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ABCB11 Products

(ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 11 (ABCB11))
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is the major canalicular bile salt export pump in man. Mutations in this gene cause a form of progressive familial intrahepatic cholestases which are a group of inherited disorders with severe cholestatic liver disease from early infancy. [provided by RefSeq, Jul 2008].

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Featured ABCB11 Categories

ABCB11 Antibodies

High quality antibodies with extensive validation data.

ABCB11 ELISA Kits

Reliable ELISA kits for a wide range of species.

ABCB11 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended ABCB11 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (3)
Cat. No. ABIN7444397
Quantity 100 μL
Datasheet Datasheet
Reactivity Rat
Application ELISA, IHC (p)
Validations
  • (3)
Cat. No. ABIN675848
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC (p)
Validations
  • (2)
  • (2)
Cat. No. ABIN390059
Quantity 400 μL
Datasheet Datasheet

Recommended ABCB11 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6965067
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN5593393
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method
Validations
Cat. No. ABIN1123874
Quantity 96 tests
Datasheet Datasheet

Recommended ABCB11 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3088035
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3088034
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3130495
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our ABCB11 products

Bagheri, Ebrahimi, Abbasi, Atashsokhan, Salmani, Zamani: "Effect of Preoperative Visitation by Operating Room Staff on Preoperative Anxiety in Patients Receiving Elective Hernia Surgery." in: Journal of perianesthesia nursing : official journal of the American Society of PeriAnesthesia Nurses, Vol. 34, Issue 2, pp. 272-280, (2019) (PubMed).

Blackmore, Knisely, Hartley, McKay, Gissen, Marcus, Shawcross: "Polymorphisms in ABCB11 and ATP8B1 Associated with Development of Severe Intrahepatic Cholestasis in Hodgkin's Lymphoma." in: Journal of clinical and experimental hepatology, Vol. 3, Issue 2, pp. 159-61, (2015) (PubMed).

Sambrotta, Strautnieks, Papouli, Rushton, Clark, Parry, Logan, Newbury, Kamath, Ling, Grammatikopoulos, Wagner, Magee, Sokol, Mieli-Vergani, Smith, Johnson, McClean, Simpson, Knisely, Bull, Thompson: "Mutations in TJP2 cause progressive cholestatic liver disease." in: Nature genetics, Vol. 46, Issue 4, pp. 326-8, (2014) (PubMed).

Bochkis, Rubins, White, Furth, Friedman, Kaestner: "Hepatocyte-specific ablation of Foxa2 alters bile acid homeostasis and results in endoplasmic reticulum stress." in: Nature medicine, Vol. 14, Issue 8, pp. 828-36, (2008) (PubMed).

Chen, Chang, Hsu, Ni, Hsu, Lee, Jeng, Shau, Chang: "FIC1 and BSEP defects in Taiwanese patients with chronic intrahepatic cholestasis with low gamma-glutamyltranspeptidase levels." in: The Journal of pediatrics, Vol. 140, Issue 1, pp. 119-24, (2002) (PubMed).

Saito, Iida, Sekine, Miura, Ogawa, Kawauchi, Higuchi, Nakamura: "Three hundred twenty-six genetic variations in genes encoding nine members of ATP-binding cassette, subfamily B (ABCB/MDR/TAP), in the Japanese population." in: Journal of human genetics, Vol. 47, Issue 1, pp. 38-50, (2002) (PubMed).

Truog: ""Do-not-resuscitate" orders during anesthesia and surgery." in: Anesthesiology, Vol. 74, Issue 3, pp. 606-8, (1991) (PubMed).

Synonyms and alternative names related to ABCB11

ATP binding cassette subfamily B member 11 (ABCB11), bile salt export pump (LOC100489744), bile salt export pump (LOC100565276), bile salt export pump (EDI_111220), bile salt export pump (EDI_272930), bile salt export pump (abcb11), ATP binding cassette subfamily B member 11 (Abcb11), ATP-binding cassette, sub-family B (MDR/TAP), member 11 (Abcb11), ABC16, ABCB11, BRIC2, Bsep, BSEP, BSEP/SPGP, Lith1, PFIC-2, PFIC2, PGY4, SPGP, Spgp

Protein level used designations for ABCB11

  • ATP-binding cassette, sub-family B (MDR/TAP), member 11
  • bile salt export pump
  • bile salt export pump-like
  • ABC member 16, MDR/TAP subfamily
  • ATP-binding cassette sub-family B member 11
  • progressive familial intrahepatic cholestasis 2
  • sister p-glycoprotein
  • ATP-binding cassette, sub-family B, member 11
  • sister of P-glycoprotein
  • liver bile salt export pump
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