anti-Forkhead Box C2 (MFH-1, Mesenchyme Forkhead 1) (FOXC2) Antibodies

FOXC2 belongs to the forkhead family of transcription factors which is characterized by a distinct DNA-binding forkhead domain. Additionally we are shipping FOXC2 Kits (28) and FOXC2 Proteins (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
FOXC2 14234 Q61850
FOXC2 171356  
FOXC2 2303 Q99958
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Top anti-FOXC2 Antibodies at antibodies-online.com

Showing 10 out of 113 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-Foxc2 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  Mouse Uterus 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Goat Un-conjugated ELISA, ICC, IF, IHC, IHC (fro), IHC (p), WB Western Blot: FOX C2 Antibody [ABIN249942] - ABIN249942 staining (1ug/ml) of Human Breast Cancer lysate (RIPA buffer, 30ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. Western Blot: FoxC2 Antibody [ABIN249942] - HEK293 lysate (10ug protein in RIPA buffer) over expressing Human FOXC2 with DYKDDDDK tag probed with FoxC2 (0.1ug/ml) in Lane A and probed with anti- DYKDDDDK Tag (1/1000) in lane C. Mock-transfected HEK293 probed with FoxC2 (1mg/ml) in Lane B. Prima 0.1 mg Log in to see 7 to 9 Days
$485.88
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-FOXC2 Antibody Titration:  1.25ug/ml  Positive Control:  Human Kidney 100 μL Log in to see 2 to 3 Days
$229.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-FOXC2 Antibody Titration: 1.25ug/ml ELISA Titer: 1:1562500 Positive Control: Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Goat Un-conjugated IHC, ELISA, WB ABIN185029 staining (1µg/ml) of Human Breast Cancer lysate (RIPA buffer, 30µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. HEK293 lysate (10 µg protein in RIPA buffer) over expressing Human FOXC2 with DYKDDDDK tag probed with ABIN185029 (0.1 µg/mL) in Lane A and probed with anti- DYKDDDDK Tag (1/1000) in lane C. Mock-transfected HEK293 probed with ABIN185029 (1mg/ml) in Lane B. Primary incubations were for 1 hour. Detected by chemiluminescence. 100 μg Log in to see 6 to 7 Days
$358.02
Details
Human Mouse Un-conjugated ELISA, IF, IHC, WB Immunofluorescence of monoclonal antibody to FOXC2 on HeLa cell (antibody concentration 10 µg/mL). FOXC2 monoclonal antibody (M02), clone 2H3 Western Blot analysis of FOXC2 expression in PC-12. 100 μg Log in to see 8 to 11 Days
$461.00
Details
Human Rabbit Un-conjugated FACS, WB FOXC2 Antibody (Center P198) (ABIN655526) flow cytometric analysis of HL-60 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. 400 μL Log in to see 10 to 11 Days
$335.50
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB FOXC2 Antibody (Center S174) (ABIN651936) western blot analysis in A2058 cell line lysates (15 µg/lane). This demonstrates the FOXC2 antibody detected the FOXC2 protein (arrow). FOXC2 Antibody (Center S174) (ABIN651936) immunohistochemistry analysis in formalin fixed and paraffin embedded human cervix carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Log in to see 10 to 11 Days
$335.50
Details
Human Mouse Un-conjugated IF, IHC (p), ELISA, WB Immunoperoxidase of monoclonal antibody to FOXC2 on formalin-fixed paraffin-embedded human lateral ventricle wall. [antibody concentration 3 ug/ml] Immunofluorescence of monoclonal antibody to FOXC2 on HeLa cell. [antibody concentration 10 ug/ml] 100 μg Log in to see 11 to 12 Days
$440.00
Details

Top referenced anti-FOXC2 Antibodies

  1. Human Polyclonal FOXC2 Primary Antibody for ELISA, ICC - ABIN249942 : Zarbalis, Siegenthaler, Choe, May, Peterson, Pleasure: Cortical dysplasia and skull defects in mice with a Foxc1 allele reveal the role of meningeal differentiation in regulating cortical development. in Proceedings of the National Academy of Sciences of the United States of America 2007 (PubMed)
    Show all 4 Pubmed References

  2. Human Monoclonal FOXC2 Primary Antibody for IF, IHC (p) - ABIN560913 : Nishida, Mimori, Yokobori, Sudo, Tanaka, Shibata, Ishii, Doki, Mori: FOXC2 is a novel prognostic factor in human esophageal squamous cell carcinoma. in Annals of surgical oncology 2011 (PubMed)
    Show all 3 Pubmed References

  3. Cow (Bovine) Polyclonal FOXC2 Primary Antibody for WB - ABIN610743 : Henis-Korenblit, Strumpf, Goldstaub, Kimchi: A novel form of DAP5 protein accumulates in apoptotic cells as a result of caspase cleavage and internal ribosome entry site-mediated translation. in Molecular and cellular biology 2000 (PubMed)
    Show all 2 Pubmed References

  4. Human Monoclonal FOXC2 Primary Antibody for ELISA, WB - ABIN1724771 : Jiang, Pang, Wang, Shen, Chen, Xi: Prognostic role of Twist, Slug, and Foxc2 expression in stage I non-small-cell lung cancer after curative resection. in Clinical lung cancer 2012 (PubMed)
    Show all 2 Pubmed References

  5. Human Monoclonal FOXC2 Primary Antibody for ELISA, WB - ABIN1724772 : Watanabe, Kobunai, Yamamoto, Matsuda, Ishihara, Nozawa, Iinuma, Kanazawa, Tanaka, Konishi, Ikeuchi, Eshima, Muto, Nagawa: Gene expression of mesenchyme forkhead 1 (FOXC2) significantly correlates with the degree of lymph node metastasis in colorectal cancer. in International surgery 2012 (PubMed)
    Show all 2 Pubmed References

More Antibodies against FOXC2 Interaction Partners

Mouse (Murine) Forkhead Box C2 (MFH-1, Mesenchyme Forkhead 1) (FOXC2) interaction partners

  1. Foxc2 influences alveolar epithelial cell differentiation during lung development

  2. Study shows that alpha melanocyte stimulating hormone (show POMC Antibodies) and forkhead box C2 protein promote fatty acid oxidation through C/EBPbeta (show CEBPB Antibodies) negative transcription in mice adipose tissue.

  3. FOXC1 (show FOXC1 Antibodies) and FOXC2 are essential regulators of lymphangiogenesis and may have roles in lymphatic-associated diseases

  4. Compound, NC-specific Foxc1 (show FOXC1 Antibodies); Foxc2 homozygous mutant mice have more severe defects in structures of the ocular surface, such as the cornea and eyelids, accompanied by significant declines in the expression of another key developmental factor, Pitx2 (show PITX2 Antibodies), and its downstream effector Dkk2 (show DKK2 Antibodies), which antagonizes canonical Wnt (show WNT2 Antibodies) signaling.

  5. Foxc1 (show FOXC1 Antibodies) and Foxc2 maintain glomerular podocyte integrity by regulating the gene expression. Foxc2 plays a more critical role than Foxc1 (show FOXC1 Antibodies).

  6. Foxc1 (show FOXC1 Antibodies) and Foxc2 have a role in kidney and axial skeleton development.

  7. Our results are consistent with previous reports of Foxc2 expression during early embryogenesis and the Foxc2(CreERT2) mouse provides a tool to investigate spatiotemporal roles of Foxc2 and contributions of Foxc2(+) expressing cells during mouse embryogenesis.

  8. Conditional knockout of Foxc2 gene in kidney has been generated using conditional alleles of single-exon gene by double-selection system.

  9. Data show that segregation of Foxc2 and NFATc1 (show NFATC1 Antibodies) transcription factor is closely associated with the highly polarized expression of connexins Cx37 (show GJA4 Antibodies), Cx43 (show GJA1 Antibodies), and Cx47 (show GJC2 Antibodies).

  10. deletion of Foxc1 (show FOXC1 Antibodies) and Foxc2 specifically in Pax3 (show PAX3 Antibodies)-positive cells affects cell fate choices in the dermomyotome of somites at forelimb level, promoting the myogenic cell fate at the expense of endothelial cells that migrate to the limb

Human Forkhead Box C2 (MFH-1, Mesenchyme Forkhead 1) (FOXC2) interaction partners

  1. REVIEW: current understanding of FOXC2 and provide potential mechanistic explanations of the relationship between FOXC2 and cancer, as well as discuss the prospect for future research in the promising prognostic value of FOXC2 in cancer

  2. The finding of rare LAMA5 (show LAMA5 Antibodies) variants together with FOXC2 mutations in lymphedema-distichiasis syndrome suggests that these mutations may be co-responsible for these disorders and most likely interfere with the function of lymphatics.

  3. In FOXC2 knockdown cell lines, CXCR4 (show CXCR4 Antibodies), a downstream target of FOXC2, can restore osteosarcoma cell invasiveness and metastasis to the lung

  4. Knockdown of FOXC2 inhibited HCC (show FAM126A Antibodies) cell growth, migration, and invasion in vitro, as well as tumor growth.

  5. Studied interactions between protein kinase C alpha (PKCalpha (show PKCa Antibodies)), FOXC2, and p120-catenin (CTNND1 (show CTNND1 Antibodies)) in breast cancer, cell migration/ invasion; found PKCalpha (show PKCa Antibodies) acts as an upstream regulator of FOXC2, which in turn represses the expression of p120-catenin (show CTNND1 Antibodies), in both in endocrine resistant ER+breast cancer and basal A triple negative breast cancer.

  6. FOXC2 and CLIP4 activity correlates to the presence of

  7. either a complete loss or a significant gain of FOXC2 function can cause a perturbation of lymphatic vessel formation leading to lymphedema.

  8. Association of polymorphisms near the FOXC2 gene with the risk of varicose veins in ethnic Russians.

  9. respectively. Foxc2 is expressed in the developing kidney and therefore congenital renal anomalies may well be associated, potentially as a low penetrance feature. We propose that all individuals diagnosed with Lymphedema distichiasis syndrome should have a baseline renal ultrasound scan at diagnosis

  10. Genomic analysis of blood and excised valve tissue showed down-regulation of FOXC1 (show FOXC1 Antibodies) but also FOXC2 expression in the diseased aortic valve. This allows us to speculate on the potential role of FOXC1 (show FOXC1 Antibodies) in aortic valve anomalies.

FOXC2 Antigen Profile

Protein Summary

This gene belongs to the forkhead family of transcription factors which is characterized by a distinct DNA-binding forkhead domain. The specific function of this gene has not yet been determined\; however, it may play a role in the development of mesenchymal tissues.

Gene names and symbols associated with FOXC2

  • forkhead box C2 (FOXC2) antibody
  • forkhead box C2 (Foxc2) antibody
  • forkhead box C2 (MFH-1, mesenchyme forkhead 1) (FOXC2) antibody
  • Fkh14 antibody
  • FKHL14 antibody
  • FOXC2 antibody
  • Hfhbf3 antibody
  • LD antibody
  • MFH-1 antibody
  • MFH1 antibody

Protein level used designations for FOXC2

forkhead box C2 (MFH-1, mesenchyme forkhead 1) , forkhead box C2 , forkhead box protein C2 , forkhead box protein C2-like , BF-3 , brain factor 3 , forkhead homolog 14 , forkhead-related protein FKHL14 , mesenchyme fork head protein 1 , transcription factor FKH-14 , HFH-BF-3 , forkhead box C2 (MFH-1 mesenchyme forkhead 1) , winged helix transcriptional factor MFH-1 , MFH-1,mesenchyme forkhead 1 , forkhead, Drosophila, homolog-like 14

GENE ID SPECIES
468058 Pan troglodytes
694852 Macaca mulatta
100036555 Equus caballus
100407050 Callithrix jacchus
14234 Mus musculus
171356 Rattus norvegicus
396039 Gallus gallus
2303 Homo sapiens
489671 Canis lupus familiaris
507300 Bos taurus
101103500 Ovis aries
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