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Browse our Coq7 Proteins (Coq7)

Full name:
Coenzyme Q Biosynthesis Protein 7 Proteins (Coq7)
On www.antibodies-online.com are 9 Coenzyme Q Biosynthesis Protein 7 (Coq7) Proteins from 6 different suppliers available. Additionally we are shipping Coq7 Antibodies (40) and many more products for this protein. A total of 54 Coq7 products are currently listed.
Synonyms:
CAT5, clk-1, CLK1
list all proteins Gene Name GeneID UniProt
Coq7 10229 Q99807
Rat Coq7 Coq7 25249  
Coq7 12850 P97478

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Coq7 Proteins (Coq7) by Origin

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Top referenced Coq7 Proteins

  1. Human Coq7 Protein expressed in Human Cells - ABIN2005107 : Ewbank, Barnes, Lakowski, Lussier, Bussey, Hekimi: Structural and functional conservation of the Caenorhabditis elegans timing gene clk-1. in Science (New York, N.Y.) 1997 (PubMed)
    Show all 5 references for ABIN2005107

More Proteins for Coq7 Interaction Partners

Human Coenzyme Q Biosynthesis Protein 7 (Coq7) interaction partners

  1. Mitochondrial COQ9 (show COQ9 Proteins) is a lipid-binding protein that associates with COQ7 to enable coenzyme Q biosynthesis.

  2. action of clioquinol on several age-dependent neurodegenerative diseases with distinct etiologies might result from a slowing down of the aging process through action of the drug on CLK-1 (show CDK11B Proteins).

  3. The siRNA-mediated knock down leads to an increase in cytoplasmic superoxide dismutase (SOD1 (show SOD1 Proteins)) mRNA levels and activity

Mouse (Murine) Coenzyme Q Biosynthesis Protein 7 (Coq7) interaction partners

  1. Mitochondrial COQ9 (show COQ9 Proteins) is a lipid-binding protein that associates with COQ7 to enable coenzyme Q biosynthesis.

  2. These findings indicate that MCLK1 (also known as Coq7) regulates both coenzyme Q synthesis and distribution within mitochondrial membranes.

  3. CLK-1 protein has DNA binding activity specific to O(L) region of mitochondrial DNA.

  4. clk-1 deficiency induces apoptosis associated with mitochondrial dysfunction in mouse embryos.

  5. action of clioquinol on several age-dependent neurodegenerative diseases with distinct etiologies might result from a slowing down of the aging process through action of the drug on CLK-1.

  6. Reduction in COQ7 levels gradually prevents the deterioration of mitochondrial function and associated increase of global oxidative stress that is normally observed in Sod2 (show SOD2 Proteins)(+/-) mutants.

Caenorhabditis elegans (C. elegans) Coenzyme Q Biosynthesis Protein 7 (Coq7) interaction partners

  1. Nuclear CLK-1 mediates a retrograde signalling pathway that is conserved from Caenorhabditis elegans to humans and is responsive to mitochondrial reactive oxygen species, thus acting as a barometer of oxidative metabolism.

  2. no measurable intrinsic ETC defect exists in clk-1 mitochondria. The data indicate that DMQ(9) specifically inhibits electron transfer from complex I to ubiquinone.

  3. Prolonged life span of Clk mutants cannot be attributed to reduced metabolic rate or an increased activity of the major antioxidant enzymes catalase and SOD.

  4. Complementation of Escherichia coli ubiF mutation by Caenorhabditis elegans CLK-1.

  5. Caenorhabditis elegans clk-1 mutants are sensitive to ubiquinone side-chain length

  6. in maternally resqued animals, the effect of clk-1 mutations on adult lifespan in uncoupled from their effects on development and reproduction

  7. differential fertility of clk-1 mutant nematodes fed Q isoforms may result from changes in Q localization, altered recognition by Q-binding proteins, and/or potential defects in mitochondrial function resulting from the mutant CLK-1 polypeptide itself.

  8. Suppressors of the missense mutation of clk-1 were identified; each mutant suppresses a different subset of phenotypes.

  9. action of clioquinol on several age-dependent neurodegenerative diseases with distinct etiologies might result from a slowing down of the aging process through action of the drug on CLK-1.

Coq7 Protein Profile

Protein Summary

The protein encoded by this gene is similar to a mitochondrial di-iron containing hydroxylase in Saccharomyces cerevisiae that is involved with ubiquinone biosynthesis. Mutations in the yeast gene lead to slower development and longer life span. Alternatively spliced transcript variants have been found for this gene.

Alternative names and synonyms associated with Coq7

  • coenzyme Q7 homolog, ubiquinone (yeast) (COQ7)
  • coenzyme Q7 homolog, ubiquinone (yeast) (Coq7)
  • demethyl-Q 7 (Coq7)
  • Protein CLK-1 (clk-1)
  • CAT5 protein
  • clk-1 protein
  • CLK1 protein

Protein level used designations for Coq7

COQ7 coenzyme Q, 7 homolog ubiquinone , coenzyme Q biosynthesis protein 7 homolog , placental protein KG-20 , timing protein clk-1 homolog , ubiquinone biosynthesis protein COQ7 homolog , Coenzyme q (ubiquinone) biosynthetic enzyme (DHPB methyltransferase) 7 , demethyl-Q 7

GENE ID SPECIES
10229 Homo sapiens
25249 Rattus norvegicus
504771 Bos taurus
12850 Mus musculus
175729 Caenorhabditis elegans
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