You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-Human TIE1 antibody for Immunohistochemistry

Recommended TIE1 Antibody (supplied by: Log in to see )

Antigen
tyrosine Kinase with Immunoglobulin-Like and EGF-Like Domains 1 (TIE1) Antibodies
  • D430008P04Rik
  • JTK14
  • TIE
  • tie-1
Epitope
Extracellular Domain
20
17
14
13
12
11
6
5
4
4
4
3
3
3
2
2
1
Reactivity
Human
133
41
28
2
Host
Mouse
98
36
2
1
Clonality
Monoclonal
Conjugate
This TIE1 antibody is un-conjugated
7
5
5
5
4
2
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (IHC), Western Blotting (WB)
95
75
28
22
13
11
6
6
4
3
2
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

It's quick and easy to submit your validation proposal. I want to validate this product

Learn more

Available images

Catalog No. ABIN258833
Contact our Customer Service for availability and price in your country.
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.201695 ABIN2496736 IHC WB Rabbit Ig Fraction N-Term Log in to see Polyclonal
0.0011392047 ABIN289553 IF IHC ELISA WB Rabbit IgG Log in to see Polyclonal
0.0011392047 ABIN289554 IF IHC ELISA WB Rabbit IgG1 Log in to see Polyclonal
0.0011392047 ABIN1941873 IHC ELISA WB APC Rabbit IgG N-Term Log in to see Polyclonal
0.0011392047 ABIN1941874 IHC ELISA WB Biotin Rabbit IgG N-Term Log in to see Polyclonal
0.0011392047 ABIN1941875 IHC ELISA WB FITC Rabbit IgG N-Term Log in to see Polyclonal
0.0011392047 ABIN1941876 IHC ELISA WB PE Rabbit IgG N-Term Log in to see Polyclonal
0.0011392047 ABIN1941877 IHC ELISA WB HRP Rabbit IgG N-Term Log in to see Polyclonal
0.0011392047 ABIN1824787 IHC WB Rabbit IgG Log in to see Polyclonal
0.0011392047 ABIN2574437 IHC ELISA Rabbit IgG N-Term Log in to see Polyclonal
0.0011392047 ABIN2467205 IHC Rabbit IgG C-Term Log in to see Polyclonal
0.0011392047 ABIN927258 IHC WB Rabbit IgG Log in to see Polyclonal
0.0011392047 ABIN2683015 IHC ELISA WB Mouse IgG1 AA 385-607 Log in to see 8D12D2
0.0011392047 ABIN2683016 IHC ELISA WB Mouse IgG1 AA 385-607 Log in to see 8D12B10
0.0011392047 ABIN1982942 IHC WB Mouse IgG1 AA 22-760 Log in to see MM0017-12D9
0.0011392047 ABIN2375282 IHC ELISA WB Rabbit IgG AA 12-42, N-Term Log in to see Polyclonal
0.0011392047 ABIN2375284 IHC ELISA WB APC Rabbit IgG AA 12-42, N-Term Log in to see Polyclonal
0.0011392047 ABIN2375286 IHC ELISA WB FITC Rabbit IgG N-Term Log in to see Polyclonal
0.0011392047 ABIN2375287 IHC ELISA WB HRP Rabbit IgG N-Term Log in to see Polyclonal
0.0011392047 ABIN2375288 IHC ELISA WB PE Rabbit IgG N-Term Log in to see Polyclonal

Similar anti-TIE1 Antibodies

Application / Reactivity Human
ELISA 77 Antibodies
Enzyme Immunoassay (EIA) 6 Antibodies
Flow Cytometry (FACS) 13 Antibodies
Immunocytochemistry (ICC) 5 Antibodies
Immunofluorescence (IF) 3 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies
Immunohistochemistry (IHC) 29 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 2 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 23 Antibodies
Immunoprecipitation (IP) 4 Antibodies
Western Blotting (WB) 96 Antibodies

General

Antigen tyrosine Kinase with Immunoglobulin-Like and EGF-Like Domains 1 (TIE1) Antibodies
Epitope Extracellular Domain
(20), (17), (14), (13), (12), (11), (6), (5), (4), (4), (4), (3), (3), (3), (2), (2), (1)
Reactivity Human
(133), (41), (28), (2)
Host Mouse
(98), (36), (2), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This TIE1 antibody is un-conjugated
(7), (5), (5), (5), (4), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (IHC), Western Blotting (WB)
(95), (75), (28), (22), (13), (11), (6), (6), (4), (3), (2)
Supplier Log in to see

Product Details anti-TIE1 Antibody

Target Details TIE1 Application Details Handling Images
Specificity This antibody recognizes human Tie1 in western blot without cross reactivity with human Tie2. Reactivity to Tie1 of other species is not tested
Cross-Reactivity (Details) Not yet tested in other species.
Purification Protein G purified
Immunogen This antibody was produced from a hybridoma, mouse myeloma fused with spleen cells from a mouse immunized with hTie1 extracellular domain.
Clone MM0017-12D9
Isotype IgG1

Target Details TIE1

Product Details anti-TIE1 Antibody Application Details Handling Images back to top
Antigen
Alternative Name Tie-1 (TIE1 Antibody Abstract)
Background TIE1/TIE (tyrosine kinase with Ig and EGF homology domains 1) and TIE2/Tek define anew class of the receptor tyrosine kinase (RTK) subfamily with unique structuralcharacteristics: two immunoglobulin like domains flanking three epidermal growth factor(EFG) like domains followed by three fibronectin type III like repeats in the extracellularregion and a split tyrosine kinase domain in the cytoplasmic region. Human TIE1 cDNAencodes a 1138 amino acid residue precursor protein with a putative signal peptide, anextracellular domain, and a cytoplasmic domain. Human TIE1/Fc, a disulfide linkedhomodimeric protein, has a calculated molecular mass of approximately 107 kDa. Dueto glycosylation, the protein migrates to approximately 160 kDa in SDS PAGE underreducing conditions. TIE1 and TIE2, expressed primarily on endothelial andhematopoietic progenitor cells, play important roles in angiogenesis, vasculogenesis,and hematopoiesis. In developing vascular endothelial cells, TIE1 and TIE2 arespecifically expressed. Two ligands that bind TIE have been identified, angiopoietin 1and angiopoietin 2. Based on gene targeting studies, the in vivo functions of TIE1 arerelated to endothelial cell differentiation. The receptor tyrosine kinase TIE also plays arole in the survival and integrity of the endothelium. Alternate Names: Anti-JKT 14 antibody, Anti-JTK14 antibody, Anti-Tyrosine Kinase with Immunoglobulinand Epidermal Growth Factor Homology Domains antibody, Anti-Tyrosine protein kinasereceptor Tie 1 antibody.
Gene Symbol: TIE1
Gene ID 7075
Pathways RTK Signaling

Application Details

Product Details anti-TIE1 Antibody Target Details TIE1 Handling Images back to top
Application Notes Recommended dilutions: Immunohistochemistry 1:100-1:400, Immunohistochemistry-Paraffin 1:100-1:400, Western Blot 1:500-1:1000
Restrictions For Research Use only

Handling

Product Details anti-TIE1 Antibody Target Details TIE1 Application Details Images back to top
Format Lyophilized
Reconstitution Reconstitute in 500 µL of sterile PBS, final concentration 0.2 mg/mL.
Buffer Lyophilized from a 0.2 µm filtered solution in Phosphate-buffered saline (PBS).
Preservative Without preservative
Handling Advice Avoid freeze-thaw cycles
Storage -20 °C
Storage Comment Aliquot and store at -20 °C or -80 °C.

Images

Product Details anti-TIE1 Antibody Target Details TIE1 Application Details Handling back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-TIE1 antibody (tyrosine Kinase with Immunoglobulin-Like and EGF-Like Domains 1) (Extracellular Domain) (ABIN258833) anti-tyrosine Kinase with Immunoglobulin-Like and EGF-Like Domains 1 (TIE1) (Extracellular Domain) antibody
Immunohistochemistry (IHC) image for anti-TIE1 antibody (tyrosine Kinase with Immunoglobulin-Like and EGF-Like Domains 1) (Extracellular Domain) (ABIN258833) anti-tyrosine Kinase with Immunoglobulin-Like and EGF-Like Domains 1 (TIE1) (Extracellular Domain) antibody (Image 2)