ABIN412021
:
Bahl, Kim, Calcagno, Ghersi, Puzone, Celada, Selin, Welsh: IFN-induced attrition of CD8 T cells in the presence or absence of cognate antigen during the early stages of viral infections. in Journal of immunology (Baltimore, Md. : 1950) 2006
(PubMed)
Show all 9 Pubmed References
ABIN412023
:
Veschini, Belloni, Foglieni, Cangi, Ferrarini, Caligaris-Cappio, Ferrero: Hypoxia-inducible transcription factor-1 alpha determines sensitivity of endothelial cells to the proteosome inhibitor bortezomib. in Blood 2007
(PubMed)
Show all 6 Pubmed References
ABIN411788
:
Jin, Strich, Cooper: Slt2p phosphorylation induces cyclin C nuclear-to-cytoplasmic translocation in response to oxidative stress. in Molecular biology of the cell 2014
(PubMed)
Show all 4 Pubmed References
ABIN1882425
:
Lopez, Kelleher: Zip6-attenuation promotes epithelial-to-mesenchymal transition in ductal breast tumor (T47D) cells. in Experimental cell research 2010
(PubMed)
Show all 3 Pubmed References
ABIN1882428
:
Hayward, Eckerson, Collis: Thermal balance and survival time prediction of man in cold water. in Canadian journal of physiology and pharmacology 1975
(PubMed)
Show all 4 Pubmed References
ABIN1882426
:
Gugliesi, De Andrea, Mondini, Cappello, Giovarelli, Shoenfeld, Meroni, Gariglio, Landolfo: The proapoptotic activity of the Interferon-inducible gene IFI16 provides new insights into its etiopathogenetic role in autoimmunity. in Journal of autoimmunity 2010
(PubMed)
Show all 2 Pubmed References
drICE and dcp-1 function in cell death redundantly. However, dying neurons in a few clusters strictly required drICE but not dcp-1, but required drICE and dcp-1 when drICE activity was reduced via hypomorphic mutation.
Drosophila corazonin-producing interneuron programmed cell death utilizes dronc, strica, dcp-1, and ice
Autophagy suppresses Dcp-1-mediated apoptotic cell death, whereas Dcp-1 positively regulates autophagy, possibly through feedback regulation.
novel characteristic morphological features of egg chambers lacking both dcp-1 and pita functions in the germline cells; suggested an essential role of dcp-1 and/or pita during mid-oogenesis
A double-mutant analysis between drICE and death caspase-1 (dcp-1), another effector caspase, reveals that some cells (type I) strictly require drICE for apoptosis, whereas other cells (type II) require either drICE or dcp-1.
Data show that the effector caspase Dcp-1 and the inhibitor of apoptosis protein Bruce function to regulate both autophagy and starvation-induced cell death in Drosophila.
HeT-A mRNA is derepressed in mRNA degradation mutants dcp1, indicating that the enzyme also aid in removing full-length transcripts and/or decay intermediates.
Involved in the activation cascade of caspases responsible for apoptosis execution (By similarity). Proteolytically cleaves poly(ADP-ribose) polymerase (PARP). Loss of zygotic DCP-1 function causes larval lethality and melanotic tumors.
CG5370-PA , Dcp-1-PA , caspase , caspase 1 , caspase-1 , death caspase-1
GENE ID | SPECIES |
---|---|
37729 | Drosophila melanogaster |