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POLD2 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

POLD2 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2729300
  • Target See all POLD2 Proteins
    POLD2 (Polymerase (DNA Directed), delta 2, Accessory Subunit (POLD2))
    Protein Type
    Recombinant
    Protein Characteristics
    Transcript Variant 2
    Origin
    • 5
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 3
    • 2
    • 2
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This POLD2 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human POLD2 (transcript variant 2) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product POLD2 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    POLD2 (Polymerase (DNA Directed), delta 2, Accessory Subunit (POLD2))
    Alternative Name
    Pold2 (POLD2 Products)
    Synonyms
    50kDa Protein, p50 Protein, po1D2 Protein, cdc1 Protein, si:dz150f13.3 Protein, zgc:55633 Protein, zgc:77043 Protein, DNA polymerase delta 2, accessory subunit Protein, polymerase (DNA directed), delta 2, regulatory subunit Protein, polymerase (DNA directed), delta 2, accessory subunit L homeolog Protein, POLD2 Protein, Pold2 Protein, pold2.L Protein, pold2 Protein
    Background
    This gene encodes the 50- kDa catalytic subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. The encoded protein is required for the stimulation of DNA polymerase delta activity by the processivity cofactor proliferating cell nuclear antigen (PCNA). Expression of this gene may be a marker for ovarian carcinomas. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 5.
    Molecular Weight
    51.1 kDa
    NCBI Accession
    NP_006221
    Pathways
    Telomere Maintenance, DNA Damage Repair, DNA Replication, Synthesis of DNA
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