Browse our anti-SMAD, Mothers Against DPP Homolog 1 (SMAD1) Antibodies

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anti-SMAD, Mothers Against DPP Homolog 1 Antibodies (SMAD1)
On www.antibodies-online.com are 330 SMAD, Mothers Against DPP Homolog 1 (SMAD1) Antibodies from 31 different suppliers available. Additionally we are shipping SMAD, Mothers Against DPP Homolog 1 Kits (53) and SMAD, Mothers Against DPP Homolog 1 Proteins (22) and many more products for this protein. A total of 424 SMAD, Mothers Against DPP Homolog 1 products are currently listed.
Synonyms:
2/23, AI528653, apg, BSP-1, BSP1, c28, CG12399, dMad, Dmel\\CG12399, E(zen)2, En(vvl), fb39h09, JV4-1, JV41, l(2)k00237, mad, Madh1, Madr1, Mat, MLP, Mlp1, MusMLP, p-Mad, pMad, pSmad, Smad, smad-1, smad1, wu:fb39h09, wu:fb97e04, xmad, Xmad1, Xsmad1
list all antibodies Gene Name GeneID UniProt
SMAD1 4086 Q15797
SMAD1 17125 P70340
Anti-Rat SMAD1 SMAD1 25671  

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Top referenced anti-SMAD, Mothers Against DPP Homolog 1 Antibodies

  1. Human Monoclonal SMAD1 Primary Antibody for IF, WB - ABIN393492 : Jugessur, Shi, Gjessing, Lie, Wilcox, Weinberg, Christensen, Boyles, Daack-Hirsch, Nguyen, Christiansen, Lidral, Murray: Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia. in PLoS ONE 2010 (PubMed)
    Show all 5 references for 393492

  2. Human Polyclonal SMAD1 Primary Antibody for WB - ABIN1881815 : Ye, Yu, Hu, Lu, Xie: Alterations of dendritic cell subsets in the peripheral circulation of patients with cervical carcinoma. in Journal of experimental & clinical cancer research : CR 2010 (PubMed)
    Show all 4 references for 1881815

  3. Human Polyclonal SMAD1 Primary Antibody for IF, WB - ABIN319351 : Li, Xin, Xu, Huang, Zhang, Chen, Zhang, Fu, Chang: CHIP mediates degradation of Smad proteins and potentially regulates Smad-induced transcription. in Molecular and cellular biology 2003 (PubMed)
    Show all 3 references for 319351

  4. Human Polyclonal SMAD1 Primary Antibody for WB - ABIN319257 : Nourry, Maksumova, Pang, Liu, Wang: Direct interaction between Smad3, APC10, CDH1 and HEF1 in proteasomal degradation of HEF1. in BMC cell biology 2004 (PubMed)
    Show all 3 references for 319257

  5. Human Polyclonal SMAD1 Primary Antibody for ELISA, WB - ABIN1533926 : Liu, Hata, Baker, Doody, Cárcamo, Harland, Massagué: A human Mad protein acting as a BMP-regulated transcriptional activator. in Nature 1996 (PubMed)
    Show all 2 references for 1533926

  6. Human Polyclonal SMAD1 Primary Antibody for IHC, ELISA - ABIN1532214 : Hoodless, Haerry, Abdollah, Stapleton, OConnor, Attisano, Wrana: MADR1, a MAD-related protein that functions in BMP2 signaling pathways. in Cell 1996 (PubMed)
    Show all 2 references for 1532214

  7. Cow (Bovine) Polyclonal SMAD1 Primary Antibody for WB - ABIN2779411 : Blount, Merlie: BIP associates with newly synthesized subunits of the mouse muscle nicotinic receptor. in The Journal of cell biology 1991 (PubMed)
    Show all 2 references for 2779411

  8. Cow (Bovine) Polyclonal SMAD1 Primary Antibody for WB - ABIN2780720 : Jadlowiec, Zhang, Li, Campbell, Sfeir: Extracellular matrix-mediated signaling by dentin phosphophoryn involves activation of the Smad pathway independent of bone morphogenetic protein. in The Journal of biological chemistry 2006 (PubMed)

More Antibodies against SMAD, Mothers Against DPP Homolog 1 Interaction Partners

Zebrafish SMAD, Mothers Against DPP Homolog 1 (SMAD1) interaction partners

  1. Data show that interplay of Smad1/5 and MAP kinase (show MAPK1 Antibodies) signaling system (ERK (show MAPK1 Antibodies) signalling) is essential for haemogenic endothelium-based haematopoietic stem cell emergence.

  2. this study uncovers that smad1 and smad9 (show SMAD9 Antibodies) act redundantly to each other downstream of smad5 (show SMAD5 Antibodies) to mediate ventral specification and to regulate embryonic myelopoiesis.

  3. that specificity of BMP signaling output, with respect to hematopoiesis, can be explained by differential functions of Smad1 and Smad5 (show SMAD5 Antibodies).

Fruit Fly (Drosophila melanogaster) SMAD, Mothers Against DPP Homolog 1 (SMAD1) interaction partners

  1. we identify key roles for the Zelda and Zerknullt transcription factors in establishing the resulting expression domain, and find widespread binding of insulator proteins to the Mad and Brinker-bound genomic regions. Analysis of embryos lacking the BEAF-32 insulator protein shows reduced transcription of a peak BMP target gene and a reduction in the number of amnioserosa cells, the fate specified by peak BMP signaling.

  2. Mad linker phosphorylations control the intensity and range of the BMP-activity gradient in developing Drosophila tissues.

  3. During development, synaptic pMad accumulation followed the arrival and clustering of ionotropic glutamate (show GRIN2A Antibodies) receptors at neuromuscular junction synapses.

  4. The actions of Brat at synapses are mediated through mothers against decapentaplegic (Mad), the signal transduction effector of the bone morphogenetic protein (BMP) signaling pathway.

  5. Mad has distinct signal transduction roles in the BMP (show TGFb Antibodies) and Wnt (show WNT4 Antibodies) pathways depending on its phosphorylation state.

  6. Yorkie (show YAP1 Antibodies) and Mad physically bind each other, and 410 bp minimal enhancer of bantam that responds to Yorkie:Mad in vivo and in cultured cells, was identified.

  7. Heterodimers of SAX and TKV play an important role in extending the BMP activity gradient by facilitating DPP diffusion and assisting GBB signaling through functional complexes with type II receptors.

  8. importin (show KPNA4 Antibodies)-beta11 function interacts with the bone morphogenic protein (show TGFb Antibodies) pathway to regulate a pool of phosphorylated mothers against decapentaplegic that must be present at the presynapse for its proper development and function

  9. Mad depletion or overexpression produced Wingless-like embryonic segmentation phenotypes

  10. The downstream transcription factor Mothers against dpp is essential for the normal structural and functional development of the Drosophila neuromuscular junction, a synapse that displays activity-dependent plasticity.

Human SMAD, Mothers Against DPP Homolog 1 (SMAD1) interaction partners

  1. Store operated calcium entry negatively regulates the Smad1 (show GARS Antibodies) signaling pathway and inhibits Col (show HDAC1 Antibodies) IV protein production in glomerular mesangial cells.

  2. A significant association was found between the low expression of inhibitory protein SMAD-7 (show SMAD7 Antibodies) and both zeta-chain-associated protein kinase (show CDK7 Antibodies) 70-negative cells (p = 0.04) and lower apoptotic index (p = 0.004). No differences were observed in SMAD-2 (show SMAD2 Antibodies)/3 expression. In conclusion, our results demonstrate a significant correlation between greater SMAD-1 (show GARS Antibodies)/8 and lower SMAD-4 (show SMAD4 Antibodies) expression in chronic lymphocytic leukemia cells

  3. melatonin treatment was found to downregulate TNFalpha (show TNF Antibodies)-induced SMURF1 (show SMURF1 Antibodies) expression and then decrease SMURF1 (show SMURF1 Antibodies)-mediated ubiquitination and degradation of SMAD1 (show GARS Antibodies) protein

  4. The expression of specific targets Smad1 (show GARS Antibodies) and Osterix (show SP7 Antibodies) was significantly increased in the presence of Pi and restored by coincubation with Mg(2 (show MUC7 Antibodies)+). As miR (show MLXIP Antibodies)-30b, miR (show MLXIP Antibodies)-133a, and miR (show MLXIP Antibodies)-143 are negatively regulated by Pi and restored by Mg(2 (show MUC7 Antibodies)+) with a congruent modulation of their known targets Runx2 (show RUNX2 Antibodies), Smad1 (show GARS Antibodies), and Osterix (show SP7 Antibodies), our results provide a potential mechanistic explanation of the observed upregulation of these master switches of o

  5. the BMP-2 (show BMP2 Antibodies)/Smad1 (show GARS Antibodies)/5/RUNX2 (show RUNX2 Antibodies) signaling pathway participates in the silicon-mediated induction of COL-1 and osteocalcin (show BGLAP Antibodies) synth

  6. Regulation of impaired angiogenesis in diabetic dermal wound healing by microRNA-26a is mediated by the increased expression of its target gene, SMAD1 (show GARS Antibodies).

  7. The expression SMAD1 (show GARS Antibodies) protein showed a significant correlation with lung cancer differentiation and lymphatic metastasis (P < 0.05), but not with genders, ages, tumor sizes and histological types of lung cancer patients (P>0.05).

  8. Overexpression of Smad1 (show GARS Antibodies) is associated with prostate cancer.

  9. SMAD1 (show GARS Antibodies) signaling may be a key pathway contributing the pathogenesis of Cardio-facio-cutaneous syndrome during early development.

  10. Smad1 (show GARS Antibodies) elevation serves as a compensatory mechanism for p53 (show TP53 Antibodies) deficiency by potentiating the activation of p53 (show TP53 Antibodies) parallel pathways.

Mouse (Murine) SMAD, Mothers Against DPP Homolog 1 (SMAD1) interaction partners

  1. these results identify a novel function of YAP (show YAP1 Antibodies) in neocortical astrocytic differentiation and proliferation, and reveal a BMP2 (show BMP2 Antibodies)-YAP (show YAP1 Antibodies)-SMAD1 pathway underlying astrocytic differentiation in the developing mouse neocortex.

  2. Dynamin (show DNM1 Antibodies)-dependent endocytosis of Bone Morphogenetic Protein2 (BMP2 (show BMP2 Antibodies)) and its receptors is dispensable for the initiation of Smad signaling

  3. Thyroid-specific Smad1 and Smad5 (show SMAD5 Antibodies) double-knockout (Smad1/5(dKO)) mice displayed growth retardation, hypothyroidism and defective follicular architecture.

  4. Smad1 and Smad5 (show SMAD5 Antibodies) have overlapping functions to govern hepcidin (show HAMP Antibodies) transcription. Moreover, erythropoietin (show EPO Antibodies) and erythroferrone target Smad1/5 signaling and require Smad1/5 to suppress hepcidin (show HAMP Antibodies) expression.

  5. Actin cytoskeleton depolymerization inhibites BMP2 (show BMP2 Antibodies) signaling via blocking of Smad by dephosphorylated CNN1 (show CNN1 Antibodies) in osteoblast cells under simulated microgravity.

  6. Store operated calcium entry negatively regulates the Smad1 signaling pathway and inhibits Col (show HDAC1 Antibodies) IV protein production in glomerular mesangial cells.

  7. Thus, our findings identify an unrecognized function of neogenin (show NEO1 Antibodies) in mouse neocortical astrocyte differentiation, and suggest a signaling pathway, BMP2 (show BMP2 Antibodies)-neogenin (show NEO1 Antibodies)-YAP (show YAP1 Antibodies)-Smad1, underlying astrogliogenesis in developing mouse neocortex.

  8. Collectively, the data suggest that Cytl1 (show CYTL1 Antibodies) plays an essential role in cardiac fibrosis likely through activating the TGF-beta (show TGFB1 Antibodies)-SMAD signaling pathway.

  9. BetA can enhance in vivo osteogenic potentials of BMP2 (show BMP2 Antibodies), possibly via stimulating Smad 1/5/8 and p38 (show CRK Antibodies) pathways, and combination of both agents can be considered as a therapeutic strategy for bone diseases.

  10. Mutant GDF5 (show GDF5 Antibodies) enhances ameloblast differentiation via accelerated BMP2 (show BMP2 Antibodies)-induced Smad1-Smad5 (show SMAD5 Antibodies)-Smad8 (show SMAD9 Antibodies) phosphorylation.

Xenopus laevis SMAD, Mothers Against DPP Homolog 1 (SMAD1) interaction partners

  1. interactions between miR (show MYLIP Antibodies)-26 and the Smad1 3'UTR (show UTS2R Antibodies) modulate Smad1 function in the establishment of axial patterning.

Cow (Bovine) SMAD, Mothers Against DPP Homolog 1 (SMAD1) interaction partners

  1. a detailed computational model for TGF-beta (show TGFB1 Antibodies) signalling that incorporates elements of previous models together with crosstalking between Smad1/5/8 and Smad2 (show SMAD2 Antibodies)/3 channels through a negative feedback loop dependent on Smad7 (show SMAD7 Antibodies).

SMAD, Mothers Against DPP Homolog 1 (SMAD1) Antigen Profile

Antigen Summary

The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-mediated degradation. Alternatively spliced transcript variants encoding the same protein have been observed.

Alternative names and synonyms associated with SMAD, Mothers Against DPP Homolog 1 (SMAD1)

  • SMAD family member 1 (smad1) antibody
  • SMAD family member 1 (SMAD1) antibody
  • MAD homolog 1 (Drosophila) (smad1) antibody
  • Mothers against dpp (Mad) antibody
  • SMAD family member 1 (Smad1) antibody
  • SMAD family member 1 (smad1-a) antibody
  • 2/23 antibody
  • AI528653 antibody
  • apg antibody
  • BSP-1 antibody
  • BSP1 antibody
  • c28 antibody
  • CG12399 antibody
  • dMad antibody
  • Dmel\\CG12399 antibody
  • E(zen)2 antibody
  • En(vvl) antibody
  • fb39h09 antibody
  • JV4-1 antibody
  • JV41 antibody
  • l(2)k00237 antibody
  • mad antibody
  • Madh1 antibody
  • Madr1 antibody
  • Mat antibody
  • MLP antibody
  • Mlp1 antibody
  • MusMLP antibody
  • p-Mad antibody
  • pMad antibody
  • pSmad antibody
  • Smad antibody
  • smad-1 antibody
  • smad1 antibody
  • wu:fb39h09 antibody
  • wu:fb97e04 antibody
  • xmad antibody
  • Xmad1 antibody
  • Xsmad1 antibody

Protein level used designations for SMAD1

MAD homolog 1 , SMAD, mothers against DPP homolog 1 , mothers against decapentaplegic homolog 1 , mothers against decapentaplegic-like protein 1 , MAD (mothers against decapentaplegic, Drosophila) homolog 1 , SMA- and MAD-related protein 1 , SMAD 1 , SMAD family member 1 , mothers against DPP homolog 1 , CG12399-PA , CG12399-PB , Mad-PA , Mad-PB , apang , mother against decapentaplegic , mothers against decapentaplegi , mothers against decapentaplegic , mothers against dpp , phospho-Smad , phosphoSmad , phosphorylated smad , MAD, mothers against decapentaplegic homolog 1 , Mad-related protein 1 , TGF-beta signaling protein 1 , transforming growth factor-beta signaling protein 1 , transforming growth factor-beta-signaling protein 1 , Smad 1 , dwarfin-A , dwf-A , mMad1 , mad-related protein 1 , mothers-against-DPP-related 1 , MAD homolog1 (mothers against decapentaplegic, Drosophila) , mothers against DPP , BMP pathway effector , BMP signal transducer Smad1 , Sma- and Mad-related protein 1

GENE ID SPECIES
493211 Xenopus (Silurana) tropicalis
574340 Macaca mulatta
30628 Danio rerio
33529 Drosophila melanogaster
4086 Homo sapiens
17125 Mus musculus
25671 Rattus norvegicus
379664 Xenopus laevis
395680 Gallus gallus
475456 Canis lupus familiaris
397016 Sus scrofa
540488 Bos taurus
450142 Pan troglodytes
100432108 Pongo abelii
100033850 Equus caballus
443229 Ovis aries
100341544 Oryctolagus cuniculus
100727257 Cavia porcellus
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