anti-Alcohol Dehydrogenase 1A (Class I), alpha Polypeptide (ADH1A) Antibodies

ADH1A encodes a member of the alcohol dehydrogenase family. Additionally we are shipping ADH1A Kits (17) and ADH1A Proteins (10) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ADH1A 11522 P00329
ADH1A 24172 P06757
ADH1A 124 P07327
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Top anti-ADH1A Antibodies at antibodies-online.com

Showing 10 out of 43 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Dog Rabbit Un-conjugated WB WB Suggested Anti-ADH1A Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:62500  Positive Control:  Human Liver 100 μL 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-ADH1A Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:12500  Positive Control:  Human Liver 100 μL 2 to 3 Days
$319.00
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of ADH1A using anti- ADH1A antibody .  Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each  Lane was loaded with 50ug of sample under reducing conditions.   Lane 1: rat lung tissue lysates,   Lane 2: mouse liver tissue lysates,   Lane 3: HEPG2 whole cell lysates. After Electrophoresis, proteins were transferred to a Nitrocellulose membrane at 150mA for 50-90 minutes. Blocked the membrane with 5% Non-fat Milk/ TBS for 1.5 hour at RT. The membrane was incubated with rabbit anti- ADH1A antigen affinity purified polyclonal antibody (Catalog # ) at 0.5 µg/mL overnight at 4°C, then washed with TBS-0.1%Tween 3 times with 5 minutes each and probed with a goat anti-rabbit IgG-HRP secondary antibody at a dilution of 1:10000 for 1.5 hour at RT. The signal is developed using an Enhanced Chemiluminescent detection (ECL) kit (Catalog # EK1002) with Tanon 5200 system. A specific band was detected for ADH1A at approximately 40KD. The expected band size for ADH1A is at 40KD. IHC analysis of ADH1A using anti- ADH1A antibody . ADH1A was detected in paraffin-embedded section of human liver cancer tissues. Heat mediated antigen retrieval was performed in citrate buffer (pH6, epitope retrieval solution) for 20 mins. The tissue section was blocked with 10% goat serum. The tissue section was then incubated with 1µg/ml rabbit anti- ADH1A Antibody  overnight at 4°C. Biotinylated goat anti-rabbit IgG was used as secondary antibody and incubated for 30 minutes at 37°C. The tissue section was developed using Strepavidin-Biotin-Complex (SABC)(Catalog # SA1022) with DAB as the chromogen. 100 μg 4 to 6 Days
$280.00
Details
Human Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$551.83
Details
Dog Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$581.17
Details
Chimpanzee Goat Un-conjugated WB   0.1 mg 4 to 8 Days
$462.00
Details
Human Goat Un-conjugated IHC, ELISA, WB 0.1 mg 2 to 3 Days
$515.63
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL 2 to 3 Days
$446.88
Details
Human Mouse Un-conjugated ICC   200 μg 11 to 14 Days
$522.50
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (34.69 KDa) . 50 μL 11 to 12 Days
$238.67
Details

More Antibodies against ADH1A Interaction Partners

Mouse (Murine) Alcohol Dehydrogenase 1A (Class I), alpha Polypeptide (ADH1A) interaction partners

  1. It is responsible for systemic alcohol metabolism.

  2. Overexpression of an ADH1 transgene protected against tunicamycin-induced cardiac dysfunction through attenuation of ER stress, oxidative stress, and PTEN-Akt-mTOR regulated autophagy.

  3. Data indicate a potential change in aldehyde dehydrogenase (ALDH) activity of proliferating beta cells during pregnancy.

  4. regulation of human class I alcohol dehydrogenases by bile acids

  5. This study demonistrated that adh1 knockout mice as possible rodent models for presymptomatic Parkinson's disease.

  6. Distinct retinoid metabolic functions for alcohol dehydrogenase genes Adh1 and Adh4 in protection against vitamin A toxicity or deficiency revealed in double null mutant mice

  7. Retinol/ethanol drug interaction during acute alcohol intoxication in mice involves inhibition of retinol metabolism to retinoic acid by alcohol dehydrogenase

  8. ADH1 functions as the primary enzyme responsible for efficient oxidative clearance of excess retinol, thus providing protection and increased survival during vitamin A toxicity

  9. Results describe the expression patterns of alcohol dehydrogenases I, III, and IV in adult rat, mouse and human tissues using radioactive oligonucleotide in situ hybridization.

  10. Crbp1-/- mice also exhibited increased metabolism of a dose of retinol into retinoic acid, and this increased metabolism was not observed in Crbp1-/-/Adh1-/- mice

  11. Cellular expression of Adh1 in the GI tract was studied.

  12. After chronic ethanol consumption, the activity of the MEOS increases, with an associated rise in cytochrome P450, especially CYP2E1, most conclusively shown in alcohol dehydrogenase negative deer mice.

  13. Liver disease in the alcoholic is due not only to malnutrition but also to ethanol's hepatotoxicity linked to its metabolism by means of the alcohol dehydrogenase and CYP2E1 pathways and the resulting production of toxic acetaldehyde.

  14. The hepatic enzymatic systems involved in ethanol metabolism are alcohol dehydrogenase (ADH), aldehyde dehydrogenase (ALDH) and microsomal P4502E1 (CYP2E1).

  15. Ethanol at low concentrations is metabolized by low Km alcohol dehydrogenase and aldehyde dehydrogenase, both reactions resulting in the production of reduced nicotinamide adenine dinucleotide (NADH).

Human Alcohol Dehydrogenase 1A (Class I), alpha Polypeptide (ADH1A) interaction partners

  1. We demonstrated for the first time that rs1154402C>G change in in intron 1 of ADH5 might create a silencer, repressing ADH1A transcription via long-range interaction with ADH1A promoter

  2. High ADH expression is associated with Prostate Cancer.

  3. Results suggest a potential role of alcohol dehydrogenase (ADH) class I as a marker for renal cell carcinoma (RCC).

  4. Data indicate that the up-regulation of aldehyde dehydrogenase-1 (ALDH1) after neoadjuvant chemotherapy (NAC) predicts poor survival in locally advanced breast cancer.

  5. Unde-rexpression of the ADH1 gene, which influences the transformation of the extracellular matrix, plays a probable role in the etiology of uterine fibroid.

  6. high levels of ADH1 transcription are implicated in fluconazole resistance in C. albicans and that the mRNA expression levels of ADH1 are positively correlated with those of CDR1, CDR2 and FLU1.

  7. common ADH variants conferred risk for both schizophrenia in African-Americans and autism in European-Americans.

  8. High ADH1 is associated with endometrial cancer.

  9. ADH1A variation predisposes to personality traits and substance dependence

  10. Structural aspects that influence dimer-tetramer formation.

  11. GATA-2 and HNF-3beta regulate the human alcohol dehydrogenase 1A (ADH1A) gene.

  12. The oxidative pathway of ethanol metabolism via ADH and ALDH does not play a role in pancreatic carcinogenesis.

  13. Alleles of ADH7 SNPs were associated with the early stages of alcohol metabolism, with additional effects in the ADH1A, ADH1B and ADH4 regions.

ADH1A Antigen Profile

Protein Summary

This gene encodes a member of the alcohol dehydrogenase family. The encoded protein is the alpha subunit of class I alcohol dehydrogenase, which consists of several homo- and heterodimers of alpha, beta and gamma subunits. Alcohol dehydrogenases catalyze the oxidation of alcohols to aldehydes. This gene is active in the liver in early fetal life but only weakly active in adult liver. This gene is found in a cluster with six additional alcohol dehydrogenase genes, including those encoding the beta and gamma subunits, on the long arm of chromosome 4. Mutations in this gene may contribute to variation in certain personality traits and substance dependence.

Gene names and symbols associated with ADH1A

  • alcohol dehydrogenase 1 (adh1) antibody
  • alcohol dehydrogenase 1A (LOC744064) antibody
  • alcohol dehydrogenase ADH1 (ADH1) antibody
  • Alcohol dehydrogenase 1 (Dvir\Adh1) antibody
  • alcohol dehydrogenase 1 (class I) (Adh1) antibody
  • alcohol dehydrogenase 1A (class I), alpha polypeptide (ADH1A) antibody
  • ADC1 antibody
  • Adh antibody
  • Adh-1 antibody
  • Adh-1-t antibody
  • Adh-1e antibody
  • Adh-1t antibody
  • Adh-3e antibody
  • ADH-AA antibody
  • ADH1 antibody
  • Adh1-e antibody
  • Adh1-t antibody
  • Adh1a antibody
  • Adh1c antibody
  • Adh1tl antibody
  • Adh3-e antibody
  • AI194826 antibody
  • Dvir\\Adh antibody
  • Dvir\\GJ18208 antibody
  • dvir_GLEANR_2771 antibody
  • GJ18208 antibody

Protein level used designations for ADH1A

class I alcohol dehydrogenase, alpha subunit , Adh1-PA , Dvir\\Adh1-PA , Dvir\\GJ18208-PA , GJ18208-PA , alcohol dehydrogenase , alcohol dehydrogenase 1 , ADH-A2 , alcohol dehydrogenase 1 temporal, liver , alcohol dehydrogenase 1, complex , alcohol dehydrogenase 1, electrophoretic , alcohol dehydrogenase 3, electrophoretic , alcohol dehydrogenase A subunit , class I alcohol dehydrogenase , alcohol dehydrogenase (class I), alpha polypeptide , alcohol dehydrogenase 1C (class I), gamma polypeptide , ADH, alpha subunit , alcohol dehydrogenase 1 (class I), alpha polypeptide , alcohol dehydrogenase 1A , alcohol dehydrogenase subunit alpha , aldehyde reductase , alcohol dehydrogenase 1 (subunit A) , alchohol dehydrogenase 1A

GENE ID SPECIES
496861 Xenopus (Silurana) tropicalis
744064 Pan troglodytes
854068 Saccharomyces cerevisiae S288c
6634390 Drosophila virilis
11522 Mus musculus
24172 Rattus norvegicus
124 Homo sapiens
280982 Bos taurus
100009283 Oryctolagus cuniculus
707682 Macaca mulatta
100172370 Pongo abelii
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