You are viewing an incomplete version of our website. Please click to reload the website as full version.

Browse our anti-Polymerase (DNA Directed), delta 1, Catalytic Subunit 125kDa (POLD1) Antibodies

Full name:
anti-Polymerase (DNA Directed), delta 1, Catalytic Subunit 125kDa Antibodies (POLD1)
On www.antibodies-online.com are 44 Polymerase (DNA Directed), delta 1, Catalytic Subunit 125kDa (POLD1) Antibodies from 15 different suppliers available. Additionally we are shipping Polymerase (DNA Directed), delta 1, Catalytic Subunit 125kDa Proteins (3) and Polymerase (DNA Directed), delta 1, Catalytic Subunit 125kDa Kits (1) and many more products for this protein. A total of 50 Polymerase (DNA Directed), delta 1, Catalytic Subunit 125kDa products are currently listed.
Synonyms:
125kDa, 5949, CAA61369, CDC2, CG5949, CRCS10, Dmel\\CG5949, Dm Poldelta, dnapol delta, DNA Pol Delta, l(3)72Ac, POLD, POLD3, Poldelta, Pol delta
list all antibodies Gene Name GeneID UniProt
POLD1 5424 P28340
POLD1 18971 P52431
POLD1 59294 O54747

Show all species

Show all synonyms

Most Popular Reactivities for anti-Polymerase (DNA Directed), delta 1, Catalytic Subunit 125kDa (POLD1) Antibodies

Select your species and application

anti-Human Antibodies:

anti-Mouse (Murine) Antibodies:

anti-Rat (Rattus) Antibodies:

All available anti-Polymerase (DNA Directed), delta 1, Catalytic Subunit 125kDa Antibodies

Go to our pre-filtered search.

Top referenced anti-Polymerase (DNA Directed), delta 1, Catalytic Subunit 125kDa Antibodies

  1. Human Monoclonal POLD1 Primary Antibody for WB - ABIN2853582 : Bermudez, MacNeill, Tappin, Hurwitz: The influence of the Cdc27 subunit on the properties of the Schizosaccharomyces pombe DNA polymerase delta. in The Journal of biological chemistry 2002 (PubMed)
    Show all 3 references for ABIN2853582

More Antibodies against Polymerase (DNA Directed), delta 1, Catalytic Subunit 125kDa Interaction Partners

Fruit Fly (Drosophila melanogaster) Polymerase (DNA Directed), delta 1, Catalytic Subunit 125kDa (POLD1) interaction partners

  1. in Drosophila the alternative TRF1/BRF complex appears responsible for the initiation of all known classes of Pol III transcription

Human Polymerase (DNA Directed), delta 1, Catalytic Subunit 125kDa (POLD1) interaction partners

  1. Mutations in POLE and POLD1 in south east Asia women with grade 3 endometrioid endometrial carcinomas are associated with improved recurrence free survival.

  2. POLD1 germline mutations can result in a variably expressed and probably underdiagnosed segmental progeroid syndrome.

  3. None of the 1188 patients carried the POLD1 p.(Ser478Asn) variant. POLE germline variant carriers are also associated with a microsatellite instable colorectal cancer

  4. POLD1 plays important role in the regulation of cell cycle progression and DNA damage repair

  5. analysis of phenotype of variants of the essential replicative polymerase-delta carrying missense mutations in its active site

  6. POLE and POLD1 mutations explain a fraction of familial CRC (show CALR Antibodies) and polyposis. Sequencing the proofreading domains of POLE and POLD1 should be considered in routine genetic diagnostics.

  7. Germline mutations in the proofreading domains of 2 DNA polymerases (POLE and POLD1) have been associated with a dominantly inherited, highly penetrant syndrome of oligo adenomatous polyposis and early-age-of-diagnosis colorectal and endometrial cancer.

  8. POLE and POLD1 mutations are associated with endometrial cancer.

  9. a single-codon deletion in POLD1 affecting the polymerase active site causes a markedly different phenotype that includes lipodystrophy.

  10. Germline and somatic polymerase epsilon and delta mutations define a new class of hypermutated colorectal and endometrial cancers.

Mouse (Murine) Polymerase (DNA Directed), delta 1, Catalytic Subunit 125kDa (POLD1) interaction partners

  1. reducing expression of individual PRMT7 (show PRMT7 Antibodies) target DNA repair genes showed that only the catalytic subunit of DNA polymerase (show POLB Antibodies), POLD1, was able to resensitize PRMT7 (show PRMT7 Antibodies) knock-down cells to DNA-damaging agents.

  2. A point mutation (D400A) in the proofreading domain of DNA polymerase delta, encoded by the Pold1 gene, inactivates the 3' --> 5' exonuclease (show EXOSC10 Antibodies) of poldelta and causes a mutator and epithelial cancer phenotype in a recessive manner.

  3. Heterozygous mutation at L604 in the polymerase active site of DNA polymerase delta reduces life span, increases genomic instability, and accelerates tumorigenesis in an allele-specific manner, novel findings that have implications for human cancer.

  4. DNA polymerase delta is essential for mammalian early embryogenesis, and the 3'-5' exonuclease (show EXOSC10 Antibodies) activity of DNA polymerase delta is dispensable for normal development but necessary to suppress tumorigenesis

Polymerase (DNA Directed), delta 1, Catalytic Subunit 125kDa (POLD1) Antigen Profile

Antigen Summary

This gene encodes the 125-kDa catalytic subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 6.

Alternative names and synonyms associated with Polymerase (DNA Directed), delta 1, Catalytic Subunit 125kDa (POLD1)

  • DNA-polymerase-delta (DNApol-delta) antibody
  • DNA polymerase delta (POLD1) antibody
  • polymerase (DNA-directed), delta 3, accessory subunit (POLD3) antibody
  • polymerase (DNA-directed), delta 3, accessory subunit (pold3) antibody
  • polymerase (DNA directed), delta 1, catalytic subunit (POLD1) antibody
  • polymerase (DNA directed), delta 1, catalytic subunit (pold1) antibody
  • polymerase (DNA directed), delta 1, catalytic subunit 125kDa (POLD1) antibody
  • polymerase (DNA directed), delta 1, catalytic subunit (Pold1) antibody
  • 125kDa antibody
  • 5949 antibody
  • CAA61369 antibody
  • CDC2 antibody
  • CG5949 antibody
  • CRCS10 antibody
  • Dmel\\CG5949 antibody
  • Dm Poldelta antibody
  • dnapol delta antibody
  • DNA Pol Delta antibody
  • l(3)72Ac antibody
  • POLD antibody
  • POLD3 antibody
  • Poldelta antibody
  • Pol delta antibody

Protein level used designations for POLD1

CG5949-PA , DNA polymerase delta , DNA polymerase-delta , DNApol-delta-PA , lethal (3) 72Ac , DNA polymerase delta catalytic subunit , DNA-dependent DNA polymerase , DNA polymerase delta subunit 3 , polymerase (DNA directed), delta 3 , polymerase (DNA-directed), delta 3, accessory subunit , DNA-directed DNA polymerase delta 3 , DNA polymerase subunit delta 3 , polymerase (DNA directed), delta 1, catalytic subunit 125kDa , DNA-directed DNA polymerase delta 1 , DNA polymerase delta catalytic subunit-like , CDC2 homolog , DNA polymerase subunit delta p125 , DNA polymerase delta 1, catalytic domain , DNA polymerase delta, catalytic subunit

GENE ID SPECIES
39746 Drosophila melanogaster
548092 Glycine max
419053 Gallus gallus
451422 Pan troglodytes
476806 Canis lupus familiaris
549310 Xenopus (Silurana) tropicalis
693601 Macaca mulatta
100051966 Equus caballus
456228 Pan troglodytes
610047 Canis lupus familiaris
719262 Macaca mulatta
734063 Xenopus (Silurana) tropicalis
100052455 Equus caballus
100389890 Callithrix jacchus
100456571 Pongo abelii
100525752 Sus scrofa
5424 Homo sapiens
18971 Mus musculus
59294 Rattus norvegicus
281990 Bos taurus
Selected quality suppliers for anti-Polymerase (DNA Directed), delta 1, Catalytic Subunit 125kDa (POLD1) Antibodies
Did you look for something else?