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anti-Human ICOS antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended ICOS Antibody (supplied by: Log in to see )

Antigen
Inducible T-Cell Co-Stimulator (ICOS) Antibodies
  • AILIM
  • Ailim
  • CCLP
  • CD278
  • CRP-1
  • CVID1
  • H4
  • ICOS
  • Ly115
Epitope
C-Term
6
3
2
2
2
1
1
Reactivity
Human
60
57
42
1
Host
Rabbit
33
25
13
10
2
1
Clonality
Polyclonal
Conjugate
This ICOS antibody is un-conjugated
10
8
7
5
4
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
44
15
13
11
10
7
5
4
4
4
3
3
2
2
2
1
1
1
Supplier
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Catalog No. ABIN783114
$ 599.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008985059 ABIN358624 EIA IHC (p) WB Rabbit Ig C-Term Log in to see Polyclonal 5
0.0008985059 ABIN492678 IHC (p) Rabbit IgG C-Term Log in to see SP98
0.0008985059 ABIN303433 EIA IHC (p) Rabbit AA 171-186 Log in to see Polyclonal
0.0008985059 ABIN1687510 IHC (p) Rabbit IgG C-Term Log in to see SP98
0.0008985059 ABIN1687503 IHC (p) Rabbit IgG C-Term Log in to see SP98
0.0008985059 ABIN1688121 IHC (p) Rabbit IgG C-Term Log in to see Polyclonal
0.0008985059 ABIN742380 IF (p) IHC (p) WB Rabbit IgG Log in to see Polyclonal
0.0008985059 ABIN1687498 IHC (p) Rabbit IgG C-Term Log in to see Polyclonal
0.0008985059 ABIN1173553 ICC IHC (fro) IHC (p) ELISA WB Rabbit IgG AA 31-190 Log in to see Polyclonal
0.0008985059 ABIN742382 IHC (p) WB Biotin Rabbit IgG Log in to see Polyclonal
0.0008985059 ABIN742389 IHC (p) WB HRP Rabbit IgG Log in to see Polyclonal

Similar anti-ICOS Antibodies

Application / Reactivity Human
Activation (Act) 2 Antibodies
Blocking Reagent (BR) 2 Antibodies
ELISA 2 Antibodies
Enzyme Immunoassay (EIA) 2 Antibodies
Flow Cytometry (FACS) 32 Antibodies
Immunocytochemistry (ICC) 1 Antibodies
Immunofluorescence (IF) 2 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies
Immunohistochemistry (IHC) 5 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 2 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 12 Antibodies
Immunoprecipitation (IP) 3 Antibodies
Intracellular Flow Cytometry (ICFC) 4 Antibodies
Western Blotting (WB) 10 Antibodies

General

Antigen Inducible T-Cell Co-Stimulator (ICOS) Antibodies
Epitope C-Term
(6), (3), (2), (2), (2), (1), (1)
Reactivity Human
(60), (57), (42), (1)
Host Rabbit
(33), (25), (13), (10), (2), (1)
Clonality
Polyclonal
Conjugate This ICOS antibody is un-conjugated
(10), (8), (7), (5), (4), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(44), (15), (13), (11), (10), (7), (5), (4), (4), (4), (3), (3), (2), (2), (2), (1), (1), (1)
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Product Details anti-ICOS Antibody

Target Details ICOS Application Details Handling Images
Specificity Recognizes CD278/ICOS.
Cellular Localization: Membrane.
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Immunoaffinity Chromatography
Immunogen A synthetic peptide derived from near C-terminus of Human CD278 protein.
Isotype IgG

Target Details ICOS

Product Details anti-ICOS Antibody Application Details Handling Images back to top
Antigen
Alternative Name CD278 / ICOS (ICOS Antibody Abstract)
Background CD278 belongs to the CD28 and CTLA-4 cell-surface receptor family. It forms homodimers and plays an important role in cell-cell signaling, immune responses, and regulation of cell proliferation. It enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. It is essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. It does not up-regulate the production of interleukin-2, but superinduces the synthesis of interleukin-10. CD278 prevents the apoptosis of pre-activated T-cells and it plays a critical role in CD40-mediated class switching of immunoglobin isotypes (by similarity).Synonyms: AILIM, Activation-inducible lymphocyte immunomediatory molecule, Inducible T-cell costimulator
Molecular Weight 23 kDa
Gene ID 29851
NCBI Accession NP_036224
UniProt Q9Y6W8
Research Area Immunology, Inflammation
Pathways TCR Signaling

Application Details

Product Details anti-ICOS Antibody Target Details ICOS Handling Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-ICOS Antibody Target Details ICOS Application Details Images back to top
Format Liquid
Buffer PBS, pH 7.6 with 1 % BSA and 0.09 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store the antibody undiluted at 2-8 °C. DO NOT FREEZE!

Images

Product Details anti-ICOS Antibody Target Details ICOS Application Details Handling back to top
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-ICOS antibody (Inducible T-Cell Co-Stimulator) (C-Term) (ABIN783114) AP23811PU CD278 antibody staining of Human Tonsil.