anti-Rat (Rattus) RIPK2 antibody for ELISA

Recommended RIPK2 Antibody (supplied by: Log in to see )

Antigen
Receptor-Interacting Serine-threonine Kinase 2 (RIPK2) Antibodies
  • RIPK2
  • 2210420D18Rik
  • CARD3
  • CARDIAK
  • CCK
  • D4Bwg0615e
  • RICK
  • RIP2
  • GIG30
  • receptor-interacting serine-threonine kinase 2
  • receptor (TNFRSF)-interacting serine-threonine kinase 2
  • RIPK2
  • LOC100223072
  • Ripk2
Epitope
N-Term
28
12
9
8
7
5
5
5
5
5
3
3
3
2
2
2
2
2
2
2
2
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
144
55
32
6
5
5
4
4
3
2
1
Host
Rabbit
125
16
5
Clonality
Polyclonal
Conjugate
This RIPK2 antibody is un-conjugated
6
6
4
2
2
2
Application
Immunocytochemistry (ICC), ELISA, Western Blotting (WB)
134
69
47
22
21
20
7
3
3
2
1
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Catalog No. ABIN1003093
$ 466.62
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN599061 ELISA WB Mouse IgG2a, kappa AA 431-541 Log in to see 6F7
1 ABIN599062 ELISA WB Mouse IgG2a, kappa AA 431-541 Log in to see 3D9
1 ABIN331273 IP ELISA WB Mouse IgG1, kappa Log in to see
1 ABIN1031540 ICC ELISA WB Rabbit N-Term Log in to see Polyclonal
1 ABIN4350592 ELISA ICC IF WB Rabbit Log in to see Polyclonal
1 ABIN1091412 ELISA WB Rabbit IgG Log in to see Polyclonal
1 ABIN1091413 ELISA WB Rabbit IgG Log in to see Polyclonal
1 ABIN1888198 ICC ELISA WB Rabbit N-Term Log in to see Polyclonal
1 ABIN2959906 ICC ELISA WB Rabbit N-Term Log in to see Polyclonal
1 ABIN1585140 ICC ELISA WB Rabbit Log in to see Polyclonal

General

Antigen Receptor-Interacting Serine-threonine Kinase 2 (RIPK2) Antibodies
Epitope N-Term
(28), (12), (9), (8), (7), (5), (5), (5), (5), (5), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(144), (55), (32), (6), (5), (5), (4), (4), (3), (2), (1)
Host Rabbit
(125), (16), (5)
Clonality
Polyclonal
Conjugate This RIPK2 antibody is un-conjugated
(6), (6), (4), (2), (2), (2)
Application Immunocytochemistry (ICC), ELISA, Western Blotting (WB)
(134), (69), (47), (22), (21), (20), (7), (3), (3), (2), (1)
Pubmed 3 references available
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Product Details anti-RIPK2 Antibody

Target Details RIPK2 Application Details Handling References for anti-RIPK2 antibody (ABIN1003093) Images
Blocking Peptide Blocking peptide for this product available: ABIN1004183
Purification Affinity chromatography purified via peptide column.
Immunogen Rabbit polyclol RICK antibody was raised against a peptide corresponding to amino acids near the amino terminus of human RICK (Genbank accession no. O43353).
Isotype IgG

Target Details RIPK2

Product Details anti-RIPK2 Antibody Application Details Handling References for anti-RIPK2 antibody (ABIN1003093) Images back to top
Antigen
Alternative Name RIP-Like Interacting CLARP Kinase (RIPK2 Antibody Abstract)
Background Apoptosis is mediated by death domain (DD) and/or caspase recruitment domain (CARD) containing molecules and a caspase family of proteases. DD-containing serine/threonine kinase RIP regulates Fas-induced apoptosis. A novel CARD-containing serine/threonine kinase was recently identified and designated RICK/RIP2/CARDIAK for RIP-like interacting CLARP kinase, receptor interacting protein-2, and CARD-containing ICE associated kinase, respectively. RICK contains an N-terminal kinase catalytic domain and a C-terminal CARD domain. Overexpression of RICK induced apoptosis and activation of NF-kappaB and JNK. RICK interacts with members of the TRAF family, CLARP and caspase-1. Thus, RICK represents a novel kinase that regulates TNF and Fas induced-apoptosis and that is involved in the generation of proinflammatory cytokine IL-1beta. The messenger RNA of RICK is expressed in multiple human tissues.
Pathways TCR Signaling, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Toll-Like Receptors Cascades

Application Details

Product Details anti-RIPK2 Antibody Target Details RIPK2 Handling References for anti-RIPK2 antibody (ABIN1003093) Images back to top
Application Notes RICK antibody can be used for detection of RICK by Western blot at 0.5 - 1 µg/ml. (Optimal dilution should be determined by user.) A431 or K562 whole cell lysate can be used as positive control and an approximately 60 kDa band can be detected. Antibody can also be used for immunocytochemistry and ELISA and might be suited for other applications not tested so far. RICK antibody is human, mouse, and rat reactive.
Restrictions For Research Use only

Handling

Product Details anti-RIPK2 Antibody Target Details RIPK2 Application Details References for anti-RIPK2 antibody (ABIN1003093) Images back to top
Format Liquid
Buffer Antibody is supplied in PBS containing 0.02% sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Antibody can be stored at 4 °C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. During shipment, small volumes of antibody will occasionally become entrapped in the seal of the product vial. For products with volumes of 200 myl or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap.
Storage 4 °C
Expiry Date 12 months

References for anti-RIPK2 antibody (ABIN1003093)

Product Details anti-RIPK2 Antibody Target Details RIPK2 Application Details Handling Images back to top
Background publications

Inohara, del Peso, Koseki, Chen, Núñez: "RICK, a novel protein kinase containing a caspase recruitment domain, interacts with CLARP and regulates CD95-mediated apoptosis." in: The Journal of biological chemistry, Vol. 273, Issue 20, pp. 12296-300, 1998

McCarthy, Ni, Dixit: "RIP2 is a novel NF-kappaB-activating and cell death-inducing kinase." in: The Journal of biological chemistry, Vol. 273, Issue 27, pp. 16968-75, 1998

Thome, Hofmann, Burns, Martinon, Bodmer, Mattmann, Tschopp: "Identification of CARDIAK, a RIP-like kinase that associates with caspase-1." in: Current biology : CB, Vol. 8, Issue 15, pp. 885-8, 1998