anti-Endoplasmic Reticulum To Nucleus Signaling 2 (ERN2) Antibodies

Induces translational repression through 28S ribosomal RNA cleavage in response to ER stress. Additionally we are shipping Endoplasmic Reticulum To Nucleus Signaling 2 Proteins (8) and Endoplasmic Reticulum To Nucleus Signaling 2 Kits (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ERN2 26918 Q9Z2E3
ERN2 10595 Q76MJ5
ERN2 365363  
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top anti-Endoplasmic Reticulum To Nucleus Signaling 2 Antibodies at antibodies-online.com

Showing 10 out of 55 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Goat Un-conjugated ELISA   100 μg Log in to see 6 to 7 Days
$291.53
Details
Human Rabbit Un-conjugated IF, IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using ERN2 Antibody. The picture on the right is treated with the synthesized peptide. Immunofluorescence analysis of A549 cells, using ERN2 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated WB The anti-ERN2 Pab (ABIN391195) is used in Western blot to detect ERN2 in mouse liver tissue lysate 400 μL Log in to see 10 to 11 Days
$385.00
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of ERN2 (arrow) in mouse stomach tissue lysates (35ug/lane) using ERN2 / IRE2  Antibody (N-term). 0.4 mL Log in to see 6 to 8 Days
$484.00
Details
Human Rabbit Un-conjugated WB Western blot analysis of ERN2 N-term (ABIN391194) in mouse stomach tissue lysates (35 µg/lane). ERN2 (arrow) was detected using the purified polyclonal antibody. 400 μL Log in to see 10 to 11 Days
$385.00
Details
Human Rabbit Un-conjugated EIA, WB The anti-ERN2 Pab is used in Western blot to detect ERN2 in mouse liver tissue lysate 0.4 mL Log in to see 6 to 8 Days
$484.00
Details
Human Rabbit Un-conjugated ELISA, IF, IHC, IHC (p) 100 μL Log in to see 11 to 14 Days
$493.17
Details
Mouse Rabbit Un-conjugated WB Western blot analysis in mouse testis tissue lysates (35ug/lane). 400 μL Log in to see 2 to 3 Days
$515.63
Details
Human Goat Un-conjugated ELISA   100 μg Log in to see 11 to 14 Days
$507.83
Details
Human Rabbit Un-conjugated IHC (p) Immunohistochemical staining of human kidney with ERN2 polyclonal antibody  shows granular cytoplasmic positivity in proximal tubules at 1:20-1:50 dilution. 100 μL Log in to see 11 to 12 Days
$577.33
Details

Top referenced anti-Endoplasmic Reticulum To Nucleus Signaling 2 Antibodies

  1. Human Polyclonal ERN2 Primary Antibody for ELISA - ABIN543637 : Wang, Harding, Zhang, Jolicoeur, Kuroda, Ron: Cloning of mammalian Ire1 reveals diversity in the ER stress responses. in The EMBO journal 1998 (PubMed)
    Show all 3 Pubmed References

  2. Human Polyclonal ERN2 Primary Antibody for ELISA - ABIN449712 : Brewer, Diehl: PERK mediates cell-cycle exit during the mammalian unfolded protein response. in Proceedings of the National Academy of Sciences of the United States of America 2000 (PubMed)

More Antibodies against Endoplasmic Reticulum To Nucleus Signaling 2 Interaction Partners

Mouse (Murine) Endoplasmic Reticulum To Nucleus Signaling 2 (ERN2) interaction partners

  1. Data show that LPS induces endoplasmic reticulum (ER) stress and P300 activity via the XBP1/IRE1 pathway.

  2. Regulated IRE1-dependent mRNA decay sets the threshold for dendritic cell survival.

  3. Data show that EIF2AK3/PERK-mediated downregulation of miR-424(322)-503 cluster regulates optimal activation of IRE1 protein and activating transcription factor 6 (ATF6) during conditions of endoplasmic reticulum stress.

  4. Our results reveal a role for IRE1 in preventing a cell death-initializing step that emanates from the ER and provide a potential target for treating diseases characterized by ER stress, including diabetes and Wolfram syndrome.

  5. Our data indicate that removal of XBP-1 confers a kinetic delay in early stages of MCMV infection and suggest that the late targeting of IRE1 is aimed at inhibiting activities other than the splicing of XBP-1 mRNA

  6. ER stress accentuated CVB3-induced myocardial inflammation through the IRE1-associated NF-kappaB pathway.

  7. This study provides the first in vivo evidence that PP2Ce is an essential regulator of normal lactation, possibly involving IRE1 signaling and endoplasmic reticulum stress regulation in mammary epithelium.

  8. suggest that activation of IRE1-JNK pathway is a key linker of impaired hepatic insulin signaling transduction induced by HFru feeding

  9. Regulated IRE1-dependent decay participates in curtailing immunoglobulin secretion from plasma cells.

  10. Regulated IRE1-dependent decay pathway is activated during Japanese encephalitis virus and benefits viral replication.

  11. required for airway epithelial mucin production

  12. findings suggest that in goblet cells, IRE1beta, but not IRE1alpha, promotes efficient protein folding and secretion in the ER by optimizing the level of mRNA encoding their major secretory product, MUC2

  13. Ire1beta regulates intestinal lipid absorption and that increased intestinal lipoprotein production contributes to atherosclerosis.

  14. Inhibition of IRE1 endonuclease activity does not sensitize cells to the consequences of acute endoplasmic reticulum stress, but rather interferes with the expansion of secretory capacity.

  15. early DENV-2 infection triggers and then suppresses PERK-mediated eIF2alpha phosphorylation and that in mid and late DENV-2 infection, the IRE1-XBP1 and ATF6 pathways are activated, respectively

  16. Transcriptional and posttranscriptional mechanisms involving NR2F1 and IRE1beta ensure low microsomal triglyceride transfer protein expression in undifferentiated intestinal cells and avoid apolipoprotein B lipoprotein biosynthesis.

  17. Endoplasmic reticulum stress blunts cytokine-triggered activation of NF-kappaB, in part through PERK- and IRE1-mediated preferential induction of C/EBPbeta.

  18. IRE1-mediated unconventional mRNA splicing is involved in regulating XBP1 in signaling the unfolded protein response.

  19. IRE1alpha, an ER-resident protein kinase, has a crucial function in insulin biosynthesis. IRE1alpha phosphorylation is coupled to insulin biosynthesis in response to transient exposure to high glucose.

  20. Mouse hepatitis virus infection activates the Ire1/XBP1 pathway of the unfolded protein response

Human Endoplasmic Reticulum To Nucleus Signaling 2 (ERN2) interaction partners

  1. ER stress-regulated IRE1 dependent decay is involved in regulation of hepatic diseases. (review)

  2. The luminal event mediated by IRE1beta involves direct interaction with unfolded proteins rather than association/dissociation with BiP.

  3. Data show that IRE1beta represses translation on the ER membrane but not in the cytosol, and that this selective repression depends on the RNase activity of IRE1beta.

  4. The structural, biochemical, and functional studies in vivo altogether demonstrate that IRE1 and PERK have conserved a common molecular interface necessary and sufficient for dimerization and unfolded protein response (UPR) signaling.

  5. RNase domain of IRE1 determines the functional specificities of each of these isoforms.

Endoplasmic Reticulum To Nucleus Signaling 2 (ERN2) Antigen Profile

Protein Summary

Induces translational repression through 28S ribosomal RNA cleavage in response to ER stress. Pro-apoptotic. Appears to play no role in the unfolded-protein response, unlike closely related proteins.

Gene names and symbols associated with ERN2

  • endoplasmic reticulum to nucleus signaling 2 (ERN2) antibody
  • endoplasmic reticulum to nucleus signaling 2 (ern2) antibody
  • endoplasmic reticulum (ER) to nucleus signalling 2 (Ern2) antibody
  • endoplasmic reticulum to nucleus signaling 2 (Ern2) antibody
  • Ern1 antibody
  • Ire1 antibody
  • IRE1-BETA antibody
  • IRE1b antibody
  • Ire1beta antibody

Protein level used designations for ERN2

endoplasmic reticulum to nucleus signaling 2 , endoplasmic reticulum to nucleus signalling 2 , endoplasmic reticulum (ER) to nucleus signalling 2 , endoplasmic reticulum-to-nucleus signaling 2 , inositol-requiring 1 (Yeast homologue) , inositol-requiring 1 beta , inositol-requiring protein 2 , ire1-beta , mIre1 , serine/threonine-protein kinase/endoribonuclease IRE2 , ER to nucleus signalling 2 , IRE1 beta , IRE1, S. cerevisiae, homolog of , hIRE2p

GENE ID SPECIES
453992 Pan troglodytes
779732 Xenopus (Silurana) tropicalis
26918 Mus musculus
10595 Homo sapiens
489970 Canis lupus familiaris
100624656 Sus scrofa
508486 Bos taurus
365363 Rattus norvegicus
Selected quality suppliers for anti-Endoplasmic Reticulum To Nucleus Signaling 2 (ERN2) Antibodies
Did you look for something else?