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Browse our POLD2 Proteins (POLD2)

Full name:
Polymerase (DNA Directed), delta 2, Accessory Subunit Proteins (POLD2)
On www.antibodies-online.com are 9 Polymerase (DNA Directed), delta 2, Accessory Subunit (POLD2) Proteins from 4 different suppliers available. Additionally we are shipping POLD2 Antibodies (28) and many more products for this protein. A total of 41 POLD2 products are currently listed.
Synonyms:
50kDa, cdc1, p50, po1D2
list all proteins Gene Name GeneID UniProt
POLD2 5425 P49005
POLD2 289758 Q6AXY4
POLD2 18972 O35654

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POLD2 Proteins (POLD2) by Origin

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More Proteins for POLD2 Interaction Partners

Human Polymerase (DNA Directed), delta 2, Accessory Subunit (POLD2) interaction partners

  1. Inhibition of DNA polymerases a, delra and e by AFP (show AFP Proteins) promoter-driven artificial microRNAs may lead to effective growth arrest of AFP (show AFP Proteins)-positive HCC (show FAM126A Proteins) cells,as novel strategy for gene therapy

  2. The results show that the FF483-484 amino acids in the human Poleta (designated F1 motif) are necessary for the interaction of this polymerase with POLD2, the B subunit of the replicative DNA polymerase delta (show POLD1 Proteins), both in vitro and in vivo.

  3. DNA polymerase delta catalytic subunit (show POLD1 Proteins) p125 (show XPC Proteins) induced by mutant type p53 (show TP53 Proteins) is associated with hepatocellular carcinoma invasion.

  4. Results suggest that POLD2 and KSP37 might be potential prognostic biomarkers.

  5. the interaction of PCNA (show PCNA Proteins) with DNA polymerase delta (show POLD1 Proteins) is mediated through the small subunit of the enzyme

  6. The association of PDIP38 (show POLDIP2 Proteins) with pol delta (show POLD1 Proteins) was shown to occur in calf thymus tissue and mammalian cell extracts by GST (show SLCO6A1 Proteins)-PDIP38 (show POLDIP2 Proteins) pull-down and coimmunoprecipitation experiments.

  7. As a first step towards understanding the functional importance of their regulatory subunit interactions, the three-dimensional structure of the p50 (show CD40 Proteins)-p66 (show POLD3 Proteins) heterodimer of human Pol delta (show POLD1 Proteins) has been solved using X-ray crystallography.

  8. the crystal structure of p50 (show CD40 Proteins)*p66 (show POLD3 Proteins)(N) complex featuring oligonucleotide binding and phosphodiesterase domains in p50 (show CD40 Proteins)

Mouse (Murine) Polymerase (DNA Directed), delta 2, Accessory Subunit (POLD2) interaction partners

  1. A direct interaction between Pold2 and PIAS2 (show PIAS2 Proteins) was confirmed by direct yeast two-hybrid.

  2. The association of PDIP38 (show POLDIP2 Proteins) with pol delta (show POLD1 Proteins) was shown to occur in calf thymus tissue and mammalian cell extracts by GST-PDIP38 (show POLDIP2 Proteins) pull-down and coimmunoprecipitation experiments.

POLD2 Protein Profile

Protein Summary

This gene encodes the 50-kDa catalytic subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. The encoded protein is required for the stimulation of DNA polymerase delta activity by the processivity cofactor proliferating cell nuclear antigen (PCNA). Expression of this gene may be a marker for ovarian carcinomas. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 5.

Alternative names and synonyms associated with POLD2

  • polymerase (DNA directed), delta 2, accessory subunit (POLD2)
  • polymerase (DNA directed), delta 2, accessory subunit (Pold2)
  • polymerase (DNA directed), delta 2, accessory subunit (pold2)
  • polymerase (DNA directed), delta 2, regulatory subunit (Pold2)
  • polymerase (DNA directed), delta 2, regulatory subunit 50kDa (POLD2)
  • 50kDa protein
  • cdc1 protein
  • p50 protein
  • po1D2 protein

Protein level used designations for POLD2

DNA polymerase delta subunit 2 , DNA polymerase delta subunit p50 , Pol delta B subunit (p50) , polymerase (DNA directed), delta 2, regulatory subunit 50kDa , DNA-directed DNA polymerase delta 2 , polymerase (DNA directed), delta 2, regulatory subunit , xlCdc1

GENE ID SPECIES
5425 Homo sapiens
289758 Rattus norvegicus
379793 Xenopus laevis
18972 Mus musculus
281991 Bos taurus
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