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anti-Mouse (Murine) CD4 antibody for Immunohistochemistry (Frozen Sections)

Recommended CD4 Antibody (supplied by: Log in to see )

Antigen
CD4 Molecule (CD4) Antibodies
  • cd4
  • CD4mut
  • L3T4
  • Ly-4
  • p55
  • W3/25
Reactivity
Mouse (Murine)
1198
693
240
69
52
45
25
23
22
21
19
15
14
12
9
8
7
7
7
7
6
5
5
5
3
2
2
2
1
1
1
Host
Rat
1362
666
276
4
2
1
Clonality
Monoclonal
Conjugate
This CD4 antibody is un-conjugated
284
239
176
114
44
42
42
39
39
38
36
32
26
24
22
22
21
20
19
19
19
19
19
16
15
13
9
8
8
8
7
7
5
5
4
4
4
3
3
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Application
Functional Studies (Func), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
1808
436
399
355
309
300
179
136
100
69
33
28
28
27
22
18
14
11
10
9
7
6
6
6
5
5
4
3
2
2
2
2
2
2
1
1
1
1
1
1
1
Supplier
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Catalog No. ABIN118113
$ 621.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.000883884 ABIN118115 FACS IHC (fro) Rat IgG2b Log in to see YTS191-1 15
0.000883884 ABIN614792 Func IHC (fro) FACS IF IP Rat IgG2b Log in to see GK1-5 7
0.000883884 ABIN343704 Func ICC FACS IHC (fro) IP Rat IgG2b Extracellular Log in to see GK1-5 10
0.000883884 ABIN509566 Func ICC FACS IHC (fro) IP FITC Rat IgG2b Extracellular Log in to see GK1-5 9
0.000883884 ABIN255884 FACS IHC (fro) IHC Rat IgG2b Log in to see YTS191-1
0.000883884 ABIN1176974 BR IHC (fro) FACS IP Rat IgG2b, kappa Log in to see GK1-5 9
0.000883884 ABIN2689240 IHC (fro) FACS Biotin Rat IgG2b, kappa Log in to see GK1-5 7
0.000883884 ABIN1176846 BR CyTox IHC (f) IHC (fro) FACS IHC (zinc) IP Rat IgG2a, kappa Log in to see H129-19 14
0.000883884 ABIN2689230 IHC (f) IHC (fro) FACS IHC (zinc) Rat IgG2a, kappa Log in to see RM4 6
0.000883884 ABIN2689231 BR IHC (f) IHC (fro) FACS IHC (zinc) IP Rat IgG2a, kappa Log in to see H129-19 9
0.000883884 ABIN319535 FACS IHC (fro) Rat IgG2b Log in to see YTS191-1
0.000883884 ABIN317082 FACS IHC (fro) Rat IgG2a Log in to see RM4-5
0.000883884 ABIN476176 FACS IHC (fro) Rat IgG2a, kappa Log in to see RM4-5
0.000883884 ABIN476240 FACS IHC (fro) Rat IgG2b, kappa Log in to see GK1-5
0.000883884 ABIN286351 FACS IHC (fro) IP Biotin Rat IgG2b kappa Log in to see GK1-5
0.000883884 ABIN133263 FACS IHC (fro) Biotin Rat IgG2a Log in to see CT-CD4
0.000883884 ABIN133264 FACS IHC (fro) Biotin Rat IgG2a Log in to see CT-CD4
0.000883884 ABIN2480261 IHC (fro) FACS IF IP ELISA WB Rat IgG2b Log in to see GK1-5 4
0.000883884 ABIN2689225 BR IHC (f) IHC (fro) FACS IHC (zinc) IP Rat IgG2a, kappa Log in to see H129-19 15
0.000883884 ABIN2689224 IHC (f) IHC (fro) FACS IHC (zinc) IP Rat IgG2a, kappa Log in to see RM4 13

Top referenced anti-CD4 antibody for Immunohistochemistry (Frozen Sections)

Similar anti-CD4 Antibodies

Application / Reactivity Mouse (Murine)
Biochemical Assay (BCA) 3 Antibodies
Blocking Reagent (BR) 15 Antibodies
Cytotoxicity Test (CyTox) 7 Antibodies
Depletion (Dep) 2 Antibodies
ELISA 50 Antibodies
ELISA (Capture) 2 Antibodies
Enzyme Immunoassay (EIA) 3 Antibodies
Flow Cytometry (FACS) 565 Antibodies
Functional Studies (Func) 29 Antibodies
Immunochromatography (IC) 2 Antibodies
Immunocytochemistry (ICC) 40 Antibodies
Immunofluorescence (IF) 69 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 22 Antibodies
Immunohistochemistry (IHC) 105 Antibodies
Immunohistochemistry (Acetone-fixed) (IHC (af)) 10 Antibodies
Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) 7 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 94 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 18 Antibodies
Immunohistochemistry (Zinc-fixed Sections) (IHC (zinc)) 5 Antibodies

General

Antigen CD4 Molecule (CD4) Antibodies
Reactivity Mouse (Murine)
(1198), (693), (240), (69), (52), (45), (25), (23), (22), (21), (19), (15), (14), (12), (9), (8), (7), (7), (7), (7), (6), (5), (5), (5), (3), (2), (2), (2), (1), (1), (1)
Host Rat
(1362), (666), (276), (4), (2), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This CD4 antibody is un-conjugated
(284), (239), (176), (114), (44), (42), (42), (39), (39), (38), (36), (32), (26), (24), (22), (22), (21), (20), (19), (19), (19), (19), (19), (16), (15), (13), (9), (8), (8), (8), (7), (7), (5), (5), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Functional Studies (Func), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
(1808), (436), (399), (355), (309), (300), (179), (136), (100), (69), (33), (28), (28), (27), (22), (18), (14), (11), (10), (9), (7), (6), (6), (6), (5), (5), (4), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Pubmed 3 references available
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Product Details anti-CD4 Antibody

Target Details CD4 Application Details Handling References for anti-CD4 Antibody (ABIN118113) Images
Specificity This antibody recognises the CD4 cell surface antigen, expressed by a subset of T lymphocytes. This clone exhibits depleting activity when used in vivo.
Purification Affinity chromatography on Protein G
Endotoxin Level Low Endotoxin
Clone YTS191-1
Isotype IgG2b

Target Details CD4

Product Details anti-CD4 Antibody Application Details Handling References for anti-CD4 Antibody (ABIN118113) Images back to top
Antigen
Alternative Name CD4 (CD4 Antibody Abstract)
Background CD4, a single chain transmembrane glycoprotein, is found on a T cell subset (helper/inducer) representing 45 % of peripheral blood lymphocytes. It is also present on 80 % of thymocytes and at a lower level on monocytes. It is involved in recognition of antigen presented along with MHC class II by APCs. It serves as receptor for HIV.Synonyms: T-cell surface antigen T4/Leu-3, T-cell surface glycoprotein CD4
Gene ID 12504
NCBI Accession NP_038516
UniProt P06332
Research Area Immunology, Adaptive Immunity, Hematopoietic Progenitors, CD Antigens, Surface Receptors of Immune Cells
Pathways TCR Signaling

Application Details

Product Details anti-CD4 Antibody Target Details CD4 Handling References for anti-CD4 Antibody (ABIN118113) Images back to top
Application Notes Flow Cytometry: use 10 μL of 1/100-1/200 diluted antibody to label 10^6 cells in 100 μL. Immunohistochemistry on Frozen Sections. Functional asssays.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-CD4 Antibody Target Details CD4 Application Details References for anti-CD4 Antibody (ABIN118113) Images back to top
Concentration 1.0 mg/mL
Buffer PBS, pH 7.4 without preservatives.
Preservative Without preservative
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

References for anti-CD4 Antibody (ABIN118113)

Product Details anti-CD4 Antibody Target Details CD4 Application Details Handling Images back to top
Background publications

Higgins, McDonald, Whittle, Crockett, Shields, MacDonald et al.: "Regulation of T cell activation in vitro and in vivo by targeting the OX40-OX40 ligand interaction: amelioration of ongoing inflammatory bowel disease with an OX40-IgG fusion protein, but not with an ..." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 162, Issue 1, pp. 486-93, 1999

Bemelman, Honey, Adams, Cobbold, Waldmann: "Bone marrow transplantation induces either clonal deletion or infectious tolerance depending on the dose." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 160, Issue 6, pp. 2645-8, 1998

Cobbold, Martin, Waldmann: "The induction of skin graft tolerance in major histocompatibility complex-mismatched or primed recipients: primed T cells can be tolerized in the periphery with anti-CD4 and anti-CD8 antibodies." in: European journal of immunology, Vol. 20, Issue 12, pp. 2747-55, 1991

Images

Product Details anti-CD4 Antibody Target Details CD4 Application Details Handling References for anti-CD4 Antibody (ABIN118113) back to top
Supplier Images
Flow Cytometry (FACS) image for anti-CD4 antibody (CD4 Molecule) (ABIN118113) Staining of mouse spleen with RAT ANTI MOUSE CD4: LOW ENDOTOXIN