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Abeta 40 Products

(Amyloid beta 1-40 (Abeta 1-40))

Categories

This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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Featured Abeta 40 Categories

Abeta 40 Antibodies

High quality antibodies with extensive validation data.

Abeta 40 ELISA Kits

Reliable ELISA kits for a wide range of species.

Recommended Abeta 40 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse, Rat
Application IHC, IF
Validations
  • (1)
  • (3)
Cat. No. ABIN7073042
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IHC, WB, ELISA
Validations
  • (1)
  • (4)
Cat. No. ABIN1742443
Quantity 50 μg
Datasheet Datasheet
Reactivity Mouse, Rat
Application IHC
Validations
  • (2)
Cat. No. ABIN7233690
Quantity 200 μL
Datasheet Datasheet

Recommended Abeta 40 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method Quantitative Competition ELISA
Validations
  • (10)
  • (1)
Cat. No. ABIN6953693
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (1)
Cat. No. ABIN6963637
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (3)
  • (1)
Cat. No. ABIN6963478
Quantity 96 tests
Datasheet Datasheet

Recommended Abeta 40 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7317787
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our Abeta 40 products

Leira, Carballo, Orlandi, Aldrey, Pías-Peleteiro, Moreno, Vázquez-Vázquez, Campos, DAiuto, Castillo, Sobrino, Blanco: "Periodontitis and systemic markers of neurodegeneration: A case-control study." in: Journal of clinical periodontology, Vol. 47, Issue 5, pp. 561-571, (2021) (PubMed).

Liu, Cao, Lin, Tan, Zhao, Guo, Tan: "Enhancement of Fear Extinction Memory and Resistance to Age-Related Cognitive Decline in Butyrylcholinesterase Knockout Mice and (R)-Bambuterol Treated Mice." in: Biology, Vol. 10, Issue 5, (2021) (PubMed).

Li, Chang, Lin, Chen, Lu, Lee, Chen, Chen, Chen, Lin: "Prevention of Early Alzheimer's Disease by Erinacine A-Enriched Hericium erinaceus Mycelia Pilot Double-Blind Placebo-Controlled Study." in: Frontiers in aging neuroscience, Vol. 12, pp. 155, (2020) (PubMed).

Houben, Bitorina, Oligschlaeger, Jeurissen, Rensen, Köhler, Westerterp, Lütjohann, Theys, Romano, Plat, Shiri-Sverdlov: "Sex-opposed inflammatory effects of 27-hydroxycholesterol are mediated via differences in estrogen signaling." in: The Journal of pathology, Vol. 251, Issue 4, pp. 429-439, (2020) (PubMed).

Grewal, Reutzel, Dilberger, Hein, Zotzel, Marx, Tretzel, Sarafeddinov, Fuchs, Eckert: "Purified oleocanthal and ligstroside protect against mitochondrial dysfunction in models of early Alzheimer's disease and brain ageing." in: Experimental neurology, Vol. 328, pp. 113248, (2020) (PubMed).

Wan, Zhang, Luo, Xu, Huang, Yang, Liu, Mahaman, Ke, Wang, Liu, Wang, Shu, Wang: "Codonopsis pilosula polysaccharide attenuates Aβ toxicity and cognitive defects in APP/PS1 mice." in: Aging, Vol. 12, Issue 13, pp. 13422-13436, (2020) (PubMed).

Xiong, Li, Han, Zhou, Zhang, Tian, Tang, Li: "Study of mitophagy and ATP-related metabolomics based on β-amyloid levels in Alzheimer's disease." in: Experimental cell research, Vol. 396, Issue 1, pp. 112266, (2020) (PubMed).

Leira, Iglesias-Rey, Gómez-Lado, Aguiar, Campos, DAiuto, Castillo, Blanco, Sobrino: "Porphyromonas gingivalis lipopolysaccharide-induced periodontitis and serum amyloid-beta peptides." in: Archives of oral biology, Vol. 99, pp. 120-125, (2019) (PubMed).

Zhang, Wang, Niu: "Effect of Aluminum-Maltolate on the Content of Aβ Protein and the Expression of ApoER2, VLDLRs, and LRP1 in PC12-ApoE4 Cells." in: Neurotoxicity research, Vol. 35, Issue 4, pp. 931-944, (2019) (PubMed).

Dubey, Gulati, Ray: "Amelioration by nitric oxide (NO) mimetics on neurobehavioral and biochemical changes in experimental model of Alzheimer's disease in rats." in: Neurotoxicology, Vol. 66, pp. 58-65, (2019) (PubMed).

Synonyms and alternative names related to Abeta 40

amyloid beta precursor protein (APP), AAA, ABETA, ABPP, AD1, APPI, CTFgamma, CVAP, PN-II, PN2

Protein level used designations for Abeta 40

  • alzheimer disease amyloid protein
  • amyloid beta A4 protein
  • beta-amyloid peptide
  • cerebral vascular amyloid peptide
  • peptidase nexin-II
  • preA4
  • protease nexin-II
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