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ANXA8 encodes a member of the annexin family of evolutionarily conserved Ca2+ and phospholipid binding proteins. Additionally we are shipping Annexin VIII Proteins (15) and and many more products for this protein.
Showing 10 out of 44 products:
Human Polyclonal Annexin VIII Primary Antibody for WB - ABIN5518736
Salenius, Haapanen, Harju, Jokela, Riekkinen: Late carotid restenosis: aetiologic factors for recurrent carotid artery stenosis during long-term follow-up. in European journal of vascular surgery 1989
These findings identify Anxa8 (show ANXA8L2 Antibodies) as a regulator of late endosomes/lysosomes cholesterol balance.
We conclude that AnxA8 (show ANXA8L2 Antibodies) affects CD63 (show CD63 Antibodies)/VEGFR2 (show KDR Antibodies)/beta1 integrin complex formation, leading to hyperactivation of the VEGF-A (show VEGFA Antibodies) signal transduction pathway, and severely disturbed VEGF-A (show VEGFA Antibodies)-driven angiogenic sprouting.
Increased annexin A8 expression is associated with poor prognosis in early-stage pancreatic cancer.
High ANXA8 (show ANXA8L2 Antibodies) gene expression is associated with lymph node metastasis in oral squamous cell carcinoma.
Annexin A8 controls leukocyte recruitment to activated endothelial cells via cell surface delivery of CD63 (show CD63 Antibodies).
High ANXA8 (show ANXA8L2 Antibodies) expression is associated with pancreatic cancer.
Define a distinct bone-dependent genetic program associated with terminal osteoclast differentiation and identified Anxa8 as a gene strongly induced late in osteoclast differentiation, regulating formation of the cell's characteristic actin ring.
Annexin A8 is involved in mouse mammary gland involution and progression of human breast cancer
binds Ca2+-dependently and with high specificity to phosphatidylinositol (4,5)-bisphosphate (PtdIns(4,5)P2) and is also capable of interacting with F-actin
Data suggest that defective transport through the late endocytic pathway and imbalanced signaling in the absence of annexin A8 results from disturbed association of late endosomal membranes with actin and impaired endosome motility.
Annexin A8 identifies a subpopulation of transiently quiescent c-kit positive luminal progenitor cells of the ductal mammary epithelium.
ANXA8 protein is most abundant in stratified epithelia of the postnatal mouse. Its location in the suprabasal layers suggests that ANXA8 may be associated with the terminal differentiation of epithelial cells in these tissues.
This gene encodes a member of the annexin family of evolutionarily conserved Ca2+ and phospholipid binding proteins. The encoded protein may function as an an anticoagulant that indirectly inhibits the thromboplastin-specific complex. Overexpression of this gene has been associated with acute myelocytic leukemia. A highly similar duplicated copy of this gene is found in close proximity on the long arm of chromosome 10.
, annexin VIII
, vascular anticoagulant-beta
, annexin A8-like 1
, annexin A8-like 2
, annexin 8
, annexin A8
, annexin A8-like protein 1