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CHMP3 encodes a protein that sorts transmembrane proteins into lysosomes/vacuoles via the multivesicular body (MVB) pathway. Additionally we are shipping CHMP3 Proteins (14) and many more products for this protein.
Showing 10 out of 23 products:
Protein kinase CK2 (show CSNK2A1 Antibodies) alpha (show CSNK2A2 Antibodies) is involved in the phosphorylation of the ESCRT-III subunits CHMP3 and CHMP2B (show CHMP2B Antibodies), as well as of VPS4B/SKD1 (show vps4b Antibodies), an ATPase (show DNAH8 Antibodies) that mediates ESCRT-III disassembly.
tight coupling of ESCRT-III CHMP3 and AMSH (show STAMBP Antibodies) functions and provide insight into the regulation of ESCRT-III
data suggest that mac25/IGFBP-rP1 (show IGFBP7 Antibodies) and 25.1 (NEDF) may play a functional role in the NE differentiation of NSCLC cell lines and may provide a novel therapeutic target for treating lung cancers, in particular NSCLC with NE differentiation
ESCRT subunit is important for degradation of the epidermal growth factor receptor (EGFR (show EGFR Antibodies)) and for transport of the receptor from endosomes to lysosomes.
A dominant-negative version of CHMP3, which specifically prevents targeting of AMSH (STAMBP (show STAMBP Antibodies)) to endosomes, inhibits degradation but not internalization of epidermal growth factor receptor (show EGFR Antibodies).
Data demonstrate that the VPS24 gene gives rise to two functionally distinct proteins, one of which is involved in the ESCRT pathway and another novel protein that serves an anti-apoptotic role.
expression of dominant negative forms of Vps4 (show VPS4A Antibodies) and Vps24, two components of the MVB pathway, rresult in an impairment in infectious herpes simplex virus assembly/egress
UBPY (show USP8 Antibodies) MIT domain and another ubiquitin isopeptidase, AMSH (show STAMBP Antibodies), reveals common interactions with CHMP1A (show CHMP1A Antibodies) and CHMP1B (show CHMP1B Antibodies) but a distinct selectivity of AMSH (show STAMBP Antibodies) for CHMP3/VPS24, a core subunit of the ESCRT-III complex, and UBPY (show USP8 Antibodies) for CHMP7 (show CHMP7 Antibodies).
study found the ESCRT-III proteins CHMP2A (show CHMP2A Antibodies) & CHMP3 could assemble in vitro into helical tubular structures that expose their membrane interaction sites on the outside of the tubule; VPS4 (show VPS4A Antibodies) could bind on the inside of the tubule & disassemble the tubes
Data show that the N-terminal core domains of increased sodium tolerance-1 (IST1 (show IST1 Antibodies)) and charged multivesicular body protein-3 (CHMP3) form equivalent four-helix bundles, revealing that IST1 (show IST1 Antibodies) is a previously unrecognized ESCRT-III family member.
This gene encodes a protein that sorts transmembrane proteins into lysosomes/vacuoles via the multivesicular body (MVB) pathway. This protein, along with other soluble coiled-coil containing proteins, forms part of the ESCRT-III protein complex that binds to the endosomal membrane and recruits additional cofactors for protein sorting into the MVB. This protein may also co-immunoprecipitate with a member of the IFG-binding protein superfamily. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ring finger protein 103 (RNF103) gene.
charged multivesicular body protein 3
, chromatin-modifying protein 3
, vacuolar protein sorting 24 homolog
, vacuolar protein-sorting-associated protein 24
, Charged multivesicular body protein 3
, neuroendocrine differentiation factor
, vacuolar protein sorting-associated protein 24
, 25.1 protein
, CHMP family, member 3
, vacuolar protein sorting 24
, Vps24p protein