You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-Human Adenomatous Polyposis Coli antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended Adenomatous Polyposis Coli Antibody (supplied by: Log in to see )

Antigen
Adenomatous Polyposis Coli (APC) Antibodies
  • AI047805
  • APC1
  • AU020952
  • AW124434
  • BTPS2
  • CC1
  • dp2
  • DP2
  • DP2.5
  • dp2.5
  • DP3
  • dp3
  • fap
  • fpc
  • GS
  • mAPC
  • Min
  • PPP1R46
  • RATAPC
  • xapc
Reactivity
Human, Mouse (Murine), Rat (Rattus)
152
89
57
6
4
2
2
1
1
Host
Rabbit
142
33
15
2
Clonality
Polyclonal
Conjugate
Un-conjugated
9
8
6
4
4
4
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
129
61
61
48
44
27
23
22
13
4
2
1
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

It's quick and easy to submit your validation proposal. I want to validate this product

Learn more

Available images

Catalog No. ABIN271993
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.00089850504 ABIN265313 EIA IF IHC (p) WB Rabbit Log in to see Polyclonal
0.00089850504 ABIN373037 IHC (p) WB Rabbit C-Term Log in to see Polyclonal
0.00089850504 ABIN1686932 IHC (p) Rabbit IgG C-Term Log in to see Polyclonal
0.00089850504 ABIN1492008 IHC (p) Rabbit IgG Log in to see Polyclonal
0.00089850504 ABIN2878980 IHC (p) ELISA WB Rabbit IgG AA 2794-2843 Log in to see Polyclonal
0.00089850504 ABIN1686931 IHC (p) Rabbit IgG C-Term Log in to see Polyclonal
0.00089850504 ABIN1803997 IHC (p) IP WB Rabbit C-Term Log in to see Polyclonal
0.00089850504 ABIN2888780 IHC (p) ELISA Rabbit IgG AA 2020-2069 Log in to see Polyclonal
0.00089850504 ABIN372972 IHC (p) IP Rabbit C-Term Log in to see Polyclonal
0.00089850504 ABIN702550 IF (p) IHC (p) Rabbit IgG AA 2790-2843 Log in to see Polyclonal
0.00089850504 ABIN1731843 IHC (p) ELISA WB Rabbit IgG C-Term Log in to see Polyclonal
0.00089850504 ABIN2852374 IHC (p) IP WB Rabbit IgG C-Term Log in to see Polyclonal
0.00089850504 ABIN2616770 IHC (p) Mouse IgG1 AA 955-1382 Log in to see 1B12
0.00089850504 ABIN2616769 IHC (p) Mouse IgG1 AA 955-1382 Log in to see 2B8
0.00089850504 ABIN153070 ICC IHC (fro) IF IHC (p) IHC Mouse IgG2b AA 1-226 Log in to see CC-1
0.00089850504 ABIN1858037 ICC IHC (fro) IHC (p) ELISA WB Rabbit IgG AA 2634-2843 Log in to see Polyclonal
0.00089850504 ABIN702552 IHC (p) Biotin Rabbit IgG AA 2790-2843 Log in to see Polyclonal
0.00089850504 ABIN702559 IHC (p) HRP Rabbit IgG AA 2790-2843 Log in to see Polyclonal
0.00089850504 ABIN1700096 IHC (p) WB Biotin Rabbit IgG pSer2054 Log in to see Polyclonal
0.00089850504 ABIN1711113 IHC (p) WB HRP Rabbit IgG pSer2054 Log in to see Polyclonal

Similar anti-Adenomatous Polyposis Coli Antibodies

Application / Reactivity Human Mouse (Murine) Rat (Rattus)
Western Blotting (WB) 97 Antibodies 69 Antibodies 39 Antibodies
Proximity Ligation Assay (PLA) 2 Antibodies
Immunoprecipitation (IP) 14 Antibodies 5 Antibodies 5 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 49 Antibodies 28 Antibodies 27 Antibodies
Immunohistochemistry (IHC) 64 Antibodies 30 Antibodies 31 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 23 Antibodies 2 Antibodies 1 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 22 Antibodies 11 Antibodies

General

Antigen Adenomatous Polyposis Coli (APC) Antibodies
Reactivity Human, Mouse (Murine), Rat (Rattus)
(152), (89), (57), (6), (4), (2), (2), (1), (1)
Host Rabbit
(142), (33), (15), (2)
Clonality
Polyclonal
Conjugate Un-conjugated
(9), (8), (6), (4), (4), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1)
Application Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(129), (61), (61), (48), (44), (27), (23), (22), (13), (4), (2), (1), (1)
Supplier Log in to see

Product details

Target details Application Details Handling Images
Specificity This antibody detects endogenous levels of APC protein. (region surrounding Lys2050)
Cross-Reactivity (Details) Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Purity > 95 % pure by SDS-PAGE

Target details

Product details Application Details Handling Images back to top
Antigen
Alternative Name APC / DP2.5 (APC Antibody Abstract)
Background Adenomatous polyposis coli (APC) is a protein that plays a critical role in several cellular processes. APC is a tumor suppressor, regulates cell division, helps ensure that the number of chromosomes in a cell is correct following cell division and associates with other proteins involved in cell attachment and signaling. APC regulates ß-catenin levels through Wnt-signaling and is involved in actin cytoskeletal integrity, cell-cell adhesion and cell migration. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product.Synonyms: Adenomatous polyposis coli protein, Deleted in polyposis 2.5
Molecular Weight approx. 310 kDa
Gene ID 324
NCBI Accession NP_000029
UniProt P25054
Research Area Coagulation
Pathways WNT Signaling

Application Details

Product details Target details Handling Images back to top
Application Notes ELISA: 1: 1000approx. 1: 5000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product details Target details Application Details Images back to top
Concentration 1,0 mg/mL
Buffer Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice DO NOT FREEZE!
Storage 4 °C
Storage Comment Store the antibody undiluted at 2-8 °C.

Images

Product details Target details Application Details Handling back to top
Supplier Images
 image for anti-Adenomatous Polyposis Coli (APC) antibody (ABIN271993) anti-Adenomatous Polyposis Coli (APC) antibody