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anti-Human RIPK2 antibody for Immunofluorescence

Recommended RIPK2 Antibody (supplied by: Log in to see )

Antigen
Receptor-Interacting Serine-threonine Kinase 2 (RIPK2) Antibodies
  • RIPK2
  • 2210420D18Rik
  • CARD3
  • CARDIAK
  • CCK
  • D4Bwg0615e
  • RICK
  • RIP2
  • GIG30
  • receptor-interacting serine-threonine kinase 2
  • receptor (TNFRSF)-interacting serine-threonine kinase 2
  • RIPK2
  • LOC100223072
  • Ripk2
Epitope
AA 508-522, C-Term
29
16
9
8
7
5
5
5
5
5
3
3
2
2
2
2
2
2
2
2
1
1
1
Reactivity
Human
146
60
34
5
5
4
3
3
2
2
1
Host
Rabbit
127
16
5
Clonality
Polyclonal
Conjugate
This RIPK2 antibody is un-conjugated
6
5
4
2
2
2
Application
Enzyme Immunoassay (EIA), Immunofluorescence (IF), Western Blotting (WB)
137
71
49
25
19
19
6
3
2
2
1
1
Supplier
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Catalog No. ABIN500601
$ 401.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
12.242198 ABIN500599 EIA IF WB Rabbit IgG N-Term Log in to see Polyclonal 2
12.242198 ABIN2792136 IF WB Rabbit Middle Region Log in to see Polyclonal 1
12.242198 ABIN968828 IF WB Mouse IgG1 AA 333-532 Log in to see 25-RIG 4
12.242198 ABIN968829 IF WB Mouse IgG1 AA 333-532 Log in to see 25-RIG 4
12.242198 ABIN3198294 IC IF IHC WB Rabbit Log in to see Polyclonal
12.242198 ABIN1874609 IF IHC WB Rabbit IgG Log in to see Polyclonal
12.242198 ABIN442393 ICC IF IHC (p) IHC WB Rabbit IgG Center Log in to see Polyclonal
12.242198 ABIN4350592 ELISA ICC IF WB Rabbit Log in to see Polyclonal
12.242198 ABIN4350591 ELISA ICC IF IHC IHC (p) WB Rabbit C-Term Log in to see Polyclonal
12.242198 ABIN4350593 ICC IF IHC IHC (p) WB Rabbit IgG Log in to see Polyclonal
12.242198 ABIN4350594 ICC IF IHC IHC (p) WB Rabbit IgG Log in to see Polyclonal
12.242198 ABIN2405362 IF IHC WB Rabbit IgG Log in to see Polyclonal
12.242198 ABIN522204 IF WB Rabbit AA 1-540, full length Log in to see Polyclonal
1 ABIN318972 IHC (fro) IF WB Rabbit IgG N-Term Log in to see Polyclonal
1 ABIN302855 IF IHC (p) WB Rabbit Log in to see Polyclonal
1 ABIN2880293 IF IHC WB Rabbit IgG Log in to see Polyclonal
1 ABIN2887130 IF WB Rabbit Log in to see Polyclonal
1 ABIN2700703 IF IHC WB Rabbit IgG Log in to see Polyclonal
1 ABIN2959905 ICC IF ELISA WB Rabbit N-Term Log in to see Polyclonal

Top referenced anti-RIPK2 antibody for Immunofluorescence

Similar anti-RIPK2 Antibodies

Application / Reactivity Human
ELISA 71 Antibodies
Enzyme Immunoassay (EIA) 3 Antibodies
Immunochromatography (IC) 2 Antibodies
Immunocytochemistry (ICC) 23 Antibodies
Immunofluorescence (IF) 20 Antibodies
Immunofluorescence (fixed cells) (IF/ICC) 1 Antibodies
Immunohistochemistry (IHC) 47 Antibodies
Immunohistochemistry (Acetone-fixed) (IHC (af)) 1 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 3 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 19 Antibodies
Immunoprecipitation (IP) 4 Antibodies
Western Blotting (WB) 136 Antibodies

General

Antigen Receptor-Interacting Serine-threonine Kinase 2 (RIPK2) Antibodies
Epitope AA 508-522, C-Term
(29), (16), (9), (8), (7), (5), (5), (5), (5), (5), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1)
Reactivity Human
(146), (60), (34), (5), (5), (4), (3), (3), (2), (2), (1)
Host Rabbit
(127), (16), (5)
Clonality
Polyclonal
Conjugate This RIPK2 antibody is un-conjugated
(6), (5), (4), (2), (2), (2)
Application Enzyme Immunoassay (EIA), Immunofluorescence (IF), Western Blotting (WB)
(137), (71), (49), (25), (19), (19), (6), (3), (2), (2), (1), (1)
Pubmed 3 references available
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Product Details anti-RIPK2 Antibody

Target Details RIPK2 Application Details Handling References for anti-RIPK2 Antibody (ABIN500601) Images
Specificity This antibody detects RICK at C-term.
Cross-Reactivity (Details) Species reactivity (tested):Human
Purification Peptide affinity chromatography
Immunogen RICK antibody was raised against a peptide corresponding to amino acids 508 to 522 of human origin.
Isotype IgG

Target Details RIPK2

Product Details anti-RIPK2 Antibody Application Details Handling References for anti-RIPK2 Antibody (ABIN500601) Images back to top
Antigen
Alternative Name RIPK2 (RIPK2 Antibody Abstract)
Background Apoptosis is mediated by death domain (DD) and/or caspase recruitment domain (CARD) containing molecules and a caspase family of proteases. DD-containing serine/threonine kinase RIP regulates Fas-induced apoptosis. A novel CARD-containing serine/threonine kinase was recently identified and designated RICK/RIP2/CARDIAK for RIP-like interacting CLARP kinase, receptor interacting protein-2, and CARD-containing ICE associated kinase, respectively, (1-3). RICK contains an N-terminal kinase catalytic domain and a C-terminal CARD domain. Overexpression of RICK induced apoptosis and activation of NF-kappaB and JNK. RICK interacts with members of the TRAF family, CLARP and caspase-1. Thus, RICK represents a novel kinase that regulates TNF and Fas induced-apoptosis and that is involved in the generation of proinflammatory cytokine IL-1b. The messenger RNA of RICK is expressed in multiple human tissues (1).Synonyms: CARD-containing IL-1 beta ICE-kinase, CARDIAK, RICK, RIP-2, RIP-like-interacting CLARP kinase, RIP2, Receptor-interacting protein 2, Receptor-interacting serine/threonine-protein kinase 2
Gene ID 8767
UniProt O43353
Research Area Apoptosis/Necrosis, Signaling
Pathways TCR Signaling, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin

Application Details

Product Details anti-RIPK2 Antibody Target Details RIPK2 Handling References for anti-RIPK2 Antibody (ABIN500601) Images back to top
Application Notes ELISA. Western blot: 1: 500, an approximately 60 kDa band can be detected. Immunoflourescence.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-RIPK2 Antibody Target Details RIPK2 Application Details References for anti-RIPK2 Antibody (ABIN500601) Images back to top
Buffer PBS containing 0.02 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

References for anti-RIPK2 Antibody (ABIN500601)

Product Details anti-RIPK2 Antibody Target Details RIPK2 Application Details Handling Images back to top
Background publications

Inohara, del Peso, Koseki, Chen, Núñez: "RICK, a novel protein kinase containing a caspase recruitment domain, interacts with CLARP and regulates CD95-mediated apoptosis." in: The Journal of biological chemistry, Vol. 273, Issue 20, pp. 12296-300, 1998

McCarthy, Ni, Dixit: "RIP2 is a novel NF-kappaB-activating and cell death-inducing kinase." in: The Journal of biological chemistry, Vol. 273, Issue 27, pp. 16968-75, 1998

Thome, Hofmann, Burns, Martinon, Bodmer, Mattmann, Tschopp: "Identification of CARDIAK, a RIP-like kinase that associates with caspase-1." in: Current biology : CB, Vol. 8, Issue 15, pp. 885-8, 1998

Images

Product Details anti-RIPK2 Antibody Target Details RIPK2 Application Details Handling References for anti-RIPK2 Antibody (ABIN500601) back to top
Supplier Images
Immunofluorescence (IF) image for anti-RIPK2 antibody (Receptor-Interacting Serine-threonine Kinase 2) (AA 508-522) (ABIN500601) Immunocytochemistry of RICK in K562 cells with this product at 5 μg/ml.