anti-Human LAT antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended LAT Antibody (supplied by: Log in to see )

Antigen
Linker For Activation of T Cells (LAT) Antibodies
  • LAT
  • lat
  • LAT1
  • pp36
  • linker for activation of T cells
  • LAT
  • lat
  • Lat
Epitope
pTyr161
29
25
20
19
18
12
8
8
4
4
4
4
4
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
278
118
103
3
2
1
Host
Rabbit
147
140
12
2
Clonality
Polyclonal
Conjugate
This LAT antibody is un-conjugated
12
12
10
8
8
7
7
7
6
6
6
5
4
4
4
4
4
3
3
3
3
3
3
3
2
2
2
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
210
68
66
49
41
38
22
21
14
6
3
2
2
1
1
1
1
1
Options
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Catalog No. ABIN1386362
$ 317.90
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
13.588196 ABIN293627 IHC (p) IP WB Mouse IgG1 Cytoplasmic Domain Log in to see LAT1111
13.588196 ABIN4330393 IHC (p) WB Rabbit Log in to see Polyclonal
13.588196 ABIN4330362 IHC IHC (p) WB Rabbit IgG Log in to see Polyclonal
1 ABIN3043991 ICC IHC (p) WB Rabbit IgG AA 242-262, C-Term Log in to see Polyclonal
1 ABIN614546 IHC (p) IP WB Mouse IgG1 Log in to see LAT-10-17 (10-17)
1 ABIN1406492 IHC (p) WB HRP Rabbit IgG pTyr161 Log in to see Polyclonal
1 ABIN573989 IHC (p) IP WB Mouse IgG1, kappa Log in to see LAT-10-17 (10-17)
1 ABIN599213 IHC (p) ELISA WB Mouse IgG1, kappa AA 1-234 Log in to see 3B11-1D5
1 ABIN1406486 IHC (p) WB HRP Rabbit IgG Log in to see Polyclonal
1 ABIN1406498 IHC (p) WB HRP Rabbit IgG pTyr200 Log in to see Polyclonal
1 ABIN1388599 IHC (p) WB Biotin Rabbit IgG pTyr161 Log in to see Polyclonal
1 ABIN1102812 IHC (p) WB Rabbit AA 70-120 Log in to see Polyclonal
1 ABIN1388605 IHC (p) WB Biotin Rabbit IgG pTyr200 Log in to see Polyclonal
1 ABIN1388593 IHC (p) WB Biotin Rabbit IgG Log in to see Polyclonal
1 ABIN1386363 IF (p) IHC (p) WB Rabbit IgG pTyr200 Log in to see Polyclonal
1 ABIN1387471 IF (p) IHC (p) WB Rabbit IgG Log in to see Polyclonal
1 ABIN1724041 IHC (p) IP WB Mouse IgG1 Log in to see LAT1111
1 ABIN2624774 ICC IHC (p) WB Rabbit IgG AA 242-262 Log in to see Polyclonal
1 ABIN1724096 IHC (p) IP WB Mouse IgG1 kappa Log in to see LAT-10-17 (10-17)
1 ABIN565313 IHC (p) ELISA WB Mouse IgG1 kappa AA 1-233, full length Log in to see 3B11-1D5

General

Antigen Linker For Activation of T Cells (LAT) Antibodies
Epitope pTyr161
(29), (25), (20), (19), (18), (12), (8), (8), (4), (4), (4), (4), (4), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(278), (118), (103), (3), (2), (1)
Host Rabbit
(147), (140), (12), (2)
Clonality
Polyclonal
Conjugate This LAT antibody is un-conjugated
(12), (12), (10), (8), (8), (7), (7), (7), (6), (6), (6), (5), (4), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (1), (1)
Application Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(210), (68), (66), (49), (41), (38), (22), (21), (14), (6), (3), (2), (2), (1), (1), (1), (1), (1)
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Product Details anti-LAT Antibody

Target Details LAT Application Details Handling Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic phosphopeptide derived from human LAT around the phosphorylation site of Tyr161
Isotype IgG

Target Details LAT

Product Details anti-LAT Antibody Application Details Handling Images back to top
Antigen
Alternative Name LAT (LAT Antibody Abstract)
Background

Required for TCR (T-cell antigen receptor)- and pre-TCR-mediated signaling, both in mature T-cells and during their development. Involved in FCGR3 (low affinity immunoglobulin gamma Fc region receptor III)-mediated signaling in natural killer cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Couples activation of these receptors and their associated kinases with distal intracellular events such as mobilization of intracellular calcium stores, PKC activation, MAPK activation or cytoskeletal reorganization through the recruitment of PLCG1, GRB2, GRAP2, and other signaling molecules.

Subcellular location: Cytoplasm

Synonyms: LAT1, pp36, Linker for activation of T-cells family member 1, 36 kDa phospho-tyrosine adapter protein, p36-38, LAT

Gene ID 27040
UniProt O43561
Research Area Signaling, Adaptive Immunity
Pathways TCR Signaling, Fc-epsilon Receptor Signaling Pathway

Application Details

Product Details anti-LAT Antibody Target Details LAT Handling Images back to top
Application Notes WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200
Restrictions For Research Use only

Handling

Product Details anti-LAT Antibody Target Details LAT Application Details Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

Images

Product Details anti-LAT Antibody Target Details LAT Application Details Handling back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-Linker For Activation of T Cells (LAT) (pTyr161) antibody (ABIN1386362) Formalin-fixed and paraffin embedded human lung carcinoma labeled with Anti-Phospho-L...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Linker For Activation of T Cells (LAT) (pTyr161) antibody (ABIN1386362) Paraformaldehyde-fixed, paraffin embedded rat spleen tissue, Antigen retrieval by boi...