Caspase Recruitment Domain Family, Member 16 Proteins (CARD16)

Caspase inhibitor. Additionally we are shipping CARD16 Antibodies (20) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CARD16 114769 Q5EG05
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Top CARD16 Proteins at

Showing 4 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see Available
Escherichia coli (E. coli) Human His tag Validation with Western Blot 50 μg Log in to see Available

CARD16 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, ,

More Proteins for Caspase Recruitment Domain Family, Member 16 (CARD16) Interaction Partners

Human Caspase Recruitment Domain Family, Member 16 (CARD16) interaction partners

  1. Expression of NOX4 (show NOX4 Proteins)/p22(phox (show CYBA Proteins)) as well as ROS (show ROS1 Proteins) production is enhanced by IL-1beta (show IL1B Proteins). On the other hand, the use of NOX4 (show NOX4 Proteins) inhibitors decreased IL-1beta (show IL1B Proteins)-induced collagenase synthesis by chondrocytes.

  2. Caspase-1 (show CASP1 Proteins)-mediated cell death is regulated, at least in part, by the balance of Rip2 and Cop; alterations of this balance may contribute to aberrant caspase-1 (show CASP1 Proteins)-mediated pathogenesis in Huntington's disease.

  3. Cop inhibition of cell death, at least to a certain extent, results from its interference with the activation of caspase-1 (show CASP1 Proteins) and caspase-4 (show CASP4 Proteins).

CARD16 Protein Profile

Protein Summary

Caspase inhibitor. Acts as a regulator of procaspase- 1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-interleukin-1 beta (IL1B) and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. Also induces NF-kappa-B activation during the pro- inflammatory cytokine response. Also able to inhibit CASP1- mediated neuronal cell death, TNF-alpha, hypoxia-, UV-, and staurosporine-mediated cell death but not ER stress-mediated cell death. Acts by preventing activation of caspases CASP1 and CASP4, possibly by preventing the interaction between CASP1 and RIPK2.

Gene names and symbols associated with CARD16

  • caspase recruitment domain family member 16 (CARD16)
  • COP protein
  • COP1 protein
  • PSEUDO-ICE protein

Protein level used designations for CARD16

CARD only domain-containing protein 1 , CARD only protein , caspase recruitment domain-containing protein 16 , caspase-1 dominant-negative inhibitor pseudo-ICE , caspase-1 inhibitor COP , pseudo interleukin-1 beta converting enzyme , pseudo interleukin-1beta converting enzyme

114769 Homo sapiens
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