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mouse homolog is a component of the centrosome [RGD, Feb 2006].. Additionally we are shipping Centrin 1 Antibodies (48) and many more products for this protein.
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Multidisciplinary approach showed that HsPrp40Ap interacts with centrin in vitro, supporting a coupled functional role for these proteins in pre-mRNA splicing.
The crystal structure exhibits three structural features, i.e. four Ca2 (show CA2 Proteins)+ equally occupied at each EF-hand motif, structural changes accompanying helix motion at the N- and C-lobes, and adoption of N-C type dimerization when Ca2 (show CA2 Proteins)+ binds to EF-hand I and II in the N-lobe (show LTF Proteins).
Immunostaining of seminiferous tubules revealed that cells in layer containing spermatogonia showed colocalization of SUMO-2 (show SUMO2 Proteins)/3 with centrin-1 in cytoplasmic spots. Binding of centrin-1 and SUMO-2 (show SUMO2 Proteins)/3 appears to be calcium dependent.
Calcium-dependent assembly of centrin-G-protein complex in photoreceptor cells
Cen1 and Cen2 contribute to the centrin-transducin (show GNAT1 Proteins) complex and potentially participate in the regulation of transducin (show GNAT1 Proteins) translocation through the photoreceptor cilium
important spectral and hydrodynamic characteristics of human Centrin-1, accounting that HsCentrin-1 has moderate affinity for Ca(2 (show CA2 Proteins)+). Centrin-1 does not gain structure as seen by far- and near-UV circular dichroism, rather there is a loss of ellipticity, though inconsiderable upon binding Ca(2 (show CA2 Proteins)+).
A chirality change in XPC (show XPC Proteins)- and Sfi1 (show SFI1 Proteins)-derived peptides affects their affinity for centrin.
CETN1 is overexpressed in breast cancer tissue and promotes cells'proliferation, tumor growth and metastasis.
These data demonstrate a functional role for CaM binding to CP110 and suggest that CP110 cooperates with CaM and centrin to regulate progression through cytokinesis.
mouse homolog is a component of the centrosome
centrin, EF-hand protein, 1
, centrin 1
, testis-specific murine centrin
, EF-hand protein
, calcium binding protein