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anti-Human ICOS antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended ICOS Antibody (supplied by: Log in to see )

Antigen
Inducible T-Cell Co-Stimulator (ICOS) Antibodies
  • ICOS
  • AILIM
  • CCLP
  • CRP-1
  • H4
  • Ly115
  • CD278
  • CVID1
  • Ailim
  • inducible T-cell co-stimulator
  • inducible T cell co-stimulator
  • ICOS
  • LOC100232284
  • Icos
Epitope
C-Term
6
3
3
2
2
2
1
Reactivity
Human
54
54
42
1
Host
Rabbit
35
25
8
5
Clonality
Polyclonal
Conjugate
This ICOS antibody is un-conjugated
9
8
4
3
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
31
15
13
13
10
7
4
4
4
3
3
2
2
2
2
1
1
1
Supplier
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Catalog No. ABIN783114
$ 610.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN358624 EIA IHC (p) WB Rabbit Ig C-Term Log in to see Polyclonal 5
1 ABIN492678 IHC (p) Rabbit IgG C-Term Log in to see SP98
1 ABIN303433 EIA IHC (p) Rabbit AA 171-186 Log in to see Polyclonal
1 ABIN1687510 IHC (p) Rabbit IgG C-Term Log in to see SP98
1 ABIN1687503 IHC (p) Rabbit IgG C-Term Log in to see SP98
1 ABIN1688121 IHC (p) Rabbit IgG C-Term Log in to see Polyclonal
1 ABIN742380 IF (p) IHC (p) WB Rabbit IgG Log in to see Polyclonal
1 ABIN1687498 IHC (p) Rabbit IgG C-Term Log in to see Polyclonal
1 ABIN742389 IHC (p) WB HRP Rabbit IgG Log in to see Polyclonal
1 ABIN742382 IHC (p) WB Biotin Rabbit IgG Log in to see Polyclonal

Top referenced anti-ICOS antibody for Immunohistochemistry (Paraffin-embedded Sections)

Similar anti-ICOS Antibodies

Application / Reactivity Human
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Blocking Reagent (BR) 2 Antibodies
ELISA 1 Antibodies
Enzyme Immunoassay (EIA) 2 Antibodies
Flow Cytometry (FACS) 24 Antibodies
Immunocytochemistry (ICC) 1 Antibodies
Immunofluorescence (IF) 2 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 13 Antibodies
Immunohistochemistry (IHC) 6 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 1 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 11 Antibodies
Immunoprecipitation (IP) 4 Antibodies
Intracellular Flow Cytometry (ICFC) 4 Antibodies
Western Blotting (WB) 10 Antibodies

General

Antigen Inducible T-Cell Co-Stimulator (ICOS) Antibodies
Epitope C-Term
(6), (3), (3), (2), (2), (2), (1)
Reactivity Human
(54), (54), (42), (1)
Host Rabbit
(35), (25), (8), (5)
Clonality
Polyclonal
Conjugate This ICOS antibody is un-conjugated
(9), (8), (4), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(31), (15), (13), (13), (10), (7), (4), (4), (4), (3), (3), (2), (2), (2), (2), (1), (1), (1)
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Product Details anti-ICOS Antibody

Target Details ICOS Application Details Handling Images
Specificity Recognizes CD278/ICOS.
Cellular Localization: Membrane.
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Immunoaffinity Chromatography
Immunogen A synthetic peptide derived from near C-terminus of Human CD278 protein.
Isotype IgG

Target Details ICOS

Product Details anti-ICOS Antibody Application Details Handling Images back to top
Antigen
Alternative Name CD278 / ICOS (ICOS Antibody Abstract)
Background CD278 belongs to the CD28 and CTLA-4 cell-surface receptor family. It forms homodimers and plays an important role in cell-cell signaling, immune responses, and regulation of cell proliferation. It enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. It is essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. It does not up-regulate the production of interleukin-2, but superinduces the synthesis of interleukin-10. CD278 prevents the apoptosis of pre-activated T-cells and it plays a critical role in CD40-mediated class switching of immunoglobin isotypes (by similarity).Synonyms: AILIM, Activation-inducible lymphocyte immunomediatory molecule, Inducible T-cell costimulator
Molecular Weight 23 kDa
Gene ID 29851
NCBI Accession NP_036224
UniProt Q9Y6W8
Research Area Immunology, Inflammation
Pathways TCR Signaling

Application Details

Product Details anti-ICOS Antibody Target Details ICOS Handling Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-ICOS Antibody Target Details ICOS Application Details Images back to top
Format Liquid
Buffer PBS, pH 7.6 with 1 % BSA and 0.09 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store the antibody undiluted at 2-8 °C. DO NOT FREEZE!

Images

Product Details anti-ICOS Antibody Target Details ICOS Application Details Handling back to top
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-ICOS antibody (Inducible T-Cell Co-Stimulator) (C-Term) (ABIN783114) AP23811PU CD278 antibody staining of Human Tonsil.