|Application / Reactivity||Human||Mouse (Murine)||Rat (Meriones)|
|Western Blotting (WB)||361 Antibodies||162 Antibodies||1 Antibodies|
|Proximity Ligation Assay (PLA)||3 Antibodies||1 Antibodies|
|Intracellular Staining (ICS)||3 Antibodies||3 Antibodies|
|Immunoprecipitation (IP)||38 Antibodies||21 Antibodies|
|Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))||61 Antibodies||29 Antibodies|
|Immunohistochemistry (IHC)||218 Antibodies||117 Antibodies|
|Immunohistochemistry (Frozen Sections) (IHC (fro))||2 Antibodies||1 Antibodies|
|Immunofluorescence (Paraffin-embedded Sections) (IF (p))||39 Antibodies||37 Antibodies|
|Immunofluorescence (IF)||69 Antibodies|
|Antigen||CAMP Responsive Element Binding Protein 1 (CREB1) Antibodies|
|Reactivity||Human, Mouse (Murine), Rat (Meriones) Alternatives|
|Conjugate||This CREB1 antibody is un-conjugated Alternatives|
Western Blotting (WB)
|5 references available|
|Supplier||Log in to see|
Product Details anti-CREB1 AntibodyTarget Details CREB1 Application Details Handling References for anti-CREB1 Antibody (ABIN1944898) Images
|Purification||This antibody is purified through a protein G column, followed by dialysis against PBS.|
|Immunogen||This CREB1 antibody is generated from a mouse immunized with a recombinant protein from human CREB1.|
Target Details CREB1Product Details anti-CREB1 Antibody Application Details Handling References for anti-CREB1 Antibody (ABIN1944898) Images back to top
|Alternative Name||CREB1 (CREB1 Antibody Abstract)|
Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells.
Synonyms: Cyclic AMP-responsive element-binding protein 1, CREB-1, cAMP-responsive element-binding protein 1, CREB1
|Molecular Weight||36688 Da|
|Pathways||TCR Signaling, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway|
Application DetailsProduct Details anti-CREB1 Antibody Target Details CREB1 Handling References for anti-CREB1 Antibody (ABIN1944898) Images back to top
|Application Notes||WB - 1:1000|
|Restrictions||For Research Use only|
HandlingProduct Details anti-CREB1 Antibody Target Details CREB1 Application Details References for anti-CREB1 Antibody (ABIN1944898) Images back to top
|Buffer||Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.|
|Precaution of Use||WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.|
References for anti-CREB1 Antibody (ABIN1944898)Product Details anti-CREB1 Antibody Target Details CREB1 Application Details Handling Images back to top
|Product cited in:||
Hoeffler, Meyer, Yun et al.: "Cyclic AMP-responsive DNA-binding protein: structure based on a cloned placental cDNA." in: Science (New York, N.Y.), Vol. 242, Issue 4884, pp. 1430-3, 1989 (PubMed).
Yoshimura, Fujisawa, Yoshida: "Multiple cDNA clones encoding nuclear proteins that bind to the tax-dependent enhancer of HTLV-1: all contain a leucine zipper structure and basic amino acid domain." in: The EMBO journal, Vol. 9, Issue 8, pp. 2537-42, 1990 (PubMed).
Berkowitz, Gilman: "Two distinct forms of active transcription factor CREB (cAMP response element binding protein)." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 87, Issue 14, pp. 5258-62, 1990 (PubMed).
Waeber, Meyer, Hoeffler et al.: "Diversification of cyclic AMP-responsive enhancer binding proteins-generated by alternative exon splicing." in: Transactions of the Association of American Physicians, Vol. 103, pp. 28-37, 1992 (PubMed).
Short, Manohar, Furtado et al.: "Nucleotide and derived amino-acid sequences of the CRE-binding proteins from rat C6 glioma and HeLa cells." in: Nucleic acids research, Vol. 19, Issue 15, pp. 4290, 1991 (PubMed).
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