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FEZ1 is an ortholog of the C. Additionally we are shipping FEZ1 Antibodies (58) and many more products for this protein.
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missense variant in the LZTS1 (show LZTS1 Proteins) gene was identified in two Ehlers-Danlos syndrome patients in an extended family.
LZTS1 (show LZTS1 Proteins) promoter was frequently methylated in IMPC samples.
Compared with the normal hepatocyte cells, LZTS1 (show LZTS1 Proteins) expression in hepatocellular carcinoma cells was significantly lower
miR (show MLXIP Proteins)-135b expression inversely correlated with LZTS1 (show LZTS1 Proteins) staining intensity and the Cutaneous Squamous Cell Carcinoma grade.
FEZ1 (show LZTS1 Proteins) promotes HIV-1 infection in non-neuronal cells via direct binding to the capsid and kinesin-1 to move the virus into the cell nucleus.
Suggest that LZTS1 (show LZTS1 Proteins) plays a potential tumor suppressor role in colorectal cancer progression and represents a valuable clinical prognostic marker of this disease.
Lzts1 (show LZTS1 Proteins) was significantly downregulated in breast cancer samples and its deregulation was associated with a higher incidence of tumor recurrence, and to a worse overall survival.
miR (show MLXIP Proteins)-214 functions as an onco-miRNA in osteosarcoma, and its oncogenic effects are mediated chiefly through downregulation of LZTS1 (show LZTS1 Proteins)
SCOC (show SCOC Proteins) forms a stable homogeneous complex with the coiled coil domain of FEZ1 (show LZTS1 Proteins). SCOC (show SCOC Proteins) dimerization and the SCOC (show SCOC Proteins) surface residue R117 are important for this interaction.
Studies indicate that FEZ1 (fasciculation and elongation protein zeta 1 (show LZTS1 Proteins)), SCOCO (short coiled-coil protein (show SCOC Proteins)) and kinesins (kinesin heavy chain (show KIF5A Proteins)) are involved in biological transport process.
Phosphorylation of FEZ1 by MARK regulates its function in presynaptic protein trafficking.
Dendrite growth depends on degradation of FEZ1 regulated by Cdc20 (show CDC20 Proteins)/APC (show APC Proteins).
Fezzeta-1 interacts with disrupted in schizophrenia (DISC)1 (show DISC1 Proteins) to synergistically regulate dendritic growth of newborn neurons in the adult mouse hippocampus.
Fez1 is mainly expressed in cortical layers V and VI, not in gamma-aminobutyric acid neurons but in pyramidal neurons, the projection neurons of the cerebral cortex. Immunohistochemistry also shows that Fez1 is expressed in deep layers of the neocortex.
investigated the role of FEZ1 in brain development and the pathogenesis of schizophrenia by generating mice that lack Fez1
fez1 (show LZTS1 Proteins) is crucial for establishing regional subdivisions within the diencephalon and may also play a role in the development of the telencephalon and hypothalamus.
This gene is an ortholog of the C. elegans unc-76 gene, which is necessary for normal axonal bundling and elongation within axon bundles. Expression of this gene in C. elegans unc-76 mutants can restore to the mutants partial locomotion and axonal fasciculation, suggesting that it also functions in axonal outgrowth. The N-terminal half of the gene product is highly acidic. Alternatively spliced transcript variants encoding different isoforms of this protein have been described.
F37/Esophageal cancer-related gene-coding leucine-zipper motif
, leucine zipper putative tumor suppressor 1
, fasciculation and elongation protein zeta-1
, zygin I
, protein kinase C-binding protein Zeta1
, zygin 1
, fasciculation and elongation protein zeta 1 (zygin I)
, fasciculation and elongation protein zeta 1 L homeolog