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DRG2 encodes a GTP-binding protein known to function in the regulation of cell growth and differentiation. Additionally we are shipping DRG2 Kits (5) and DRG2 Proteins (4) and many more products for this protein.
Showing 10 out of 34 products:
Human Polyclonal DRG2 Primary Antibody for ICC, IF - ABIN4306292
Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells. in Nature methods 2013
Results show that the SNP (rs2257609 C>T) located in the intron region of SLC5A10 variant does not affect the expression of SLC5A10 mRNA, but alters the mRNA expression and promoter activity of DRG2. It is significantly associated with worse overall and disease-free survival of non-small-cell lung cancer (NSCLC) patients.
Taken together, our data demonstrate that DRG2 acts as a regulator of mitochondrial fission by controlling the expression of Drp1.
Authors observed that knockdown of DRG2 in HeLa cells affected growth in a wound-healing assay, and tumorigenicity in nude mice xenografts.
Results demonstrate that DRG2 is an endosomal protein and a key regulator of Rab5 deactivation and Tfn recycling.
miR19153p functions as a silencer of apoptosis, which regulates lung cancer apoptosis via targeting DRG2/PBX2.
Basal expression level of DRG2 is regulated by the Sp1 transcription factor.
overexpression of DRG2 in Jurkat cells affects genes regulating cell-cycle arrest and apoptosis, and that these molecular changes may be important in the growth or differentiation of cells
Our results reveal a novel mechanism for regulation of membrane tubule stability mediated by DRG2.
Developmentally regulated GTP-binding protein 2 ameliorates EAE by suppressing the development of TH17 cells.
DRG2 is associated with survival and cytoskeleton organization of osteoclasts under influence of macrophage colony-stimulating factor, and its overexpression leads to elevated bone resorptive activity of osteoclasts, resulting in bone loss.
This gene encodes a GTP-binding protein known to function in the regulation of cell growth and differentiation. Read-through transcripts containing this gene and a downstream gene have been identified, but they are not thought to encode a fusion protein. This gene is located within the Smith-Magenis syndrome region on chromosome 17.
developmentally-regulated GTP-binding protein 2
, developmentally regulated GTP binding protein 2
, developmentally regulated GTP-binding protein 2