Growth Arrest and DNA-Damage-Inducible, gamma Interacting Protein 1 Proteins (GADD45GIP1)

GADD45GIP1 encodes a nuclear-localized protein that may be induced by p53 and regulates the cell cycle by inhibiting G1 to S phase progression. Additionally we are shipping Growth Arrest and DNA-Damage-Inducible, gamma Interacting Protein 1 Antibodies (37) and and many more products for this protein.

list all proteins Gene Name GeneID UniProt
GADD45GIP1 90480 Q8TAE8
GADD45GIP1 102060 Q9CR59
Rat GADD45GIP1 GADD45GIP1 288916 Q5XJW2
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Top Growth Arrest and DNA-Damage-Inducible, gamma Interacting Protein 1 Proteins at antibodies-online.com

Showing 7 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$5,465.26
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$6,869.04
Details
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$414.29
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see Available
$814.00
Details
Escherichia coli (E. coli) Human His tag 50 μg Log in to see 15 to 19 Days
$492.31
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Yeast Cow His tag   1 mg Log in to see 60 to 71 Days
$2,553.83
Details
Yeast REACT_Green monkey His tag   1 mg Log in to see 60 to 71 Days
$2,553.83
Details

GADD45GIP1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine)

More Proteins for Growth Arrest and DNA-Damage-Inducible, gamma Interacting Protein 1 (GADD45GIP1) Interaction Partners

Human Growth Arrest and DNA-Damage-Inducible, gamma Interacting Protein 1 (GADD45GIP1) interaction partners

  1. NRF2 (show GABPA Proteins) Ser40 phosphorylation was inhibited in Crif1-deficient bone marrow multipotent mesenchymal stromal cells even in the presence of three kinds of PKC (show PRRT2 Proteins) agonists, suggesting that CRIF1 might co-activate PKC-delta (show PKCd Proteins) to phosphorylate NRF2 (show GABPA Proteins) Ser40.

  2. strongly suggest that CRIF1 deficiency promotes endothelial cell inflammation by increasing VCAM-1 (show VCAM1 Proteins) expression, elevating inflammatory cytokines levels, and activating the transcription factor NF-kappaB (show NFKB1 Proteins), all of which were inhibited by SIRT1 (show SIRT1 Proteins) overexpression

  3. Results demonstrate that knockdown of CRIF1 in HUVECs induces mitochondrial dysfunction and reduces SIRT1 (show SIRT1 Proteins) expression along with decreased eNOS (show NOS3 Proteins) phosphorylation and increased eNOS (show NOS3 Proteins) acetylation, thereby promoting endothelial dysfunction. These findings indicate that CRIF1 plays an important role in maintaining mitochondrial and endothelial function through its effects on the SIRT1 (show SIRT1 Proteins)-eNOS (show NOS3 Proteins) pathway.

  4. SNF5 (show SMARCB1 Proteins) is indispensable for CRIF1-enhanced p53 (show TP53 Proteins) activity and its function in the suppression of cell cycle arrest in human cancer cells.

  5. Study shows that Lck (show LCK Proteins) interacts with CRIF1 in the mitochondria and negatively regulates CRIF1-mediated translation of mitochondrion-encoded proteins.

  6. our results support a novel function of nuclear Lck (show LCK Proteins) in promoting human leukemic T cell survival through interaction with a tumor suppressor, CRIF1

  7. Crif1 is an indispensable regulator of PKAalpha cat that modulates the PKA/CREB (show CREB1 Proteins) signaling pathway to promote adipogenic differentiation of bone marrow mesenchymal stem cells after irradiation

  8. The results identify the ROS (show ROS1 Proteins)-Sp1 (show PSG1 Proteins)-Crif1 pathway to be a new mechanism underlying Abeta (show APP Proteins)-induced mitochondrial dysfunction and suggest that ROS (show ROS1 Proteins)-mediated downregulation of Crif1 is a crucial event in AD pathology.

  9. CRIF1 knockdown partially induces endothelial activation via increased ROS (show ROS1 Proteins) production and phosphorylation of p66shc (show SHC1 Proteins)

  10. CRIF1 may play a regulatory role in the BM microenvironment-induced leukemia cell cycle arrest possibly through interacting with CDK2 (show CDK2 Proteins) and acting as a cyclin-dependent kinase (show CDK1 Proteins) inhibitor.

Mouse (Murine) Growth Arrest and DNA-Damage-Inducible, gamma Interacting Protein 1 (GADD45GIP1) interaction partners

  1. Crif1(beta-/-) mouse is a useful model for the study of beta cell failure caused by mitochondrial OxPhos dysfunction.

  2. The results identify the ROS (show ROS1 Proteins)-Sp1 (show SP1 Proteins)-Crif1 pathway to be a new mechanism underlying Abeta (show APP Proteins)-induced mitochondrial dysfunction and suggest that ROS (show ROS1 Proteins)-mediated downregulation of Crif1 is a crucial event in AD pathology.

  3. CRIF1 knockdown partially induces endothelial activation via increased ROS (show ROS1 Proteins) production and phosphorylation of p66shc (show SHC1 Proteins)

  4. Study showed that loss of Crif1 impairs mitochondrial oxidative phosphorylation and adipocyte differentiation in vitro and in vivo.

  5. Crif1 plays a critical role in the maintenance of both mitochondrial structure and respiration in cardiac muscles.

  6. Although adipose-specific Crif1-haploinsufficient mice showed normal growth and development, they became insulin (show INS Proteins)-resistant.

  7. CRIF1 is essential for the synthesis and insertion of oxidative phosphorylation polypeptides in the mammalian mitochondrial membrane.

  8. Results reveal that Crif1 is a novel and essential transcriptional coactivator of Elf3 (show EFNB3 Proteins) for the terminal differentiation of absorptive enterocytes.

  9. Crif1 is a novel and essential transcriptional coactivator of STAT3 (show STAT3 Proteins) that modulates its DNA binding ability.

Growth Arrest and DNA-Damage-Inducible, gamma Interacting Protein 1 (GADD45GIP1) Protein Profile

Protein Summary

This gene encodes a nuclear-localized protein that may be induced by p53 and regulates the cell cycle by inhibiting G1 to S phase progression. The encoded protein may interact with other cell cycle regulators.

Gene names and symbols associated with GADD45GIP1

  • growth arrest and DNA-damage-inducible, gamma interacting protein 1 (gadd45gip1)
  • GADD45G interacting protein 1 (GADD45GIP1)
  • growth arrest and DNA-damage-inducible, gamma interacting protein 1 (Gadd45gip1)
  • GADD45G interacting protein 1 (Gadd45gip1)
  • 2310040G17Rik protein
  • AI425883 protein
  • CKBBP2 protein
  • Crif1 protein
  • PLINP protein
  • PLINP-1 protein
  • Plinp1 protein
  • PRG6 protein
  • si:dkey-194e13.6 protein

Protein level used designations for GADD45GIP1

CKII beta binding protein 2 , CKII beta-associating protein , CR6 interacting factor 1 , growth arrest and DNA damage-inducible proteins-interacting protein 1 , growth arrest- and DNA damage-inducible GADD45G-interacting protein , p53-responsive gene 6 protein , papillomavirus L2 interacting nuclear protein 1 , growth arrest and DNA-damage-inducible proteins-interacting protein 1

GENE ID SPECIES
402803 Danio rerio
90480 Homo sapiens
102060 Mus musculus
288916 Rattus norvegicus
504718 Bos taurus
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