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EEF1G encodes a subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome.
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Human EEF1G Protein expressed in HEK-293 Cells - ABIN2719947
Li, Wei, Rawle, Qin, Wang, Soares, Jin, Sivakumaran, Lin, Spann, Abbott, Harrich: Specific Interaction between eEF1A and HIV RT Is Critical for HIV-1 Reverse Transcription and a Potential Anti-HIV Target. in PLoS pathogens 2015
Results show that eEF1Bgamma binds not only Che-1 and p53 transcripts but also their promoters. Its depletion significantly decreases p53 protein accumulation and slightly impacts on Che-1 accumulation in the mitochondria. These data support the notion that eEF1Bgamma, besides its canonical role in translation, is an RNA-binding protein and a key player in cellular stress responses.
eEF1gamma, in addition to its role in translation elongation complex, is involved in regulating Vimentin (show VIM Proteins) gene by contacting both pol II and the Vimentin (show VIM Proteins) promoter region and shuttling/nursing the Vimentin (show VIM Proteins) mRNA
This gene encodes a subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This subunit contains an N-terminal glutathione transferase domain, which may be involved in regulating the assembly of multisubunit complexes containing this elongation factor and aminoacyl-tRNA synthetases.
, eEF-1B gamma
, elongation factor 1-gamma
, pancreatic tumor-related protein
, translation elongation factor eEF-1 gamma chain
, elongation factor 1-gamma-like protein
, Elongation factor 1-gamma
, eukaryotic elongation factor 1 gamma-like protein
, nearly normal
, elongation factor 1 gamma
, eEF-1B gamma-A
, elongation factor 1-gamma-A
, elongation factor 1-gamma-B
, eEF-1B gamma-B
, elongation factor 1 gamma, EF-1 gamma
, eukaryotic translation elongation factor 1 gamma