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HEI10 is a member of the E3 ubiquitin ligase family and functions in progression of the cell cycle through G(2)/M.[supplied by OMIM, Apr 2004].. Additionally we are shipping CCNB1IP1 Antibodies (59) and many more products for this protein.
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Interdependent localization of SUMO, ubiquitin, and proteasomes along chromosome axes was mediated largely by RNF212 (show RNF212 Proteins) and HEI10, two E3 ligases that are also essential for crossover recombination.
Antagonistic roles of ubiquitin ligase (show RNF123 Proteins) HEI10 and SUMO ligase RNF212 (show RNF212 Proteins) regulate meiotic recombination.
Mei4 and Rec114, are evolutionarily conserved in most eukaryotes and Mei4(-/-) mice are deficient in meiotic DSB formation, thus showing the functional conservation of Mei4 in mice
Cloning and characterization of the mei4 ortholog of Hei10 (also known as Gm288 in mouse) demonstrates a novel link between cell cycle regulation and mismatch repair during prophase I.
HEI10 defines a divergent class of E3 ubiquitin ligase (show MUL1 Proteins), functioning in progression through G(2)/M.
The cyclin B-binding protein and cell cycle regulator HEI10 is identified as a novel merlin (show NF2 Proteins)-binding partner; interaction with merlin (show NF2 Proteins) affects HEI10 protein levels.
HEI10 is a member of the E3 ubiquitin ligase family and functions in progression of the cell cycle through G(2)/M.
cyclin B1 interacting protein 1
, E3 ubiquitin-protein ligase CCNB1IP1
, human enhancer of invasion 10