Browse our Nephroblastoma Overexpressed Proteins (NOV)

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Nephroblastoma Overexpressed Proteins (NOV)
On www.antibodies-online.com are 24 Nephroblastoma Overexpressed (NOV) Proteins from 9 different suppliers available. Additionally we are shipping Nephroblastoma Overexpressed Antibodies (90) and Nephroblastoma Overexpressed Kits (15) and many more products for this protein. A total of 143 Nephroblastoma Overexpressed products are currently listed.
Synonyms:
2600013D04Rik, C130088N23Rik, CCN3, IBP-9, IGFBP-9, IGFBP9, mKIAA4053, NOV, nov-A, NovH, PlexA1, Plxn1, xnov
list all proteins Gene Name GeneID UniProt
NOV 4856 P48745
NOV 81526 Q9QZQ5
NOV 18133 Q64299

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Nephroblastoma Overexpressed Proteins (NOV) by Origin

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Top referenced Nephroblastoma Overexpressed Proteins

  1. Human NOV Protein expressed in Wheat germ - ABIN1312819 : Janune, Kubota, Nishida, Kawaki, Perbal, Iida, Takigawa: Novel effects of CCN3 that may direct the differentiation of chondrocytes. in FEBS letters 2011 (PubMed)
    Show all 2 references for 1312819

More Proteins for Nephroblastoma Overexpressed Interaction Partners

Human Nephroblastoma Overexpressed (NOV) interaction partners

  1. Reduced levels of CCN1 (show CCNA2 Proteins) and CCN3, as found in early-onset preeclampsia, could contribute to a shift from invasive to proliferative extravillous trophoblasts and may explain their shallow invasion properties in this disease.

  2. our findings establish CCN3 as a pivotal regulator of androgen receptor (AR (show AR Proteins)) signaling and prostate cancer progression and suggest a functional intersection between EZH2 (show EZH2 Proteins) and AR signaling in castration-resistant prostate cancer

  3. The present study aimed to examine the clinical relevance of NOV along with CYR61 and CTGF in gastric cancer by analysing their transcript levels...the expression of NOV and CYR61 was increased in gastric cancer. The elevated expression of CYR61 was associated with poorer survival. NOV promoted proliferation and invasion of gastric cancer cells

  4. Studies indicate that the CYR61 (show CYR61 Proteins) CTGF (show CTGF Proteins) NOV matricellular proteins (CCN family of proteins) comprises the members CCN1 (show CCNA2 Proteins), CCN2 (show CTGF Proteins), CCN3, CCN4 (show WISP1 Proteins), CCN5 (show WISP2 Proteins) and CCN6 (show WISP3 Proteins) and have been identified in various types of cancer.

  5. NOV expression was highly increased in biopsies of patients with tubulointerstitial nephritis.

  6. Results revealed that NOV regulates the tumor growth of osteosarcoma cells through activation of the MAPK (show MAPK1 Proteins) signaling pathway and promotes osteosarcoma cell migration in vitro.

  7. our results argue that MZF-1 regulates the CTGF and NOV genes in the hematopoietic compartment, and may be involved in their respective functions in the stroma.

  8. Overexpression of CCN3 induces M2 macrophage infiltration and contributes to angiogenesis in prostate cancer microenvironment.

  9. NOV may promote carcinogenesis via promotion of EMT (show ITK Proteins) and association with increased mTOR (show FRAP1 Proteins) activity

  10. CCN3 can promote dentinogenesis by coordinating proliferation and odontoblastic differentiation of dental pulp stem cells via modulating Notch (show NOTCH1 Proteins) and BMP2 (show BMP2 Proteins) signaling pathways.

Mouse (Murine) Nephroblastoma Overexpressed (NOV) interaction partners

  1. Administration of EET alters Wnt1 (show WNT1 Proteins), NOV, and HO-1 (show HMOX1 Proteins) signaling to prevent obesity-induced cardiomyopathy in obese mice.

  2. PLXNA1 (show PLXNA1 Proteins) mediates the acquisition of malignant phenotypes induced by autocrine SEMA3A (show SEMA3A Proteins) signaling in lung cancer cells.

  3. results show that NOV is a new adipocytokine that could be involved in obesity-associated insulin (show INS Proteins)-resistance.

  4. Study showed that progenitor cells lining the telencephalic ventricles express PlexinA1 (show PLXNA1 Proteins) and that absence of this receptor impairs neurogenesis in the developing forebrain

  5. Genetic and pharmacological approaches implicated the ERK1/2 pathway as a critical regulator of CCN3-dependent AAA (show AAAS Proteins) development.

  6. Reduced NOV expression limits inflammation and interstitial renal fibrosis after obstructive nephropathy in mice.

  7. NOV is required for the maintenance of articular cartilage and for joint homeostasis, with disruption of NOV in ageing Nov(del3)-/- male mice causing osteoarthritis-like disease.

  8. tight regulation of CCN3 expression is necessary for normal cortical neuronal connectivity during development, and RAB25 (show RAB25 Proteins) negatively regulates neuronal differentiation as a downstream effector of CCN3

  9. CCN3 overexpression is associated with control of inflammatory processes and reversion of dyslipidemia in the process of atherosclerosis, which implies that CCN3 may be a promising target in the treatment of atherosclerosis.

  10. PlexinA1 (show PLXNA1 Proteins) mediates both Semaphorin and Slit signaling

Nephroblastoma Overexpressed (NOV) Protein Profile

Protein Summary

The protein encoded by this gene is a small secreted cysteine-rich protein and a member of the CCN family of regulatory proteins. CNN family proteins associate with the extracellular matrix and play an important role in cardiovascular and skeletal development, fibrosis and cancer development.

Alternative names and synonyms associated with Nephroblastoma Overexpressed (NOV)

  • nephroblastoma overexpressed (NOV)
  • nephroblastoma overexpressed (Nov)
  • nephroblastoma overexpressed (nov)
  • nephroblastoma overexpressed gene (NOV)
  • nephroblastoma overexpressed gene (Nov)
  • plexin A1 (Plxna1)
  • 2600013D04Rik protein
  • C130088N23Rik protein
  • CCN3 protein
  • IBP-9 protein
  • IGFBP-9 protein
  • IGFBP9 protein
  • mKIAA4053 protein
  • NOV protein
  • nov-A protein
  • NovH protein
  • PlexA1 protein
  • Plxn1 protein
  • xnov protein

Protein level used designations for NOV

CCN family member 3 , IGF-binding protein 9 , insulin-like growth factor-binding protein 9 , nephroblastoma-overexpressed gene protein homolog , protein NOV homolog , nephroblastoma overexpressed gene protein homolog , novH , nephroblastoma overexpressed gene protein , nephroblastoma-overexpressed gene protein , protein NOV , plex 1 , plexin 1 , plexin-1 , plexin-A1

GENE ID SPECIES
4856 Homo sapiens
81526 Rattus norvegicus
373662 Xenopus laevis
475083 Canis lupus familiaris
505727 Bos taurus
18133 Mus musculus
396204 Gallus gallus
18844 Mus musculus
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