anti-Human LAT antibody for Enzyme Immunoassay

Recommended LAT Antibody (supplied by: Log in to see )

Antigen
Linker For Activation of T Cells (LAT) Antibodies
  • LAT
  • lat
  • LAT1
  • pp36
  • linker for activation of T cells
  • LAT
  • lat
  • Lat
Epitope
C-Term
30
24
20
19
18
12
8
8
4
4
4
4
4
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
278
118
103
3
2
1
Host
Goat
148
140
11
2
Clonality
Polyclonal
Conjugate
This LAT antibody is un-conjugated
12
12
10
8
8
7
7
7
6
6
6
5
4
4
4
4
4
3
3
3
3
3
3
3
2
2
2
1
1
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
210
68
66
50
41
39
22
21
14
6
3
2
2
1
1
1
1
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Catalog No. ABIN5552980
$ 375.38
Plus shipping costs $45.00

General

Antigen Linker For Activation of T Cells (LAT) Antibodies
Epitope C-Term
(30), (24), (20), (19), (18), (12), (8), (8), (4), (4), (4), (4), (4), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(278), (118), (103), (3), (2), (1)
Host Goat
(148), (140), (11), (2)
Clonality
Polyclonal
Conjugate This LAT antibody is un-conjugated
(12), (12), (10), (8), (8), (7), (7), (7), (6), (6), (6), (5), (4), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (1), (1)
Application Enzyme Immunoassay (EIA), Western Blotting (WB)
(210), (68), (66), (50), (41), (39), (22), (21), (14), (6), (3), (2), (2), (1), (1), (1), (1)
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Product Details anti-LAT Antibody

Target Details LAT Application Details Handling Images
Sequence C-GAPDYENLQE LN
Specificity This antibody is expected to recognize isoform a (NP_055202.1), isoform b (NP_001014987.1 and NP_001014989.1) and isoform c (NP_001014988.1).
Cross-Reactivity (Details) Species reactivity (tested):Human, Mouse and Rat.
Purification Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide.
Immunogen Peptide from the C Terminus of the protein sequence according to NP_055202.1, NP_001014987.1, NP_001014989.1, NP_001014988.1

Target Details LAT

Product Details anti-LAT Antibody Application Details Handling Images back to top
Antigen
Alternative Name LAT (LAT Antibody Abstract)
Background Linker for activation of T cells (LAT) is an integral membrane protein (36 to 38 kD), which plays an important role in linking engagement of the TCR to the biochemical events of T cell activation. LAT antibody stains thymus and peripheral lymphoid tissues such as T cell areas in lymph nodes and spleen. LAT is expressed in T lymphocytes in interstitial spaces, platelets and megakaryocytes. LAT is not expressed in B cells, macrophages, plasma cells, monocytes, epithelial histiocytes and dendritic cells.Synonyms: 36 kDa Phospho-Tyrosine Adapter Protein, Linker For Activation of T-Cells Family Member 1, p36-38, pp36
Molecular Weight 27.9kDa (NP_055202.1).
Gene ID 27040
NCBI Accession NP_001014987
UniProt O43561
Research Area Adaptive Immunity, Signaling
Pathways TCR Signaling, Fc-epsilon Receptor Signaling Pathway

Application Details

Product Details anti-LAT Antibody Target Details LAT Handling Images back to top
Application Notes Peptide ELISA: 1/2,000. Western Blot: 1-3 μg/mL. Detects a band of Approx 35 kDa in Human PBMC lysates(Predicted Molecular Weight: 35 kDa).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-LAT Antibody Target Details LAT Application Details Images back to top
Concentration 0.5 mg/mL
Buffer Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Store the antibody (in aliquots) at -20 °C.