anti-Human VAV1 antibody for ELISA

Recommended VAV1 Antibody (supplied by: Log in to see )

Antigen
Vav 1 Oncogene (VAV1) Antibodies
  • VAV
  • Vav
  • vav-T
  • vav 1 guanine nucleotide exchange factor
  • vav 1 oncogene
  • VAV1
  • Vav1
  • vav1
Epitope
AA 121-324
37
25
23
20
15
10
9
8
6
4
3
3
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
Reactivity
Human
184
76
73
4
4
2
2
2
2
1
Host
Mouse
135
50
Clonality
Monoclonal
Conjugate
This VAV1 antibody is un-conjugated
5
5
4
3
3
3
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), ELISA, Western Blotting (WB)
157
70
26
22
14
14
11
6
3
1
1
1
1
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Catalog No. ABIN969581
$ 430.10
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
10.750587 ABIN521297 ELISA WB Mouse IgG2a kappa AA 681-790, partial Log in to see 1A6
10.750587 ABIN521298 ELISA WB Mouse IgG2a kappa AA 681-790, partial Log in to see 2C11
10.750587 ABIN521299 IF ELISA WB Mouse IgG2a kappa AA 681-790, partial Log in to see 3A11
10.750587 ABIN1845807 FACS ELISA WB Mouse IgG1 AA 121-324 Log in to see
1 ABIN1532426 IF ELISA Rabbit IgG AA 131-180 Log in to see Polyclonal 1
1 ABIN1533035 ELISA WB Rabbit IgG AA 141-190 Log in to see Polyclonal
1 ABIN1531997 ELISA WB Rabbit IgG AA 141-190, pTyr174 Log in to see Polyclonal
1 ABIN3187609 ELISA WB Rabbit IgG Tyr292 Log in to see Polyclonal
1 ABIN3187457 ELISA WB Rabbit IgG Tyr292 Log in to see Polyclonal
1 ABIN1490879 FACS ELISA WB Mouse IgG1 AA 121-324 Log in to see 2E11
1 ABIN4364878 CyTOF ELISA FACS WB Mouse IgG1 Log in to see 2E11
1 ABIN1450278 IHC ELISA Rabbit IgG AA 131-180, pTyr160 Log in to see Polyclonal
1 ABIN2888554 ELISA WB Rabbit IgG pTyr174 Log in to see Polyclonal
1 ABIN2888713 IF ELISA Rabbit IgG AA 131-180 Log in to see Polyclonal
1 ABIN2889078 ELISA WB Rabbit IgG AA 141-190 Log in to see Polyclonal
1 ABIN4881134 ELISA FACS WB Mouse IgG1 AA 121-324 Log in to see 2E11
1 ABIN3182173 ELISA WB Rabbit IgG pTyr174 Log in to see Polyclonal
1 ABIN3182845 ELISA IHC Rabbit IgG pTyr160 Log in to see Polyclonal
1 ABIN3182172 ELISA IHC WB Rabbit IgG pTyr174 Log in to see Polyclonal
1 ABIN3187456 ELISA IHC WB Rabbit IgG Tyr291 Log in to see Polyclonal

General

Antigen Vav 1 Oncogene (VAV1) Antibodies
Epitope AA 121-324
(37), (25), (23), (20), (15), (10), (9), (8), (6), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(184), (76), (73), (4), (4), (2), (2), (2), (2), (1)
Host Mouse
(135), (50)
Clonality (Clone)
Monoclonal   ( )
Conjugate This VAV1 antibody is un-conjugated
(5), (5), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Flow Cytometry (FACS), ELISA, Western Blotting (WB)
(157), (70), (26), (22), (14), (14), (11), (6), (3), (1), (1), (1), (1)
Pubmed 2 references available
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Product Details anti-VAV1 Antibody

Target Details VAV1 Application Details Handling References for anti-VAV1 antibody (ABIN969581) Images
Purification Purified
Immunogen Purified recombinant fragment of human VAV1 (AA 121-324) expressed in E. Coli.
Clone 2-00E-11
Isotype IgG1

Target Details VAV1

Product Details anti-VAV1 Antibody Application Details Handling References for anti-VAV1 antibody (ABIN969581) Images back to top
Antigen
Alternative Name VAV1 (VAV1 Antibody Abstract)
Background The protein encoded by this proto-oncogene is a member of the Dbl family of guanine nucleotide exchange factors (GEF) for the Rho family of GTP binding proteins. The protein is important in hematopoiesis, playing a role in T-cell and B-cell development and activation. This particular GEF has been identified as the specific binding partner of Nef proteins from HIV-1. Coexpression and binding of these partners initiates profound morphological changes, cytoskeletal rearrangements and the JNK/SAPK signaling cascade, leading to increased levels of viral transcription and replication.
Molecular Weight 98.3 kDa
Gene ID 7409
HGNC 7409
Research Area Cancer, Transcription Factors
Pathways TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, CXCR4-mediated Signaling Events

Application Details

Product Details anti-VAV1 Antibody Target Details VAV1 Handling References for anti-VAV1 antibody (ABIN969581) Images back to top
Application Notes ELISA: 1:10000, WB: 1:250, FCM: 1:200 - 1:400
Restrictions For Research Use only

Handling

Product Details anti-VAV1 Antibody Target Details VAV1 Application Details References for anti-VAV1 antibody (ABIN969581) Images back to top
Format Liquid
Buffer PBS with 0.05 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment 4°C, -20°C for long term storage

References for anti-VAV1 antibody (ABIN969581)

Product Details anti-VAV1 Antibody Target Details VAV1 Application Details Handling Images back to top
Product cited in:

Bertagnolo, Nika, Brugnoli, Bonora, Grassilli, Pinton, Capitani: "Vav1 is a crucial molecule in monocytic/macrophagic differentiation of myeloid leukemia-derived cells." in: Cell and tissue research, Vol. 345, Issue 1, pp. 163-75, 2011

Yin, Wan, Li, Du, Zhang, Zhou, Cao: "The distinct role of guanine nucleotide exchange factor Vav1 in Bcl-2 transcription and apoptosis inhibition in Jurkat leukemia T cells." in: Acta pharmacologica Sinica, Vol. 32, Issue 1, pp. 99-107, 2011

Images

Product Details anti-VAV1 Antibody Target Details VAV1 Application Details Handling References for anti-VAV1 antibody (ABIN969581) back to top
Supplier Images
ELISA image for anti-Vav 1 Oncogene (VAV1) (AA 121-324) antibody (ABIN969581) Figure 1: Red: Control Antigen (100 ng), Purple: Antigen (10ng), Green: Antigen (50 n...
Flow Cytometry (FACS) image for anti-Vav 1 Oncogene (VAV1) (AA 121-324) antibody (ABIN969581) Figure 2: Flow cytometric analysis of HeLa cells using VAV1 mouse mAb (green) and neg...
Western Blotting (WB) image for anti-Vav 1 Oncogene (VAV1) (AA 121-324) antibody (ABIN969581) Figure 3: Western blot analysis using VAV1 mouse mAb against Jurkat (1) cell lysate.
Western Blotting (WB) image for anti-Vav 1 Oncogene (VAV1) (AA 121-324) antibody (ABIN969581) Figure 4: Western blot analysis using VAV1 mAb against human VAV1 recombinant protein...
Western Blotting (WB) image for anti-Vav 1 Oncogene (VAV1) (AA 121-324) antibody (ABIN969581) Figure 5: Western blot analysis using VAV1 mAb against HEK293 (1) and VAV1 (AA: 121-3...