anti-Rat (Rattus) VEGFC antibody for Enzyme Immunoassay

Recommended VEGFC Antibody (supplied by: Log in to see )

Antigen
Vascular Endothelial Growth Factor C (VEGFC) Antibodies
  • VEGFC
  • vegf-c
  • xvegf-c
  • Flt4-L
  • VRP
  • AW228853
  • VEGF-C
  • vascular endothelial growth factor c
  • vascular endothelial growth factor C
  • vascular endothelial growth factor C-like
  • vegfc
  • VEGFC
  • Vegfc
  • LOC100525960
Reactivity
Human, Rat (Rattus)
242
91
77
3
3
2
2
1
1
1
1
1
Host
Mouse
171
121
8
1
Clonality
Monoclonal
Conjugate
This VEGFC antibody is un-conjugated
25
22
18
9
7
7
5
5
4
4
4
4
4
4
4
4
4
3
2
2
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
253
144
130
39
23
23
20
16
13
11
8
8
3
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Catalog No. ABIN360868
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN115678 EIA IP Rabbit Log in to see Polyclonal 1
1 ABIN115679 EIA IP Rabbit Log in to see Polyclonal
1 ABIN5540710 EIA Biotin Rabbit IgG AA 101-221 Log in to see Polyclonal

General

Antigen Vascular Endothelial Growth Factor C (VEGFC) Antibodies
Reactivity Human, Rat (Rattus)
(242), (91), (77), (3), (3), (2), (2), (1), (1), (1), (1), (1)
Host Mouse
(171), (121), (8), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This VEGFC antibody is un-conjugated
(25), (22), (18), (9), (7), (7), (5), (5), (4), (4), (4), (4), (4), (4), (4), (4), (4), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Western Blotting (WB)
(253), (144), (130), (39), (23), (23), (20), (16), (13), (11), (8), (8), (3)
Pubmed 2 references available
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Product Details anti-VEGFC Antibody

Target Details VEGFC Application Details Handling ProductDetails: References for anti-VEGFC antibody (ABIN360868) Images
Specificity This antibody detects VEGF-C in Western Blots. No cross-reactivity is shown with VEGF-A.
Purification Protein G Affinity Chromatography
Immunogen Recombinant Human VEGF-C protein (Cat.-No AR01001PU-N)
Clone 107F10
Isotype IgG2a

Target Details VEGFC

Product Details anti-VEGFC Antibody Application Details Handling ProductDetails: References for anti-VEGFC antibody (ABIN360868) Images back to top
Antigen
Alternative Name VEGF-C / Flt4-L (VEGFC Antibody Abstract)
Background VEGF-C, also known as Vascular Endothelial Growth Factor Related Protein (VRP), is a recently discovered VEGF growth factor family member that is most closely related to VEGF-D. The human VEGF-C cDNA encodes a pre-pro-protein of 416 amino acids residues. It is almost identical to the mouse VEGF-C protein. Similar to VEGF-D, VEGF-C has a VEGF homology domain spanning the middle third of the precursor molecule and long N- and C-terminal extensions. In adults, VEGF-C is highly expressed in heart, placenta, ovary and small intestine. Recombinant human VEGF-C, lacking the N- and C-terminal extensions and containing only the middle VEGF homology domain, forms primarily non-covalently linked dimers. This protein is a ligand for both VEGFR-2/KDR and VEGFR-3/FLT-4. Since VEGFR-3 is strongly expressed in lymphatic endothelial cells, it has been postulated that VEGF-C is involved in the regulation of the growth and/or differentiation of lymphatic endothelium. Although recombinant human VEGF-C is also a mitogen for vascular endothelial cells, it is much less potent than VEGF-A. The recombinant human VEGF-C contains 115 amino acids residues and was fused to a His-tag (6x His) at the C-terminal end. As a result of glycosylation VEGF-C migrates as an 18-24 kDa protein in SDS-PAGE under reducing conditions.Synonyms: Flt4 ligand, VEGFC, VRP, Vascular endothelial growth factor C, Vascular endothelial growth factor-related protein
Gene ID 7424
NCBI Accession NP_005420
UniProt P49767
Research Area Cytokines, Growth Factors, Receptors, Immunology, Inflammation, Signaling
Pathways RTK Signaling, Signaling Events mediated by VEGFR1 and VEGFR2

Application Details

Product Details anti-VEGFC Antibody Target Details VEGFC Handling ProductDetails: References for anti-VEGFC antibody (ABIN360868) Images back to top
Application Notes Western Blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-VEGFC Antibody Target Details VEGFC Application Details ProductDetails: References for anti-VEGFC antibody (ABIN360868) Images back to top
Reconstitution Restore in sterile water to a concentration of 0.1-1.0 mg/mL. Centrifuge vial prior to opening.
Buffer PBS without preservatives or stabilizers
Preservative Without preservative
Handling Advice Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Storage 4 °C/-20 °C
Storage Comment Prior to reconstitution store at 2-8 °C. Following reconstitution store at -20 °C. This product should be stored undiluted.

ProductDetails: References for anti-VEGFC antibody (ABIN360868)

Product Details anti-VEGFC Antibody Target Details VEGFC Application Details Handling Images back to top
Background publications

Olofsson, Jeltsch, Eriksson, Alitalo: "Current biology of VEGF-B and VEGF-C." in: Current opinion in biotechnology, Vol. 10, Issue 6, pp. 528-35, 2000

Joukov, Pajusola, Kaipainen, Chilov, Lahtinen, Kukk, Saksela, Kalkkinen, Alitalo: "A novel vascular endothelial growth factor, VEGF-C, is a ligand for the Flt4 (VEGFR-3) and KDR (VEGFR-2) receptor tyrosine kinases." in: The EMBO journal, Vol. 15, Issue 2, pp. 290-98, 1996