Eukaryotic Translation Initiation Factor 5A2 Proteins (EIF5A2)

mRNA-binding protein involved in translation elongation. Additionally we are shipping EIF5A2 Antibodies (82) and EIF5A2 Kits (2) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
EIF5A2 56648 Q9GZV4
EIF5A2 208691 Q8BGY2
Rat EIF5A2 EIF5A2 310261  
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Top EIF5A2 Proteins at antibodies-online.com

Showing 10 out of 15 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$6,749.58
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$6,749.58
Details
Escherichia coli (E. coli) Human His tag   50 μg Log in to see 4 Days
$352.00
Details
Escherichia coli (E. coli) Human His tag 100 μg Log in to see 14 to 16 Days
$437.80
Details
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$414.29
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 11 Days
$814.00
Details
Yeast Orang-Utan His tag   1 mg Log in to see 60 to 71 Days
$2,337.50
Details
Yeast REACT_Tobacco His tag   1 mg Log in to see 60 to 71 Days
$2,357.67
Details
Yeast REACT_Alfalfa His tag   1 mg Log in to see 60 to 71 Days
$2,357.67
Details
Escherichia coli (E. coli) Human His tag   1 mg Log in to see 2 to 3 Days
$6,867.69
Details

EIF5A2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, ,
Mouse (Murine)

More Proteins for Eukaryotic Translation Initiation Factor 5A2 (EIF5A2) Interaction Partners

Human Eukaryotic Translation Initiation Factor 5A2 (EIF5A2) interaction partners

  1. EIF5A2 as a direct and functional target of miR-203.

  2. The model had 92% sensitivity and 92% specificity. We obtained similar results in the independent validation cohort. AIB1 and EIF5A2 show promise for the noninvasive detection of bladder cancer. The model based on AIB1, EIF5A2, and NMP22 outperformed each of the three individual biomarkers for detecting Bladder cancer.

  3. Data suggest that inhibition of eIF5A2 alters progression of the EMT to decrease the invasion and metastasis of HCC cells via ROS-related pathways.

  4. EIF5A2 overexpression may contribute to cancer progression and poor prognosis. Therefore, EIF5A2 could be a novel potential prognostic marker for Federation of Gynecology and Obstetrics (FIGO) stage I-II cervical cancer.

  5. High EIF5A2 expression is associated with hepatocellular carcinoma.

  6. MiR-30b suppresses tumor migration and invasion by targeting EIF5A2 expression in gastric cancer cells.

  7. eIF-5A2 plays an important role in doxorubicin chemoresistance in breast cancer cells.

  8. Data indicate that regulation of sonic hedgehog (SHh)-GLI family zinc finger 1 (Gli1) signals to migration of pancreatic cancer AsPC-1 Cells through mediating eukaryotic translation initiation factor 5A (EIF5A2) gene expression.

  9. Data suggest that eukaryotic translation initiation factor 5A2 (EIF5A2) inhibitors might be considered as combination therapy to enhance chemosensitivity in patients with esophageal squamous cell carcinoma (ESCC).

  10. Our findings indicate that EIF5A2 upregulation plays an important oncogenic role in gastric cancer. EIF5A2 may represent a new predictor for poor survival and is a potential therapeutic target for gastric cancer.

  11. Increased expression of eIF5A2 increases metastasis and angiogenesis in esophageal squamous cell carcinoma via the HIF1alpha-mediated signaling pathway.

  12. focus on updating current knowledge of the EIF5A2 gene in human cancers

  13. EIF5A2 elevated TGF-beta1 expression through STAT3 to induce epithelial-mesenchymal transition and promotes aggressiveness in bladder cancer.

  14. It significantly inhibited activity of eIF5A2.

  15. None of the latter died within 5 years in EIF5A2-negative staining group.

  16. eIF-5A as well as the hypusine-forming enzymes deoxyhypusine synthase (DHS) and deoxyhypusine hydroxylase (DOHH) are highly overexpressed in glioblastoma patient sample

  17. EIF5A2 promotes colorectal carcinoma cell aggressiveness by upregulating MTA1 through C-myc to induce epithelial-mesenchymaltransition.

  18. EIF5A2 plays an important role in hepatocellular carcinoma invasion and metastasis by inducing epithelial-mesenchymal transition, as well as stimulating cytoskeleton rearrangement through activation of RhoA and Rac1.

  19. role in eukaryotic cell survival similar to that of the ubiquitous eIF5A-1

  20. eIF-5A2 overexpression was significantly associated with the advanced stage of ovarian cancer.

Mouse (Murine) Eukaryotic Translation Initiation Factor 5A2 (EIF5A2) interaction partners

  1. activation of eIF-5A2 repressed p19 level and therefore destabilized p53 in transgenic mouse embryo fibroblast (MEF) cells. This subsequently allowed for the accumulation of chromosomal instability.

  2. Eukaryotic initiation factor 5A (eIF5A) (eIF-4D, eIF-5A) stimulates ribosomal peptidyltransferase activity, transport of HIV-1-mRNAs and binds exportins 1 and 4. Contains hypusine at lys 50. Mouse EIF5A1 and EIF5A2 encode two isoforms: eIF5AI and eIF5AII.

EIF5A2 Protein Profile

Protein Summary

mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation (By similarity).

Gene names and symbols associated with EIF5A2

  • eukaryotic translation initiation factor 5A2 (EIF5A2)
  • eukaryotic translation initiation factor 5A2 (eif5a2)
  • eukaryotic translation initiation factor 5A3 (LOC100499632)
  • eukaryotic translation initiation factor 5A2 (Eif5a2)
  • 9630038B20 protein
  • EIF-5A2 protein
  • EIF5A protein
  • EIF5A2 protein
  • eIF5AII protein
  • wu:fb05b06 protein
  • wu:fc23f04 protein
  • wu:fc61c10 protein
  • zgc:55504 protein
  • zgc:77429 protein

Protein level used designations for EIF5A2

eukaryotic translation initiation factor 5A-2 , eukaryotic translation initiation factor 5A2 , eukaryotic translation initiation factor 5A , eukaryotic translation initiation factor 5A3 , eIF-5A-2 , eukaryotic initiation factor 5A , eIF-5A2 , eIF-4D , initiation factor 5A

GENE ID SPECIES
506307 Bos taurus
488164 Canis lupus familiaris
406546 Danio rerio
744869 Pan troglodytes
100222130 Taeniopygia guttata
100499632 Glycine max
56648 Homo sapiens
208691 Mus musculus
310261 Rattus norvegicus
396545 Gallus gallus
100174570 Pongo abelii
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