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Mitochondrial creatine (MtCK) kinase is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. Additionally we are shipping Creatine Kinase, Mitochondrial 1, Ubiquitous Antibodies (18) and Creatine Kinase, Mitochondrial 1, Ubiquitous Kits (5) and many more products for this protein.
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Mitochondrial creatine kinase (show CKMT2 Proteins) CKMT1 (show CKMT1B Proteins) is necessary for survival of EVI1 (show MECOM Proteins)-expressing cells in subjects with EVI1 (show MECOM Proteins)-positive AML (show RUNX1 Proteins).
LRRK2 can interact directly with uMtCK (show CKMT1B Proteins) to block its entry into mitochondria and its subsequent processing.
CKMT1 (show CKMT1B Proteins) is a key regulator of the permeability transition pore through a complex that is distinct from the classical permeability transition pore.
mitochondrial creatine kinase (show CKMT2 Proteins) expression in hepatocellular carcinoma may be caused by hepatocarcinogenesis per se but not by loss of mitochondrial integrity, of which ASB9 (show ASB9 Proteins) could be a negative regulator
The results indicated that uMtCK (show CKMT1B Proteins) expression is associated with a poor prognosis in breast cancer and might serve as a tumor marker.
Hypothalamic plasticity of neuropeptide Y (show NPY Proteins) is lacking in brain-type creatine kinase double knockout mice with defective thermoregulation
the knock-down of the mitochondrial creatine kinase (show CKMT2 Proteins)-1 (CKMT1) by RNA interference causes the dissipation of the mitochondrial membrane potential
UbCKmit was expressed selectively in neurons and localized in their mitochondria in dendrites, cell bodies
Data suggest that amyloid precursor protein (show APP Proteins) may regulate cellular energy levels and mitochondrial function via a direct interaction and stabilization of ubiquitous mitochondrial creatine kinase.
Mt-CK(-/-) on a C57BL/6 background do not develop LV hypertrophy or dysfunction even up to 1 year, and this may be explained by a compensatory increase in MM-CK activity and mitochondrial volume
Mitochondrial creatine (MtCK) kinase is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase\\\\; this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Ubiquitous mitochondrial creatine kinase has 80% homology with the coding exons of sarcomeric mitochondrial creatine kinase. Two genes located near each other on chromosome 15 have been identified which encode identical mitochondrial creatine kinase proteins.
, acidic-type mitochondrial creatine kinase
, creatine kinase U-type, mitochondrial
, creatine kinase, mitochondrial 1 (ubiquitous)
, ubiquitous mitochondrial creatine kinase
, creatine kinase, mitochondrial 1, ubiquitous
, Acidic-type mitochondrial creatine kinase
, Ubiquitous mitochondrial creatine kinase
, creatine kinase, mitochondrial 1B
, mitochondrial creatine kinase 1B