activated receptor tyrosine kinases to the Ras pathway by recruitment of the GRB2/SOS complex. p66Shc is not involved in Ras activation. Unlike the other two isoforms, p46Shc is targeted to the mitochondrial matrix. Several transcript variants encoding different isoforms have been found for this gene.
Molecular Weight 62.8kDa
HGNC 6464
Pathways RTK Signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, ER-Nucleus Signaling, Signaling Events mediated by VEGFR1 and VEGFR2

Application Details

Product Details anti-SHC1 Antibody Target Details SHC1 Handling Images back to top
Application Notes ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400
Restrictions For Research Use only

Handling

Product Details anti-SHC1 Antibody Target Details SHC1 Application Details Images back to top
Format Liquid
Buffer PBS with 0.05 % sodium azide.
Storage 4 °C,-20 °C
Storage Comment 4°C, -20°C for long term storage

Images

Product Details anti-SHC1 Antibody Target Details SHC1 Application Details Handling back to top
Supplier Images
ELISA image for anti-SHC1 antibody (SHC (Src Homology 2 Domain Containing) Transforming Protein 1) (AA 385-495) (ABIN5542463) Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen ...
Western Blotting (WB) image for anti-SHC1 antibody (SHC (Src Homology 2 Domain Containing) Transforming Protein 1) (AA 385-495) (ABIN5542463) Western blot analysis using SHC1 mAb against human SHC1 (AA: 385-495) recombinant pro...
Western Blotting (WB) image for anti-SHC1 antibody (SHC (Src Homology 2 Domain Containing) Transforming Protein 1) (AA 385-495) (ABIN5542463) Western blot analysis using SHC1 mAb against HEK293 (1) and SHC1 (AA: 385-495)-hIgGFc...
Western Blotting (WB) image for anti-SHC1 antibody (SHC (Src Homology 2 Domain Containing) Transforming Protein 1) (AA 385-495) (ABIN5542463) Western blot analysis using SHC1 mouse mAb against NIH/3T3 cell lysate.
Flow Cytometry (FACS) image for anti-SHC1 antibody (SHC (Src Homology 2 Domain Containing) Transforming Protein 1) (AA 385-495) (ABIN5542463) Flow cytometric analysis of NIH/3T3 cells using SHC1 mouse mAb (green) and negative c...
Immunocytochemistry (ICC) image for anti-SHC1 antibody (SHC (Src Homology 2 Domain Containing) Transforming Protein 1) (AA 385-495) (ABIN5542463) Immunofluorescence analysis of A431 cells using SHC1 mouse mAb (green). Blue: DRAQ5 f...