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May constitute a novel regulatory system for basal transcription. Additionally we are shipping ESF1, Nucleolar Pre-RRNA Processing Protein, Homolog (S. Cerevisiae) Kits (6) and and many more products for this protein.
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our data indicate that SOX3 (show SOX3 Antibodies) may serve as an oncogene (show RAB1A Antibodies) in osteosarcoma
deletion of the SOX3 (show SOX3 Antibodies) gene may have a role in intellectual disability with hemophilia B
Results show that SOX3 (show SOX3 Antibodies) is upregulated in human osteosarcoma (OS) tissues and provide evidence that SOX3 (show SOX3 Antibodies) promotes migration, invasiveness, and EMT (show ITK Antibodies) in OS cells via transcriptional activation of Snail1 (show SNAI1 Antibodies) expression.
we provide a first map of the epigenetic landscape of SOX3 in pluripotent cells and during the early phases of neural differentiation. We found SOX3 gene to be non methylated from undifferentiated NT2/D1 to cells committed towards neural lineage.
These findings demonstrate the novel mechanism by which Sox3 contributes to endometrial cancer stem cell invasion and suggest that repression of Sox3 by microRNA-194 may have therapeutic potential to suppress endometrial carcinoma metastasis. The cancer stem cell marker, CD133, might be the surface marker of endometrial cancer stem cell.
Data indicate that SRY-box 3 transcription factor SOX-3 (show SOX3 Antibodies) targets Src kinase (show CSK Antibodies) in epithelial ovarian cancer (EOC) cells.
SOX3 (show SOX3 Antibodies) overdosage permits normal sex development in 46,XX individuals with random X inactivation.
Translocations interrupting this region may also affect the gonadal development, possibly depending on the chromatin context of the recipient chromosome. SOX3 (show SOX3 Antibodies) duplications may substitute SRY (show SRY Antibodies) in some XX subjects
Screening for SOX3 (show SOX3 Antibodies) should be advised not only for hypopituitary patients with an ectopic posterior pituitary, but also for those with a structurally normal pituitary
Our study provides additional evidence that deletion in polyalanine tracts of SOX3 (show SOX3 Antibodies) is associated with hypopituitarism
The Rattus rattus ABT1-associated protein formed a complex with ABT1 (show Abt1 Antibodies) and suppressed activation of Pol II (show 0 Antibodies)-directed transcription in mammalian cells. It binds and negatively regulates ABT1 (show Abt1 Antibodies).
This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. Mutations in this gene have been associated with X-linked mental retardation with growth hormone deficiency.
transcription factor SOX-3
, ABT1-associated protein
, ESF1 homolog