Hemoglobin, gamma G Proteins (HBG2)

The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Additionally we are shipping HBG2 Kits (31) and HBG2 Antibodies (25) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
HBG2 3048 P69892
HBG2    
HBG2    
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Top HBG2 Proteins at antibodies-online.com

Showing 7 out of 9 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$5,465.26
Details
Escherichia coli (E. coli) Human His tag 100 μg Log in to see 15 to 19 Days
$400.00
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see Available
$814.00
Details
Yeast Pongo pygmaeus His tag   1 mg Log in to see 60 to 71 Days
$2,317.33
Details
Yeast Chimpanzee His tag   1 mg Log in to see 60 to 71 Days
$2,317.33
Details
Yeast REACT_Capuchin Monkey His tag   1 mg Log in to see 60 to 71 Days
$2,317.33
Details
Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 11 to 18 Days
$582.75
Details

HBG2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Capuchin Monkey (Cebus)

Chimpanzee

More Proteins for Hemoglobin, gamma G (HBG2) Interaction Partners

Human Hemoglobin, gamma G (HBG2) interaction partners

  1. Data suggest that studying genotype frequency of the Xmn1 gammaG globin polymorphism (-158C>T ) in Siwa Oasis (show CREB3L1 Proteins), Egypt can be considered as a starting point for further research targeting this community sector.

  2. The results suggested that there was a significant relationship between high fetal hemoglobin levels and two variations (-309A/T and -369C/G) in Ggamma gene promotor.

  3. Genetic association studies provide a rationale for functional studies of HBG2 expression in wild-type and T/A/T haplotype erythroblasts and mechanistic studies like chromatin conformation capture experiments, to evaluate the role of chromatin looping as a mediator of the T/A/T haplotype effects on HbF.

  4. In Portuguese beta-thalassemia carriers the HBG2 XmnI polymorphism is strongly associated with HbF levels.

  5. DNA polymorphisms at BCL11A, HBS1L-MYB and Xmn1-HBG2 site loci associated with fetal hemoglobin levels in sickle cell anemia patients from Northern Brazil.

  6. Its polymorphism effects HbF, HbE (show HBe1 Proteins), MCV and MCH (show PMCH Proteins) levels in Thai HbE (show HBe1 Proteins) carriers.

  7. Data indicate that the T to A conversion results in a leucine to histidine amino acid change at codon 105 of the (G)gamma-globin HBG2 gene and caused a hemoglobin (Hb) variant with lowered oxygen affinity.

  8. Hemoglobin gamma G plays a role in modifying clinical symptoms of beta-thalassemia innorthern Thailand.

  9. Data suggest that segregation of BCL11A (show BCL11A Proteins) haplotype 2 indicating an involvement of this locus in Hb F expression.

  10. Hb F is regulated in inherited bone marrow failure syndromes by Xmn1-HBG2, as it is in the haemoglobinopathies.

HBG2 Protein Profile

Protein Summary

The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'- epsilon -- gamma-G -- gamma-A -- delta -- beta--3'.

Gene names and symbols associated with Hemoglobin, gamma G Proteins (HBG2)

  • hemoglobin subunit gamma 2 (HBG2)
  • hemoglobin subunit gamma 2 (hbg2)
  • hemoglobin subunit gamma 2 L homeolog (hbg2.L)
  • hemoglobin, gamma G (HBG2)
  • hemoglobin subunit gamma 2 S homeolog (hbg2.S)
  • hbb2 protein
  • HBG protein
  • MGC88976 protein
  • TNCY protein

Protein level used designations for Hemoglobin, gamma G Proteins (HBG2)

G-gamma globin Paulinia , abnormal hemoglobin , gamma-2-globin , hb F Ggamma , hemoglobin gamma-2 chain , hemoglobin gamma-G chain , hemoglobin subunit gamma-2 , methemoglobin , hemoglobin, gamma G , G-gamma globin , Gamma-globin , Hemoglobin beta-3 , Hemoglobin gamma chain , beta-3 globin , hemoglobin subunit gamma , B2G , beta-2-globin , hemoglobin beta-2 chain , hemoglobin beta-minor chain , hemoglobin subunit beta-2 , larval beta II globin , larval beta-II-globin

GENE ID SPECIES
3048 Homo sapiens
448249 Xenopus (Silurana) tropicalis
100381042 Xenopus laevis
100328858 Oryctolagus cuniculus
397871 Xenopus laevis
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