Angiogenin, Ribonuclease, RNase A Family, 5 Proteins (ANG)

The protein encoded by ANG is an exceedingly potent mediator of new blood vessel formation. Additionally we are shipping Angiogenin Antibodies (153) and Angiogenin Kits (100) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ANG 283 P03950
ANG 11727 P21570
ANG 305843  
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Top Angiogenin Proteins at antibodies-online.com

Showing 10 out of 38 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$6,749.58
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$6,749.58
Details
Escherichia coli (E. coli) Human His tag Angiogenin, Ribonuclease, RNase A Family, 5 (ANG) (AA 26-147), (full length) protein (His tag) 50 μg Log in to see 13 to 16 Days
$217.80
Details
Escherichia coli (E. coli) Mouse His tag 100 μg Log in to see 15 to 18 Days
$675.00
Details
Escherichia coli (E. coli) Rat His tag,T7 tag 100 μg Log in to see 15 to 18 Days
$688.00
Details
Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 4 Days
$280.50
Details
Escherichia coli (E. coli) Human His tag Validation with Western Blot 10 μg Log in to see 4 to 8 Days
$504.90
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 11 Days
$814.00
Details
Escherichia coli (E. coli) Human His tag 100 μg Log in to see 13 to 16 Days
$400.00
Details
Escherichia coli (E. coli) Cow Un-conjugated SDS-PAGE analysis of Cow Angiogenin Protein. 100 μg Log in to see 11 to 18 Days
$724.89
Details

ANG Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , ,
, , ,
Mouse (Murine) ,
,
Rat (Rattus)

More Proteins for Angiogenin, Ribonuclease, RNase A Family, 5 (ANG) Interaction Partners

Human Angiogenin, Ribonuclease, RNase A Family, 5 (ANG) interaction partners

  1. In a hypoxic model of cell line ARPE-19, an increased expression level of ANG and induction of EMT accompanied with stabilization and nucleus translocation of HIF-1alpha. Blockage of HIF-1alpha signaling resulted in inhibition of high expression of ANG and EMT features.

  2. Taken together, we hypothesize that PGRN A9D leads to the retention of ANG in the cytoplasm to protect cells from PGRN A9D-induced apoptosis, implying that PGRN and ANG act in concert to regulate the progress of neurodegenerative disease.

  3. Angiogenin contributes to angiogenesis induced by Brain-derived neurotrophic factor (BDNF).

  4. Data show that phospholipase D2 (PLD2)-produced phosphatidic acid (PA) promoted cell invasion through the the expression of angiogenin (ANG) in clear cell renal cell carcinoma (ccRCC) cells.

  5. The results revealed that PCNA is predominantly localized in the cytoplasm, while hAng is distributed both in the nucleus and in the cytoplasm. hAng and PCNA colocalize in the cytoplasm, suggesting that they may interact in this compartment.

  6. RNase 5 suppressed p27 and up-regulated cyclin D1, D3, and E by activating PI3-kinase/Akt in CECs to initiate cell cycle progression

  7. When yeast genetic interaction partners held in common between human OPTN and ANG were validated in mammalian cells and zebrafish, MAP2K5 kinase emerged as a potential drug target for amyotrophic lateral sclerosis therapy

  8. There was a significant association between RNase 5 and histological differentiation in colon adenocarcinomas, but no association between RNase 5 and Necl 4 in gastric or colon adenocarcinomas

  9. Results continue to establish ANG as an oncoprotein and further reveal that ANG contributes to oncogenesis by the activation of MMP2 through modulation of DNMT3b functions.

  10. (31) RRR(33) and (50) KRSIK(54) motifs of angiogenin might play a critical role in the regulation of p53-mediated apoptosis and angiogenesis in cancer cells.

  11. Study shows that plexin-B2 (PLXNB2) is the functional receptor for ANG in endothelial, cancer, neuronal, and normal hematopoietic and leukemic stem and progenitor cells.

  12. Delivery of the therapeutic human genes VEGF and ANG using an adenoviral vector improved functional recovery after traumatic spinal cord injury in a rat model. Immunofluorescent analysis of the post-treatment spinal cord suggested that the positive effect of Ad5-VEGF+Ad5-ANG transduction on recovery of locomotor function may be due to the action of glial cells on motor neurons.

  13. Ang down-regulate the expression of Col-I, alpha-SMA and TGF-beta1/Smad2/3 and subsequently inhibits fibroblast-myofibroblast transition.

  14. Ang,Tie1 and Tie2 play roles in vascular development and pathogenesis of vascular diseases.[review]

  15. Results indicate that angiogenin (ANG) plays a critical role in regulating angiogenesis and follicle survival in xenografted human ovarian tissues.

  16. we found that ANG plays an important role in EMT in squamous cell lung carcinoma and may be a valuable therapeutic target for squamous cell lung carcinoma

  17. There is Lack of association between the Angiogenin (ANG) rs11701 polymorphism and amyotrophic lateral sclerosis risk.

  18. ANG plays a non-cell-autonomous role in regulation of hematopoiesis by simultaneously preserving hematopoietic stem/progenitor cells stemness and promoting myeloid-restricted progenitor cell proliferation.

  19. ANG K17I variant is rare in Caucasian patients and controls and increases the risk for amyotrophic lateral sclerosis

  20. ANG rs11701 variant is a genetic risk factor for Parkinson's disease in Taiwan population.Mutations in ANG are not a common cause for idiopathic Parkinson's disease.

Pig (Porcine) Angiogenin, Ribonuclease, RNase A Family, 5 (ANG) interaction partners

  1. Association analyses revealed the significant associations (P < 0.05) between the porcine ANG g. 149G>T polymorphism and mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), mean platelet volume (MPV) and platelet-large cell ratio (P-LCR).

Mouse (Murine) Angiogenin, Ribonuclease, RNase A Family, 5 (ANG) interaction partners

  1. A significant elevation of ANG expression level in a model of laser-induced choroidal neovascularization was demonstrated.

  2. ANG plays a non-cell-autonomous role in regulation of hematopoiesis by simultaneously preserving hematopoietic stem/progenitor cells stemness and promoting myeloid-restricted progenitor cell proliferation.

  3. angiogenin and ILK signaling pathway plays a pivotal role in mediating the inhibitory effects of RI on melanoma cells growth

  4. Our data provide new insights into the paracrine activities of angiogenin in the nervous system, and further highlight the critical role of non-neuronal cells in the pathogenesis of Amyotrophic lateral sclerosis

  5. RNase 4 and RNase 5/ang 1 are unique among the RNase A ribonuclease genes in that they maintain a complex gene locus that is conserved across species with transcription initiated from tissue-specific dual promoters followed by differential exon splicing.

  6. ANG plays an important role in neurite pathfinding and this has implications for amyotrophic lateral sclerosis.

  7. Angiogenin mRNA was expressed in murine skin in a hair-cycle dependent manner, with maximum levels observed at the late anagen.

  8. All three types of the ANG inhibitor suppress rRNA transcription of the prostate luminal epithelial cells and inhibit AKT-induced PIN, indicating an essential role of ANG in AKT-mediated cell proliferation and survival.

  9. Murine angiogenin mRNA and protein are upregulated in motoneurons in response to hypoxia, and that Hypoxia-Inducible Factor 1 is sufficient and required to upregulate angiogenin expression during hypoxia.

Cow (Bovine) Angiogenin, Ribonuclease, RNase A Family, 5 (ANG) interaction partners

  1. This study is the first to demonstrate that hypoxia upregulates Ang1 expression via HIF2alpha-mediated transcriptional activation in pericytes, which plays a key role in angiogenesis.

  2. rAAV-mediated angiogenin gene transfer induces angiogenesis and modifies left ventricular remodeling in rats with myocardial infafrction.

  3. bovine angiogenin is the substance mainly responsible for the inhibitory effect of bovine milk on osteoclast-mediated bone resorption

Angiogenin (ANG) Protein Profile

Protein Summary

The protein encoded by this gene is an exceedingly potent mediator of new blood vessel formation. It hydrolyzes cellular tRNAs resulting in decreased protein synthesis and is similar to pancreatic ribonuclease. Alternative splicing results in two transcript variants encoding the same protein. This gene and the gene that encodes ribonuclease, RNase A family, 4 share promoters and 5' exons. Each gene splices to a unique downstream exon that contains its complete coding region.

Gene names and symbols associated with ANG

  • angiogenin (ANG)
  • angiogenin, ribonuclease, RNase A family, 5 (Ang)
  • angiogenin, ribonuclease, RNase A family, 5 (ANG)
  • angiogenin (Ang)
  • AI385586 protein
  • ALS9 protein
  • ANG protein
  • ANG1 protein
  • HEL168 protein
  • RNASE4 protein
  • Rnase5 protein
  • Rnase5a protein

Protein level used designations for ANG

RNase 5 , angiogenin , epididymis luminal protein 168 , ribonuclease 5 , angiogenin, ribonuclease A family, member 1 , angiogenin-1 , angiogenin ribonuclease 1

GENE ID SPECIES
283 Homo sapiens
733639 Sus scrofa
11727 Mus musculus
777597 Bos taurus
305843 Rattus norvegicus
100354306 Oryctolagus cuniculus
100034041 Equus caballus
494026 Pan troglodytes
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