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Positive regulator of neurite outgrowth by stabilizing myosin regulatory light chain (MRLC).
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CNPY2 isoform2 represents as a novel and valuable prognostic indicator for colorectal cancer patients.
These findings suggested that CNPY2 promoted cancer cell growth in renal cell carcinoma cells through regulating TP53 (show TP53 ELISA Kits) gene expression.
CNPY2 may play a critical role in colorectal cancer development by enhancing cell proliferation, migration, and angiogenesis and by inhibiting apoptosis through negative regulation of the p53 (show TP53 ELISA Kits) pathway
CNPY2 is a HIF-1alpha (show HIF1A ELISA Kits)-regulated, secreted angiogenic growth factor that promotes smooth muscle cell migration, proliferation, and tissue revascularization.
Our results are consistent with an important role of FGF21 (show FGF21 ELISA Kits) and Cnpy2/Msap in the regulation of LDLRs in cultured cells.
MSAP is a novel MIR-interacting protein that enhances neurite outgrowth and increases myosin regulatory light chain in fetal and adult brain.
Free CNPY2 then engages protein kinase (show CDK7 ELISA Kits) R-like endoplasmic reticulum kinase (PERK (show EIF2AK3 ELISA Kits)) to induce expression of the transcription factor C/EBP homologous protein (CHOP (show DDIT3 ELISA Kits)), thereby initiating the unfolded protein response.
The data demonstrate CNPY2 is widely distributed in tissues and suggest the protein has biological functions that have yet to be identified.
Positive regulator of neurite outgrowth by stabilizing myosin regulatory light chain (MRLC). It prevents MIR-mediated MRLC ubiquitination and its subsequent proteasomal degradation (By similarity).
MIR-interacting saposin-like protein
, canopy 2 homolog
, protein canopy homolog 2
, putative secreted protein Zsig9
, transmembrane protein 4
, putative secreted protein ZSIG9