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anti-Human TRKA antibody for Enzyme Immunoassay

Recommended TRKA Antibody (supplied by: Log in to see )

Antigen
Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1) Antibodies
  • C80751
  • CAPM1
  • CFTD
  • CTRKA
  • hscp30
  • MTC
  • NEM1
  • OK/SW-cl.5
  • p140-TrkA
  • Tkr
  • TM-5
  • TM3
  • TM5
  • TM30
  • TM30nm
  • TPMsk3
  • trk
  • TRK
  • Trk
  • Trk-A
  • TRK1
  • TRKA
  • TrkA
  • trkA
  • trka
Epitope
pTyr791
46
24
23
20
18
16
14
14
13
13
13
13
12
12
11
10
10
9
9
8
6
6
6
6
6
5
5
4
3
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
380
199
168
2
2
Host
Rabbit
358
50
4
3
2
Clonality
Polyclonal
Conjugate
This TRKA antibody is un-conjugated
16
15
15
10
8
8
8
8
7
7
7
7
7
7
7
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
249
153
90
76
54
46
39
33
19
14
5
3
1
1
Supplier
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Catalog No. ABIN358249
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008867729 ABIN453859 EIA WB Rabbit Tyr791 Log in to see Polyclonal 5
0.0008867729 ABIN359950 EIA WB Rabbit Ig Middle Region Log in to see Polyclonal 4
0.0008867729 ABIN272088 EIA IHC (p) WB Rabbit Log in to see Polyclonal

Top referenced anti-TRKA antibody for Enzyme Immunoassay

  • Human Polyclonal TRKA Primary Antibody for EIA, WB - ABIN453859 (5 Publications): Tokusashi, Asai, Tamakawa, Yamamoto, Yoshie, Yaginuma, Miyokawa, Aoki, Kino, Kasai, Ogawa: Expression of NGF in hepatocellular carcinoma cells with its receptors in non-tumor cell components. in International journal of cancer. Journal international du cancer 2005 (PubMed)

  • Human Polyclonal TRKA Primary Antibody for EIA, WB - ABIN359950 (4 Publications): Schulte, Schramm, Klein-Hitpass, Klenk, Wessels, Hauffa, Eils, Eils, Brodeur, Schweigerer, Havers, Eggert: Microarray analysis reveals differential gene expression patterns and regulation of single target genes contributing to the opposing phenotype of TrkA- and TrkB-expressing neuroblastomas. in Oncogene 2005 (PubMed)

  • Human Polyclonal TRKA Primary Antibody for EIA, WB - ABIN358249 (5 Publications): Tacconelli, Farina, Cappabianca, Desantis, Tessitore, Vetuschi, Sferra, Rucci, Argenti, Screpanti, Gulino, Mackay: TrkA alternative splicing: a regulated tumor-promoting switch in human neuroblastoma. in Cancer cell 2004 (PubMed)

Similar anti-TRKA Antibodies

Application / Reactivity Human
Dot Blot (DB) 19 Antibodies
ELISA 141 Antibodies
Enzyme Immunoassay (EIA) 4 Antibodies
Flow Cytometry (FACS) 34 Antibodies
Immunochromatography (IC) 4 Antibodies
Immunocytochemistry (ICC) 13 Antibodies
Immunofluorescence (IF) 55 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 76 Antibodies
Immunohistochemistry (IHC) 84 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 1 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 46 Antibodies
Immunoprecipitation (IP) 38 Antibodies
Neutralization (Neut) 1 Antibodies
Western Blotting (WB) 223 Antibodies

General

Antigen Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1) Antibodies
Epitope pTyr791
(46), (24), (23), (20), (18), (16), (14), (14), (13), (13), (13), (13), (12), (12), (11), (10), (10), (9), (9), (8), (6), (6), (6), (6), (6), (5), (5), (4), (3), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(380), (199), (168), (2), (2)
Host Rabbit
(358), (50), (4), (3), (2)
Clonality
Polyclonal
Conjugate This TRKA antibody is un-conjugated
(16), (15), (15), (10), (8), (8), (8), (8), (7), (7), (7), (7), (7), (7), (7), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Western Blotting (WB)
(249), (153), (90), (76), (54), (46), (39), (33), (19), (14), (5), (3), (1), (1)
Pubmed 5 references available
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Product Details anti-TRKA Antibody

Target Details TRKA Application Details Handling References for anti-TRKA Antibody (ABIN358249) Images
Specificity This antibody detects TrKA pTyr791.
Purification Protein G Affinity Chromatography. Then, the antibody fraction is peptide affinity purified in a 2-step procedure with control and phosphorylated peptides. The phospho-specific antibody is eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y791 of human TrkA.
Isotype Ig

Target Details TRKA

Product Details anti-TRKA Antibody Application Details Handling References for anti-TRKA Antibody (ABIN358249) Images back to top
Antigen
Alternative Name TrkA (NTRK1 Antibody Abstract)
Background TrkA is a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in the TrkA gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer.Synonyms: High affinity nerve growth factor receptor, NTRK1, Neurotrophic tyrosine kinase receptor type 1, TRK, TRK1-transforming tyrosine kinase protein, Trk-A, p140-TrkA
Molecular Weight 87511 Da
Gene ID 4914, 9606
UniProt P04629
Research Area Cancer
Pathways RTK Signaling, Neurotrophin Signaling Pathway

Application Details

Product Details anti-TRKA Antibody Target Details TRKA Handling References for anti-TRKA Antibody (ABIN358249) Images back to top
Application Notes ELISA: 1/1,000Western Blot: 1/100-1/500. Dot Blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-TRKA Antibody Target Details TRKA Application Details References for anti-TRKA Antibody (ABIN358249) Images back to top
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) Sodium Azide as preservative.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

References for anti-TRKA Antibody (ABIN358249)

Product Details anti-TRKA Antibody Target Details TRKA Application Details Handling Images back to top
Background publications

Tacconelli, Farina, Cappabianca, Desantis, Tessitore, Vetuschi, Sferra, Rucci, Argenti, Screpanti, Gulino, Mackay: "TrkA alternative splicing: a regulated tumor-promoting switch in human neuroblastoma." in: Cancer cell, Vol. 6, Issue 4, pp. 347-60, 2004

Frattini, Ferrario, Bressan, Balestra, De Cecco, Mondellini, Bongarzone, Collini, Gariboldi, Pilotti, Pierotti, Greco: "Alternative mutations of BRAF, RET and NTRK1 are associated with similar but distinct gene expression patterns in papillary thyroid cancer." in: Oncogene, Vol. 23, Issue 44, pp. 7436-40, 2004

Flørenes, Maelandsmo, Holm, Reich, Lazarovici, Davidson: "Expression of activated TrkA protein in melanocytic tumors: relationship to cell proliferation and clinical outcome." in: American journal of clinical pathology, Vol. 122, Issue 3, pp. 412-20, 2004

Woo, Lucarelli, Thiele: "NGF activation of TrkA decreases N-myc expression via MAPK path leading to a decrease in neuroblastoma cell number." in: Oncogene, Vol. 23, Issue 8, pp. 1522-30, 2004

Guo, Liao, Soong, Tsai, Niu, Lee, Lin: "Congenital insensitivity to pain with anhidrosis in Taiwan: a morphometric and genetic study." in: European neurology, Vol. 51, Issue 4, pp. 206-14, 2004

Images

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Supplier Images
 image for anti-TRKA antibody (Neurotrophic Tyrosine Kinase, Receptor, Type 1) (pTyr791) (ABIN358249) anti-Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1) (pTyr791) antibody