anti-Mouse (Murine) CD4 antibody for ELISA (Capture)

Recommended CD4 Antibody (supplied by: Log in to see )

Antigen
CD4 Molecule (CD4) Antibodies
  • cd4
  • L3T4
  • Ly-4
  • CD4mut
  • W3/25
  • p55
  • CD4 molecule
  • CD4 antigen
  • T-cell surface glycoprotein CD4
  • Cd4 molecule
  • CD4
  • cd4
  • Cd4
Reactivity
Mouse (Murine)
1251
655
235
78
68
41
36
28
27
26
22
21
19
16
15
15
13
10
10
9
7
6
5
5
5
4
4
3
3
3
3
2
2
2
2
2
1
1
1
1
Host
Rat
1422
610
283
16
6
1
1
1
Clonality
Monoclonal
Conjugate
This CD4 antibody is conjugated to APC-Cy7
264
232
170
108
54
54
54
48
36
34
34
33
30
26
22
21
21
20
19
18
18
18
18
18
16
15
15
13
13
9
9
8
8
6
5
5
4
4
4
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Application
ELISA (Capture), Immunofluorescence (IF), Immunoprecipitation (IP), Western Blotting (WB)
1823
495
452
353
323
310
161
155
98
78
41
39
38
30
30
25
18
14
14
11
9
9
6
6
5
4
3
3
3
2
2
2
2
2
2
1
1
1
1
1
1
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Catalog No. ABIN2660685
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN2660686 ELISA (Capture) IF IP WB APC-Cy7 Rat IgG2a kappa Log in to see RM4-5 8

General

Antigen CD4 Molecule (CD4) Antibodies
Reactivity Mouse (Murine)
(1251), (655), (235), (78), (68), (41), (36), (28), (27), (26), (22), (21), (19), (16), (15), (15), (13), (10), (10), (9), (7), (6), (5), (5), (5), (4), (4), (3), (3), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Host Rat
(1422), (610), (283), (16), (6), (1), (1), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This CD4 antibody is conjugated to APC-Cy7
(264), (232), (170), (108), (54), (54), (54), (48), (36), (34), (34), (33), (30), (26), (22), (21), (21), (20), (19), (18), (18), (18), (18), (18), (16), (15), (15), (13), (13), (9), (9), (8), (8), (6), (5), (5), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application ELISA (Capture), Immunofluorescence (IF), Immunoprecipitation (IP), Western Blotting (WB)
(1823), (495), (452), (353), (323), (310), (161), (155), (98), (78), (41), (39), (38), (30), (30), (25), (18), (14), (14), (11), (9), (9), (6), (6), (5), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Pubmed 8 references available
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Product Details anti-CD4 Antibody

Target Details CD4 Application Details Handling References for anti-CD4 antibody (ABIN2660685) Images
Purification The antibody was purified by affinity chromatography, and conjugated with APC/Cy7 under optimal conditions. The solution is free of unconjugated APC/Cy7 and unconjugated antibody.
Clone RM4-5
Isotype IgG2a kappa

Target Details CD4

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Antigen
Alternative Name CD4 (CD4 Antibody Abstract)
Background CD4 is a 55 kD protein also known as L3T4 or T4. It is a member of the Ig superfamily, primarily expressed on most thymocytes and a subset of T cells, and weakly on macrophages and dendritic cells. It acts as a co-receptor with the TCR during T cell activation and thymic differentiation by binding MHC class II and associating with the protein tyrosine kinase lck.
Research Area Immunology, Adaptive Immunity, Hematopoietic Progenitors, CD Antigens, Surface Receptors of Immune Cells
Pathways TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events

Application Details

Product Details anti-CD4 Antibody Target Details CD4 Handling References for anti-CD4 antibody (ABIN2660685) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-CD4 Antibody Target Details CD4 Application Details References for anti-CD4 antibody (ABIN2660685) Images back to top
Concentration 0.2 mg/mL
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Protect from prolonged exposure to light. Do not freeze.
Storage 4 °C
Storage Comment The antibody solution should be stored undiluted between 2°C and 8°C.

References for anti-CD4 antibody (ABIN2660685)

Product Details anti-CD4 Antibody Target Details CD4 Application Details Handling Images back to top
Background publications

Zaborsky, Brunner, Wallner, Himly, Karl, Schwarzenbacher, Ferreira, Achatz: "Antigen aggregation decides the fate of the allergic immune response." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 184, Issue 2, pp. 725-35, 2010

Shigeta, Matsumoto, Tedder, Lowe, Miyasaka, Hirata: "An L-selectin ligand distinct from P-selectin glycoprotein ligand-1 is expressed on endothelial cells and promotes neutrophil rolling in inflammation." in: Blood, Vol. 112, Issue 13, pp. 4915-23, 2008

León-Ponte, Ahern, OConnell: "Serotonin provides an accessory signal to enhance T-cell activation by signaling through the 5-HT7 receptor." in: Blood, Vol. 109, Issue 8, pp. 3139-46, 2007

Matsumoto, Shigeta, Furukawa, Tanaka, Miyasaka, Hirata: "CD43 collaborates with P-selectin glycoprotein ligand-1 to mediate E-selectin-dependent T cell migration into inflamed skin." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 178, Issue 4, pp. 2499-506, 2007

Muraille, De Trez, Pajak, Torrentera, De Baetselier, Leo, Carlier: "Amastigote load and cell surface phenotype of infected cells from lesions and lymph nodes of susceptible and resistant mice infected with Leishmania major." in: Infection and immunity, Vol. 71, Issue 5, pp. 2704-15, 2003

Fan, Kouda, Nakamura, Takeuchi: "Effects of dietary restriction on spontaneous dermatitis in NC/Nga mice." in: Experimental biology and medicine (Maywood, N.J.), Vol. 226, Issue 11, pp. 1045-50, 2001

Janeway: "The T cell receptor as a multicomponent signalling machine: CD4/CD8 coreceptors and CD45 in T cell activation." in: Annual review of immunology, Vol. 10, pp. 645-74, 1992

Bierer, Sleckman, Ratnofsky, Burakoff: "The biologic roles of CD2, CD4, and CD8 in T-cell activation." in: Annual review of immunology, Vol. 7, pp. 579-99, 1989

Images

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Supplier Images
Flow Cytometry (FACS) image for anti-CD4 Molecule (CD4) antibody (APC-Cy7) (ABIN2660685) anti-CD4 Molecule (CD4) antibody (APC-Cy7)