anti-Corneodesmosin (CDSN) Antibodies

CDSN encodes a protein found in corneodesmosomes, which localize to human epidermis and other cornified squamous epithelia. Additionally we are shipping Corneodesmosin Kits (38) and Corneodesmosin Proteins (10) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CDSN 1041 Q15517
CDSN 386463 Q7TPC1
CDSN 406198  
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Top anti-Corneodesmosin Antibodies at antibodies-online.com

Showing 10 out of 45 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Goat Un-conjugated ELISA, WB ABIN1686787 (1 µg/mL) staining of cell line A431 lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 6 to 7 Days
$429.84
Details
Human Rabbit Un-conjugated IHC, IHC (p) Immunohistochemistry: Corneodesmosin Antibody [NBP2-47501] - Analysis of human skin tissue. Shows strong cytoplasmic and membranous positivity in epidermal cells. Immunohistochemistry-Paraffin: Corneodesmosin Antibody  - Staining of human pancreas shows low expression as expected. 0.1 mL Log in to see 10 to 13 Days
$494.38
Details
Human Mouse Un-conjugated ELISA, WB Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (31.24 KDa) . Dilution: 1:500~1000 Detection limit for recombinant GST tagged CDSN is approximately 0.03ng/ml as a capture antibody. 100 μg Log in to see 8 to 11 Days
$527.50
Details
Human Sheep Biotin WB   50 μg Log in to see 11 to 14 Days
$1,211.83
Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged CDSN is approximately 0.03ng/ml as a capture antibody. Western Blot detection against Immunogen (31.24 KDa) . 100 μg Log in to see 11 to 12 Days
$364.00
Details
Human Rabbit Un-conjugated WB Western blot analysis of extracts of various cell lines, using CDSN antibody. 200 μL Log in to see 12 to 14 Days
$438.90
Details
Human Rabbit Un-conjugated IHC, ELISA, WB   100 μg Log in to see 11 to 14 Days
$537.17
Details
Human Goat Un-conjugated ELISA, WB   100 μg Log in to see 11 to 14 Days
$610.50
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (31.61 KDa) . 50 μL Log in to see 11 to 12 Days
$238.67
Details
Human Rabbit Un-conjugated WB   100 μL Log in to see 2 to 3 Days
$289.00
Details

Top referenced anti-Corneodesmosin Antibodies

  1. Human Monoclonal Corneodesmosin Primary Antibody for ELISA, WB - ABIN560318 : Fluhr, Lachmann, Baudouin, Msika, Darlenski, De Belilovsky, Bossert, Colomb, Burdin, Haftek: Development and organization of human stratum corneum after birth: electron microscopy isotropy score and immunocytochemical corneocyte labelling as epidermal maturation's markers in infancy. in The British journal of dermatology 2014 (PubMed)

More Antibodies against Corneodesmosin Interaction Partners

Human Corneodesmosin (CDSN) interaction partners

  1. results show, for the first time, the male-only associations of the PSORS1C3 gene with psoriasis risk and of the PSORS1C1/CDSN gene with severity of disease. However, the age dependent associations need to be validated in larger sample sizes as well as in other populations.

  2. We found that a burden of low-frequency coding variants in N4BP2, CDSN, PRTG, and AHRR were associated with increased risk of Nonsyndromic cleft lip with or without cleft palate (NSCL/P) . Low-frequency variants in other genes were associated with decreased risk of NSCL/P. These results demonstrate that low-frequency variants contribute to the genetic etiology of NSCL/P

  3. Investigated potential direct protein-protein interactions between six late cornified envelope (LCE) proteins and two corneodesmosin sequence variants. Partial colocalization of LCE2 and CDSN was observed in normal and psoriasis skin.

  4. we report a patient with PSD caused by a novel homozygous large deletion in the 6p21.3 region encompassing the CDSN gene, which abrogates CDSN expression

  5. Case Report: homozygous deletion of CDSN was considered to be responsible for generalized peeling skin disease.

  6. PSORS1C1/CDSN gene may play a pathogenic role in ankylosing spondylitis

  7. A nonsense mutation (C717G) in cDNA sequence of the CDSN gene was identified in all three patients of the family.

  8. CDSN -619C/T polymorphism may not be associated with susceptibility to psoriasis.

  9. CDSN plays a vital role in the structural and functional integrity of the epidermis and the hair follicle integrity by preventing the rupture of corneodesmosome.

  10. identified mRNA transcripts from three genes CDSN, LOR and KRT9, showing strong over-expression in skin samples relative to samples from forensic body fluids, making them suitable markers for skin identification

  11. Study of consangunity in a large family points to a homozygous nonesense mutation of the gene coding for corneodesmosin.

  12. The distribution of corneodesmosin on the surface of the stratum corneum was mapped at the nanoscale using atomic force microscopy.

  13. Data identifies hypotrichosis simplex of the scalp as a human amyloidosis related to the aggregation of natively unfolded (mut)CDSN polypeptides into amyloid fibrils.

  14. Lack of corneodesmosin causes an epidermal barrier defect supposed to account for the predisposition to atopic diseases.

  15. identified nonsense mutations in the gene CDSN (encoding corneodesmosin) in three families suffering from hypotrichosis simplex of the scalp

  16. non-glycosylated CDSN is able to spontaneously form large homo-oligomers in vitro and that the N-terminal glycine loop domain is necessary for the formation of these macromolecular complexes.

  17. Association analyses show that haplotypes bearing CDSN*971T maps to a RNA stability motif and confers psoriasis susceptibility in a wide range of ethnic groups.

  18. phenotype of Netherton syndrome is a consequence of desmosomal fragility associated with premature proteolysis of corneodesmosin

Mouse (Murine) Corneodesmosin (CDSN) interaction partners

  1. These results underscore the essential roles of CDSN in hair physiology and suggest functional relevance of CDSN gene polymorphisms to psoriasis susceptibility.

Corneodesmosin (CDSN) Antigen Profile

Protein Summary

This gene encodes a protein found in corneodesmosomes, which localize to human epidermis and other cornified squamous epithelia. During maturation of the cornified layers, the protein undergoes a series of cleavages, which are thought to be required for desquamation. The gene is located in the major histocompatibility complex (MHC) class I region on chromosome 6.

Gene names and symbols associated with anti-Corneodesmosin (CDSN) Antibodies

  • corneodesmosin (CDSN) antibody
  • corneodesmosin (Cdsn) antibody
  • AI747712 antibody
  • D6S586E antibody
  • HTSS antibody
  • HTSS1 antibody
  • PSS antibody
  • S antibody

Protein level used designations for anti-Corneodesmosin (CDSN) Antibodies

corneodesmosin , differentiated keratinocyte S protein , s protein

GENE ID SPECIES
100529069 Ornithorhynchus anatinus
1041 Homo sapiens
386463 Mus musculus
406198 Rattus norvegicus
100735014 Cavia porcellus
100144482 Sus scrofa
607062 Canis lupus familiaris
522351 Bos taurus
101109128 Ovis aries
714553 Macaca mulatta
462553 Pan troglodytes
100338321 Oryctolagus cuniculus
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