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The protein encoded by ELMO2 interacts with the dedicator of cyto-kinesis 1 protein. Additionally we are shipping ELMO2 Antibodies (66) and ELMO2 Kits (24) and many more products for this protein.
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These data suggest a novel link between Tiam1 and RhoG/ILK /ELMO2 pathway as upstream effectors of the Rac1-mediated phagocytic process in trabecular meshwork cells.
studies demonstrate that Elmo2 is a new regulator of insulin-dependent Glut4 membrane translocation through modulating Rac1 activity and Akt membrane compartmentalization.
findings highlight the necessity of ELMO2 for maintaining vascular integrity, specifically in intramembranous bones; loss-of-function mutations in ELMO2 cause intraosseous vascular malformation by impeding RAC1 signaling
Axl has a role in phosphorylating the Elmo scaffold proteins to promote Rac activation and cell invasion
uncovered a role for ELMO in the recruitment of ACF7 to the membrane to promote microtubule capture and stability
Through its association with ELMO2, ILK plays key roles in the regulation of Rho GTPases and cross-talk pathways between adhesion and growth factor receptors.
The protein encoded by this gene interacts with the dedicator of cyto-kinesis 1 protein. Similarity to a C. elegans protein suggests that this protein may function in phagocytosis of apoptotic cells and in cell migration. Alternative splicing results in multiple transcript variants encoding the same protein.
PH domain protein CED12A
, ced-12 homolog 2
, engulfment and cell motility protein 2
, protein ced-12 homolog A
, engulfment and cell motility 2
, engulfment and cell motility protein 2-like
, engulfment and cell motility 2, ced-12 homolog
, CED-12 homolog A