Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
GADD45GIP1 encodes a nuclear-localized protein that may be induced by p53 and regulates the cell cycle by inhibiting G1 to S phase progression. Additionally we are shipping Growth Arrest and DNA-Damage-Inducible, gamma Interacting Protein 1 Antibodies (37) and and many more products for this protein.
Showing 7 out of 7 products:
NRF2 (show GABPA Proteins) Ser40 phosphorylation was inhibited in Crif1-deficient bone marrow multipotent mesenchymal stromal cells even in the presence of three kinds of PKC (show PRRT2 Proteins) agonists, suggesting that CRIF1 might co-activate PKC-delta (show PKCd Proteins) to phosphorylate NRF2 (show GABPA Proteins) Ser40.
strongly suggest that CRIF1 deficiency promotes endothelial cell inflammation by increasing VCAM-1 (show VCAM1 Proteins) expression, elevating inflammatory cytokines levels, and activating the transcription factor NF-kappaB (show NFKB1 Proteins), all of which were inhibited by SIRT1 (show SIRT1 Proteins) overexpression
Results demonstrate that knockdown of CRIF1 in HUVECs induces mitochondrial dysfunction and reduces SIRT1 (show SIRT1 Proteins) expression along with decreased eNOS (show NOS3 Proteins) phosphorylation and increased eNOS (show NOS3 Proteins) acetylation, thereby promoting endothelial dysfunction. These findings indicate that CRIF1 plays an important role in maintaining mitochondrial and endothelial function through its effects on the SIRT1 (show SIRT1 Proteins)-eNOS (show NOS3 Proteins) pathway.
SNF5 (show SMARCB1 Proteins) is indispensable for CRIF1-enhanced p53 (show TP53 Proteins) activity and its function in the suppression of cell cycle arrest in human cancer cells.
Study shows that Lck (show LCK Proteins) interacts with CRIF1 in the mitochondria and negatively regulates CRIF1-mediated translation of mitochondrion-encoded proteins.
our results support a novel function of nuclear Lck (show LCK Proteins) in promoting human leukemic T cell survival through interaction with a tumor suppressor, CRIF1
Crif1 is an indispensable regulator of PKAalpha cat that modulates the PKA/CREB (show CREB1 Proteins) signaling pathway to promote adipogenic differentiation of bone marrow mesenchymal stem cells after irradiation
The results identify the ROS (show ROS1 Proteins)-Sp1 (show PSG1 Proteins)-Crif1 pathway to be a new mechanism underlying Abeta (show APP Proteins)-induced mitochondrial dysfunction and suggest that ROS (show ROS1 Proteins)-mediated downregulation of Crif1 is a crucial event in AD pathology.
CRIF1 knockdown partially induces endothelial activation via increased ROS (show ROS1 Proteins) production and phosphorylation of p66shc (show SHC1 Proteins)
CRIF1 may play a regulatory role in the BM microenvironment-induced leukemia cell cycle arrest possibly through interacting with CDK2 (show CDK2 Proteins) and acting as a cyclin-dependent kinase (show CDK1 Proteins) inhibitor.
Crif1(beta-/-) mouse is a useful model for the study of beta cell failure caused by mitochondrial OxPhos dysfunction.
The results identify the ROS (show ROS1 Proteins)-Sp1 (show SP1 Proteins)-Crif1 pathway to be a new mechanism underlying Abeta (show APP Proteins)-induced mitochondrial dysfunction and suggest that ROS (show ROS1 Proteins)-mediated downregulation of Crif1 is a crucial event in AD pathology.
Study showed that loss of Crif1 impairs mitochondrial oxidative phosphorylation and adipocyte differentiation in vitro and in vivo.
Crif1 plays a critical role in the maintenance of both mitochondrial structure and respiration in cardiac muscles.
Although adipose-specific Crif1-haploinsufficient mice showed normal growth and development, they became insulin (show INS Proteins)-resistant.
CRIF1 is essential for the synthesis and insertion of oxidative phosphorylation polypeptides in the mammalian mitochondrial membrane.
Results reveal that Crif1 is a novel and essential transcriptional coactivator of Elf3 (show EFNB3 Proteins) for the terminal differentiation of absorptive enterocytes.
Crif1 is a novel and essential transcriptional coactivator of STAT3 (show STAT3 Proteins) that modulates its DNA binding ability.
This gene encodes a nuclear-localized protein that may be induced by p53 and regulates the cell cycle by inhibiting G1 to S phase progression. The encoded protein may interact with other cell cycle regulators.
CKII beta binding protein 2
, CKII beta-associating protein
, CR6 interacting factor 1
, growth arrest and DNA damage-inducible proteins-interacting protein 1
, growth arrest- and DNA damage-inducible GADD45G-interacting protein
, p53-responsive gene 6 protein
, papillomavirus L2 interacting nuclear protein 1
, growth arrest and DNA-damage-inducible proteins-interacting protein 1