Golgi Reassembly Stacking Protein 2, 55kDa Proteins (GORASP2)

GORASP2 encodes a member of the Golgi reassembly stacking protein family. Additionally we are shipping Golgi Reassembly Stacking Protein 2, 55kDa Antibodies (97) and and many more products for this protein.

list all proteins Gene Name GeneID UniProt
GORASP2 70231 Q99JX3
GORASP2 113961  
GORASP2 26003 Q9H8Y8
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Top Golgi Reassembly Stacking Protein 2, 55kDa Proteins at antibodies-online.com

Showing 7 out of 9 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$9,797.11
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Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$9,797.11
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Escherichia coli (E. coli) Human His tag 100 μg Log in to see 13 to 16 Days
$400.00
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Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$414.29
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Escherichia coli (E. coli) Human His tag Validation with Western Blot 50 μg Log in to see Available
$284.90
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Yeast Rat His tag   1 mg Log in to see 60 to 71 Days
$3,272.50
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Escherichia coli (E. coli) Human GST tag   10 μg Log in to see 2 to 3 Days
$723.08
Details

GORASP2 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Rat (Rattus)

Human , ,
,

More Proteins for Golgi Reassembly Stacking Protein 2, 55kDa (GORASP2) Interaction Partners

Mouse (Murine) Golgi Reassembly Stacking Protein 2, 55kDa (GORASP2) interaction partners

  1. GOLPH2 (show GOLM1 Proteins) promotes the progression of pancreatic ductal adenocarcinoma.

  2. Gorasp2-/- mice suffered from spermatogenesis defects. Golgi morphology of spermatocytes was disturbed in Gorasp2-/- mice. GRASP55 interacted via PDZ-mediated interactions with JAMs.

  3. GRASP55 responds to inflammasome stimulation,controls autophagy initiation and important for secretion of IL-1b (show IL1B Proteins) and IL-18 (show IL18 Proteins)

Human Golgi Reassembly Stacking Protein 2, 55kDa (GORASP2) interaction partners

  1. Results demonstrate a critical role for GRASP55 and GRASP65 (show GORASP1 Proteins) in maintaining the stacked structure of the Golgi, which is required for accurate posttranslational modifications in the Golgi. Additionally, the GRASP knockout cell lines developed in this study will be useful tools for studying the role of GRASP proteins in other important cellular processes.

  2. binding site at the cleft between the PDZ1 and PDZ2 domains of GRASP65 (show GORASP1 Proteins) is dominated by hydrophobic interactions with GM130 (show GOLGA2 Proteins) that are not observed in the GRASP55-Golgin45 (show BLZF1 Proteins) complex

  3. GRASP55 interacts with CD83 (show CD83 Proteins) shortly after induction of dendritic cells maturation.

  4. Cisternal-specific functions of GRASP65 (show GORASP1 Proteins) and GRASP55 in continuity, compartmentalization, and function of the Golgi ribbon.

  5. propose that GRASP55/65 are negative regulators of exocytic transport and that this slowdown helps to ensure more complete protein glycosylation in the Golgi stack and proper sorting at the trans-Golgi network

  6. GRASP55 may function as an adaptor protein coupling MT1-MMP (show MMP14 Proteins) with furin (show FURIN Proteins), thus leading to the activation of the zymogen.

  7. These results demonstrate that GRASP55 and GRASP65 (show GORASP1 Proteins) stack mammalian Golgi cisternae via a common mechanism.

  8. Data demonstrate that both GRASP55 and 65 are needed for the efficient transport to and through the Golgi complex, thus highlighting a novel role for the GRASPs in membrane trafficking.

  9. GRASP65 (show GORASP1 Proteins) is an important structural component required for maintenance of Golgi apparatus integrity

  10. MEK1 (show MAP2K1 Proteins)/ERK (show EPHB2 Proteins) regulation of GRASP55-mediated Golgi linking is a control point in cell cycle progression

Golgi Reassembly Stacking Protein 2, 55kDa (GORASP2) Protein Profile

Protein Summary

This gene encodes a member of the Golgi reassembly stacking protein family. These proteins may play a role in the stacking of Golgi cisternae and Golgi ribbon formation, as well as Golgi fragmentation during apoptosis or mitosis. The encoded protein also plays a role in the intracellular transport of transforming growth factor alpha and may function as a molecular chaperone. A pseudogene of this gene is located on the short arm of chromosome 2. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene names and symbols associated with GORASP2

  • golgi reassembly stacking protein 2 L homeolog (gorasp2.L)
  • golgi reassembly stacking protein 2 (gorasp2)
  • golgi reassembly stacking protein 2 (GORASP2)
  • golgi reassembly stacking protein 2 (CC1G_02936)
  • golgi reassembly stacking protein 2 (Gorasp2)
  • 0610011A07Rik protein
  • 2410043M02Rik protein
  • 5730520M13Rik protein
  • 9430094F20Rik protein
  • AW552058 protein
  • DKFZp459O1715 protein
  • GOLPH2 protein
  • GOLPH6 protein
  • GRASP55 protein
  • Grs2 protein
  • MGC53281 protein
  • MGC73072 protein
  • MGC132131 protein
  • p59 protein
  • zgc:73072 protein

Protein level used designations for GORASP2

golgi reassembly stacking protein 2, 55kDa , Golgi reassembly-stacking protein 2 , golgi reassembly stacking protein 2 , golgi reassembly-stacking protein of 55 kDa , golgi phosphoprotein 6

GENE ID SPECIES
380211 Xenopus laevis
393676 Danio rerio
424156 Gallus gallus
488395 Canis lupus familiaris
513771 Bos taurus
6012383 Coprinopsis cinerea okayama7130
100173865 Pongo abelii
70231 Mus musculus
113961 Rattus norvegicus
26003 Homo sapiens
101926731 Macaca fascicularis
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