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Guanylate-binding proteins, such as GBP4, are induced by interferon and hydrolyze GTP to both GDP and GMP (Vestal, 2005 [PubMed 16108726]).[supplied by OMIM, Dec 2008].. Additionally we are shipping GBP4 Antibodies (56) and GBP4 Kits (25) and many more products for this protein.
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GBP4 is a negative regulator of virus-triggered type I interferon (IFN-I) production, interacting as a novel protein targeting interferon regulatory factor (IRF)-7 and inhibiting its function.
Two splice variants of mGBP4 could be detected. One variant led to a premature stop codon after 312 bp. The second variant resulted in a transcript with a disrupted G2 domain.
GBP4 is a positional candidate determining adult cattle stature.
Gbp4 is required for the inflammasome-dependent clearance of Salmonella Typhimurium (ST) by neutrophils in vivo.
Guanylate-binding proteins, such as GBP4, are induced by interferon and hydrolyze GTP to both GDP and GMP (Vestal, 2005
guanylate nucleotide binding protein 4
, guanylate-binding protein 4 homolog
, macrophage activation 2
, GTP-binding protein 4
, guanine nucleotide-binding protein 4
, guanylate-binding protein 4
, guanylate nucleotide binding protein 3
, guanylate binding protein 4
, guanylate-binding protein 4-like
, LOW QUALITY PROTEIN: guanylate-binding protein 4
, guanylate binding protein 3
, guanylate binding protein 4 L homeolog
, guanylate binding protein 4 S homeolog