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ACRV1 encodes a testis-specific, differentiation antigen, acrosomal vesicle protein 1, that arises within the acrosomal vesicle during spermatogenesis, and is associated with the acrosomal membranes and matrix of mature sperm. Additionally we are shipping Acrosomal Vesicle Protein 1 Antibodies (83) and and many more products for this protein.
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ACRV1 protein was predominantly located in round and elongated spermatids in testes, indicating that ACRV1 may play an important role in mammalian spermatogenesis
Loss of ACRV1 led to the progression of pancreatic intraductal carcinoma in mouse models.
Using RT-PCR analysis of mouse ACRV1, we determined that ACRV1 was expressed specifically in the testis, and its expression began at days 35.
TDP-43 is a transcriptional repressor and that it regulates spatiotemporal expression of the acrv1 gene during spermatogenesis.
A novel CpG-free vertebrate insulator silences the testis-specific SP-10 gene in somatic tissues: role for TDP-43 in insulator function.
we propose that NF45 and NF90 have the potential to activate SP-10 gene transcription, and that a chromatin modification event must occur first in order to provide access to these transcription factors.
This gene encodes a testis-specific, differentiation antigen, acrosomal vesicle protein 1, that arises within the acrosomal vesicle during spermatogenesis, and is associated with the acrosomal membranes and matrix of mature sperm. The acrosomal vesicle protein 1 may be involved in sperm-zona binding or penetration. Alternatively spliced transcript variants have been described.
acrosomal vesicle protein 1
, acrosomal protein SP-10
, sperm protein 10
, sperm membrane protein